CClinicalTrials.gg
Not yet recruitingNCT06978530Updated Mar 19, 2026

3D Custom Plate vs. Standard Titanium Plates for Mandibular Sub-condylar Fractures Fixation

An interventional study of 3D custom plate and Standard titanium fixation plates in Mandibular Sub-condylar Fracture, sponsored by Esraa Mosad Tawfik. Not yet recruiting. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-03-19.

Sponsored by Esraa Mosad Tawfik · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
All
01

Study summary

This randomized clinical trial aims to conduct a comprehensive clinical and radiographic evaluation by comparing the efficacy of standard titanium fixation plates with three dimensional custom plate in the management of sub-condylar fractures. By assessing the clinical outcomes, accuracy of reduction of the fracture segments, and bite force promoted by both fixation modalities.

02

Conditions studied

  • Mandibular Sub-condylar Fracture

Browse trials for

Keywords

  • Mandibular fracture
  • 3D custom plate
  • titanium miniplates
  • sub-condylar fractures
03

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Displaced sub condylar fractures, requiring open reduction and rigid internal fixation
  • Age ranges from 18 to 60 years
  • Fracture duration less than 2 weeks
  • Patients with adequate follow up duration for outcome assessment

Exclusion criteria

Exclusion Criteria:

  • Comminuted sub condylar fractures
  • Patients with severe systemic diseases that may affect fracture healing
  • Presence of any pathology at the fracture site
  • Patients with previous history of mandibular surgery
  • Medically compromised patients who are not fit to undergo surgery under general anesthesia
  • Patients with in complete medical records or missing follow up data
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    3D Custom Plate group

    Patients in this group will undergo open reduction and internal fixation of displaced mandibular sub-condylar fractures using preoperatively designed and 3D-printed patient-specific titanium plates. The custom plate is designed based on patient CT data and includes extensions along the posterior border of the mandibular ramus and above the sigmoid notch to facilitate accurate fracture reduction and stable fixation.

    Device: 3D custom plate

  • Active comparator
    Standard titanium plates group

    Patients in this group will undergo open reduction and internal fixation of displaced mandibular sub-condylar fractures using the conventional technique, involving either two standard titanium miniplates or a single 2.3 mm titanium plate.

    Device: Standard titanium fixation plates

Interventions

  • Device3D custom plate

    Custom 3D plate will be designed using preoperative CT and virtual surgical planning.

    Also known as: patient specific plate

  • DeviceStandard titanium fixation plates

    The fixation will be performed according to established surgical principles for managing displaced mandibular sub-condylar fractures without patient-specific planning or customization.

05

What researchers measure

Primary outcomes

  1. Mandibular deviation on opening

    Deviation in mm measured using midline reference.

    Time frame: 1 month, 3 months, and 6 months postoperatively.

  2. Maximum mouth opening

    Distance in mm between incisal edges during maximal mouth opening.

    Time frame: 1 month, 3 months, and 6 months postoperatively.

Secondary outcomes

  1. Bite force

    Bite force measured in Newtons at the molar region using a bite force recording device.

    Time frame: 1 month, 3 months, and 6 months postoperatively

  2. Accuracy of fracture reduction

    Evaluated by comparing preoperative CT with postoperative CT using 3D image superimposition analysis

    Time frame: Immediately postoperative (within 1 week)

06

Study locations

No study locations are listed for this record.

07

Registry details

Key details

Study ID
NCT06978530
Lead sponsor
Esraa Mosad Tawfik
Responsible party
Esraa Mosad Tawfik (Resident, Oral and Maxillofacial Surgery, Cairo University) — Sponsor-investigator
First posted
May 18, 2025
Start date
Apr 10, 2026 (estimated)
Primary completion
Oct 10, 2026 (estimated)
Completion
Nov 1, 2026 (estimated)
Last update
Mar 19, 2026

Study contacts

Esraa Mosaad
Contact
esraa.tawfik@dentistry.cu.edu.eg
+201153918930

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion