Malocclusion, Angle Class I clinical trials
The registry lists 35 studies for Malocclusion, Angle Class I across more than 10 countries. 10 are recruiting or about to start. 30 of them are mainly about Malocclusion, Angle Class I (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-15.
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Status
Phase
- Phase 4
- 1
Who runs them
Can Tho University of Medicine and Pharmacy (5) · Damascus University (3) · University of Baghdad (3) · Al-Azhar University (2) · Future University in Egypt (2) · State University of New York at Buffalo (2) · University Hospital, Geneva (1) · Ben Hafeed Dental Center (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth Separation · 3D-Aligners
- Feb 2027LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction · Hesham Nabil Ali Al-Qamhawy
- Apr 2027The Predictability of Directly Printed Versus Thermoformed Clear Aligners · University of Baghdad
- Sep 2027Clinical Performance of Direct-Printed Versus Thermoformed Aligners · University of Baghdad
Who these studies take
Of the 5 Malocclusion, Angle Class I studies recruiting now, 0 (0%) set no upper age limit and 5 (100%) stop at 75 or younger. 4 (80%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (40%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 2 (40%) | 2 (40%) |
| 40 | 0 (0%) | 0 (0%) |
| 50 | 0 (0%) | 0 (0%) |
| 65 | 0 (0%) | 0 (0%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 35 studies, recruiting or not: 74% stop at 75 or younger and 74% at 65; 69% take children; 3% are for women only and 0% for men only; 43% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Malocclusion, Angle Class I studies take
Of 23 interventional studies with no phase under Malocclusion, Angle Class I, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 21 mo15–24 · 23 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 35 of 35. search them.
- Effect of Early Versus Late Premolar Extraction on Orthodontic Tooth MovementRecruitingNCT07773389Not applicable1 country
- 3D Printed Occlusal Splints for Intraoperative UseNot yet recruitingNCT07079111Not applicable
- Clinical Performance of Direct-Printed Versus Thermoformed AlignersRecruitingNCT07637227Not applicable1 country
- Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth SeparationNot yet recruitingNCT07591454Not applicable
- LLLLT vs Piezocision in Accelerating Orthodontic Canine RetractionRecruitingNCT07466641Not applicable1 country
- The Predictability of Directly Printed Versus Thermoformed Clear AlignersEnrolling by invitationNCT07350343Not applicable1 country
- Nano Coated Orthodontic Miniscrews for en Mass Retraction of the Upper ArchRecruitingNCT07521267Not applicable1 country
- Assessment of Treatment Efficacy Using Smile Arc Marginal Ridge Approach Versus MBT Chart Method for Bracket PositioningRecruitingNCT06652230Not applicable1 country
- The Efficacy of Lingual Aligners in Adults.Enrolling by invitationNCT06050655Not applicable1 country
- Effect of Different Grafting Material Following Surgically Facilitated Orthodontics TherapyNot yet recruitingNCT06627829Not applicable1 country
- Assesment of Ethnic Bias in an Artificial Intelligence Based Orthodontic Diagnosis SystemCompletedNCT071627531 country
- The Reliability and Validity of Little's Irregularity Index AssessmentCompletedNCT077458551 country
- Bracket Positioning Techniques and Quality of Orthodontic FinishingCompletedNCT07708363Not applicable1 country
- AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment PlanningCompletedNCT076907741 country
- Direct vs Indirect In-House Clear Aligners vs Fixed Appliances in Orthodontic TreatmentCompletedNCT07687329Not applicable1 country
- Micro-Osteoperforations to Accelerate Maxillary Canine Retraction in Class I MalocclusionCompletedNCT07155018Not applicable1 country
- A Comparison Between GUMMETAL and SS Orthodontic Wires in Space ClosureCompletedNCT04591080Not applicable1 country
- Friction or Frictionless: What is the Most Effective Method for Retracting Anterior Teeth?CompletedNCT06928896Not applicable1 country
- Antibiofilm Activity of Chitosan Nanoparticles Incorporated Into Clear AlignersActive, not recruitingNCT06823310Not applicable1 country
- Microanalysis of Changes in 3D Geometry of Orthodontic Mini-implantsActive, not recruitingNCT067433601 country
- Effectives of Non-extraction Orthodontic Treatment of Angle Class I MalocclusionCompletedNCT06638983Not applicable1 country
- Root Resorption and Alveolar Bone in the Maxillary Canine Retraction Using Injectable Platelet-rich Fibrin: A Split-Mouth TrialCompletedNCT06634888Not applicable1 country
- BRIUS Vs FFA EfficiencyCompletedNCT04347018Not applicable1 country
- Evaluating the Effect of Injectable Platelet Rich Fibrin on Tooth MovementCompletedNCT06562452Not applicable1 country
- Effectiveness of Clear Aligners in Different ThicknessesCompletedNCT06504498Not applicable1 country
- Predictability of Part-time Wearing of Removable Clear Aligner Therapy Versus Full TimeCompletedNCT06253286Not applicable1 country
- Compartive Evalution of the Efficiency of Maxillary Canine Retraction Using Power Chain Versus Burstone T-loopActive, not recruitingNCT05882526Not applicable1 country
- Comparison Between Clear Aligners and Traditional Fixed Appliances in the Treatment of Four-premolar-extraction CasesCompletedNCT03645356Not applicable1 country
- Effect of Systemic Administration of Vitamin D on the Rate of Orthodontic Tooth Movement - A Randomized Control TrialCompletedNCT05202496Not applicable1 country
- Acceleration of Alignment of Crowded Lower Anterior TeethCompletedNCT03659097Not applicable1 country
- The Role of Low Level Laser Therapy in Acceleration of Teeth Alignment in Lingual Orthodontic PatientsCompletedNCT03646942Not applicable1 country
- 3D Comparison of Anterior Teeth Retraction and Anchorage Control Between En-masse and Two-step MechanicsStatus unknownNCT03903575Not applicable1 country
- A Biotype Enhancing Strategy For The Patient Undergoing Accelerated OrthodonticsStatus unknownNCT02866929Phase 4
- Arch Dimension and Inclination of the Upper and Lower Incisors ChangesStatus unknownNCT03129919Not applicable
- Efficiency of Piezo-Corticision in Accelerating Orthodontic Tooth MovementStatus unknownNCT02549950Not applicable1 country