Malocclusion, Angle Class II clinical trials

The registry lists 122 studies for Malocclusion, Angle Class II across more than 10 countries. 18 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.

Studies

Recruiting first, then most recently updated. Showing 50 of 122 — search for more.

• Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative TimeRecruitingNCT07841067Not applicable1 country
• Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear PlatesRecruitingNCT05950581Not applicable1 country
• 3D Printed Occlusal Splints for Intraoperative UseNot yet recruitingNCT07079111Not applicable
• Long-term Stability of Treatment With the Twin Block ApplianceEnrolling by invitationNCT077524981 country
• Twin-Block and LIPUS for TMJ Outcomes in Skeletal Class II PatientsRecruitingNCT07676695Not applicable1 country
• LLLLT vs Piezocision in Accelerating Orthodontic Canine RetractionRecruitingNCT07466641Not applicable1 country
• EVALUATION OF TREATMENT CHANGES IN CLASS II DIVISION 1 MALOCCLUSION DURING EN MASSE RETRACTION OF UPPER ANTERIOR TEETH USING MINI IMPLANTS PLACED AT INFRAZYGOMATIC CREST AND INTERRADICULAR SITES A RANDOMIZED CLINICAL TRIAL.RecruitingNCT07405905Not applicable1 country
• Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion.Not yet recruitingNCT07404696Not applicable1 country
• The Effectiveness of the Twin Block and Carriere Motion Appliances in Post-pubertal Patients and an Evaluation of the Impact of Class II Malocclusion and Its Correction on Oral Health-related Quality of LifeNot yet recruitingNCT07292636Not applicable1 country
• Evaluation of a Novel Lip Bumper With Integrated Distal Shoe Appliance in Preventing Second Molar Impaction in Children With Anterior Deep BiteNot yet recruitingNCT07015385Not applicable
• Microbial Adherence, Surface Roughness, Effectiveness and Impact on Patients Between Conventional and 3D Printed Twin Block AppliancesRecruitingNCT06944860Not applicable1 country
• Maxillary Segmental Distalization Using Digitally Printed AppliancesRecruitingNCT06511219Not applicable1 country
• Facial Aesthetic Analysis Model Based on Clinical Cohort Phenotype to Explore 45° Facial Profile.Enrolling by invitationNCT06984666Not applicable1 country
• Evaluation of Diagnostic Accuracy of Artificial Intelligence in Treatment Planning for Non-growing Class II CasesNot yet recruitingNCT06792747
• Invisalign® System with Mandibular AdvancementRecruitingNCT06651944Not applicable1 country
• Assessment of Low Level Laser Therapy Effect on Treatment Outcomes of Bony Supported Distal Jet for Correction of Angle Class II Malocclusion (Randomized Clinical Trial)RecruitingNCT06170099Not applicable1 country
• Maxillary Molar Distalization Supported by Mini-implants With the Advanced Molar Distalization Appliance (Amda®)RecruitingNCT06011382Not applicable1 country
• Effects of Modified Fixed Twin Block Versus Removable Twin Block on Skeletal Class 2 Growing Patients With Mandibular DeficiencyRecruitingNCT05993156Not applicable1 country
• Assesment of Ethnic Bias in an Artificial Intelligence Based Orthodontic Diagnosis SystemCompletedNCT071627531 country
• Root Shortening With Three Methods of Upper Front Teeth RetractionCompletedNCT07744685Not applicable1 country
• AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment PlanningCompletedNCT076907741 country
• A Novel Bi-dimensional Archwire for Miniscrew-supported En-masse RetractionCompletedNCT07664215Not applicable1 country
• Evaluating Laser and Piezocision vs. Piezocision Alone on Root Resorption and Gingival Health During Tooth RetractionCompletedNCT07442825Not applicable1 country
• Study of The Effects of Mandibular Advancement Aligners in Treating Children With Class II Division 1 MalocclusionCompletedNCT07420270Not applicable1 country
• Maxillary Patient Specific Implants in Bimaxillary Orthognathic SurgeryActive, not recruitingNCT06297109Not applicable1 country
• Dento-Alveolar Changes in Maxillary Incisors After En-Masse Retraction Using Two Power-Arm HeightsCompletedNCT07259720Not applicable1 country
• Evaluating the Efficacy of the Sliding Mechanisms on Round-section Arch WireCompletedNCT07243509Not applicable1 country
• Treatment of Class II Malocclusion With Excessive OverjetActive, not recruitingNCT04508322Not applicable1 country
• Removable Devices in Overjet ReductionCompletedNCT06955637Not applicable1 country
• Comparing the Impact of Rubber Bands on Teeth Straightening with Clear Aligners Versus Traditional Braces: a Clinical StudyCompletedNCT06832475Not applicable1 country
• Distalization With Aligners: Anchorage OptionsCompletedNCT06631131Not applicable1 country
• Analysis of the Effect oh the Carriere Motion 3DCompletedNCT067858961 country
• Microanalysis of Changes in 3D Geometry of Orthodontic Mini-implantsActive, not recruitingNCT067433601 country
• Class II Malocclusion Correction Using the Mini-screw Supported Advanced Molar Distalization ApplianceCompletedNCT06726694Not applicable1 country
• Effects of the Herbst Appliance With Different Anchorages and Twin-Block Appliance in Class II MalocclusionActive, not recruitingNCT02411812Not applicable1 country
• Which is Better Piezosurgery or Piezosurgery With Laser in Accelerating Orthodontic Tooth MovementCompletedNCT05655169Not applicable1 country
• Crossbow Versus Forsus Springs in Mild to Moderate Class II Malocclusion CasesCompletedNCT01530516Not applicable1 country
• BRIUS Vs FFA EfficiencyCompletedNCT04347018Not applicable1 country
• Comparative Effect of Clear Aligner Mandibular Advancement and Twin Block Appliances in Class II MalocclusionCompletedNCT066097331 country
• Activator vs the EF Class II Standard in the Treatment of Severe Overjet in Angle Class II Division 1 MalocclusionCompletedNCT06566027Not applicable1 country
• Bone Anchored Carriere Motion ApplianceCompletedNCT05499221Not applicable1 country
• TADs Anchored vs Conventional Anchored Carriere Motion ApplianceCompletedNCT05631353Not applicable1 country
• Tooth Borne Versus Temporary Anchorage Devices (TAD) Based Intrusion Systems for the Correction of Anterior Deep OverbiteCompletedNCT06430710Not applicable1 country
• Mini-implant-supported Twin-Block in Treating Patients With Class II Division 1 MalocclusionCompletedNCT06403033Not applicable1 country
• The Effect of Low-level Laser Therapy on Functional Treatment of Skeletal Class II PatientsCompletedNCT06024382Not applicable1 country
• "Three Dimensional Assessment of Maxillary Molars Following Distalization Using Two Different Approaches"CompletedNCT06240923Not applicable1 country
• Pharyngeal Airway Dimensions With Twinblock Versus Myobrace Appliances in Developing Skeletal Class II PatientsCompletedNCT05610150Not applicable1 country
• Early Versus Late Intermaxillary Elastics in Patients With Class II MalocclusionCompletedNCT06232928Not applicable1 country
• Effects of Skeletal Anchored Versus Incisal Capped Twin Block Appliance in Class II MalocclusionCompletedNCT06209086Not applicable1 country
• Evaluation of Skeletal and Dental Effect of the New Hybrid Aesthetic Functional ApplianceCompletedNCT06209125Not applicable1 country