Lung Diseases, Obstructive clinical trials
The registry lists 202 studies for Lung Diseases, Obstructive across more than 10 countries. 22 are recruiting or about to start. 50 of them are mainly about Lung Diseases, Obstructive (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 11 narrower conditions too, such as Pulmonary Disease, Chronic Obstructive: 11,199 studies, 1,578 open.
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Status
Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (25) · AstraZeneca (20) · University of Zurich (7) · University of Michigan (5) · Royal Brompton & Harefield NHS Foundation Trust (4) · Novartis Pharmaceuticals (4) · Radboud University Medical Center (3) · Columbia University (3)
What is being tested here
Drugs under test in Lung Diseases, Obstructive studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| GSK3862995B | 1 | 0 | 1 |
| Felcorekibart | 1 | 0 | 1 |
| AERO-002 | 1 | 0 | 1 |
| Vimseltinib | 1 | 0 | 1 |
| Benralizumab | 0 | 12 | 12 |
| Glycopyrrolate | 0 | 2 | 4 |
| Acetazolamide | 0 | 0 | 3 |
| Azithromycin | 0 | 0 | 2 |
| Tralokinumab | 0 | 2 | 2 |
| PF-610355 | 0 | 0 | 2 |
Drug classes tested here Corticosteroids 5 · Antimuscarinics 5 · Bronchodilators 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8, phase 3 first
- Sep 2027A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD) · Phase 3 · Grifols Therapeutics LLC
- Dec 2026Secondhand Smoke Respiratory Health Study · University of California, San Francisco
- Apr 2027Effect of Dietary Fiber Supplementation on Systemic Inflammation and Clinical Parameters in COPD · Júnea Regina Pires Drews
- Jun 2027Phase 2b Efficacy and Safety Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD Patients · AeroRx Therapeutics Inc.
- Jun 2027Cough Capture as a Portal Into the Lung · Albert Einstein College of Medicine
- Jun 2027TCM Daoyin Therapy in Individuals At-risk for COPD · Shanghai University of Traditional Chinese Medicine
- Aug 2027Measurement of Viscoelastic Properties of Bronchopulmonary Secretions. · Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Nov 2027Impact of Multidisciplinary Care, Structured and Targeted on the COPD Patient's Clinical Pathway. · Centre Hospitalier Universitaire de Nīmes
Who these studies take
Of the 15 Lung Diseases, Obstructive studies recruiting now, 10 (67%) set no upper age limit and 2 (13%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (27%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 10 (67%) | 10 (67%) |
| 30 | 12 (80%) | 12 (80%) |
| 40 | 15 (100%) | 15 (100%) |
| 50 | 15 (100%) | 15 (100%) |
| 65 | 14 (93%) | 14 (93%) |
| 75 | 14 (93%) | 14 (93%) |
| 85 | 12 (80%) | 12 (80%) |
Across all 202 studies, recruiting or not: 29% stop at 75 or younger and 10% at 65; 26% take children; 1% are for women only and 8% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lung Diseases, Obstructive studies take
Of 15 phase 3 interventional studies under Lung Diseases, Obstructive, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 27 mo20–45 · 15 studies | — | — |
| Interventional, no phase | 25 mo11–39 · 28 studies | — | — |
| Observational | 27 mo11–53 · 25 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
Newly registered3
- A Study to Assess the Efficacy and Safety of Co-administration of GSK3862995B With GSK5784283 in Adult Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)Nov 4, 2026NCT07915791
- Impact of Multidisciplinary Care, Structured and Targeted on the COPD Patient's Clinical Pathway.Oct 30, 2026NCT07907601
- Phase 2b Efficacy and Safety Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD PatientsOct 26, 2026NCT07896252
Studies
Recruiting first, then most recently updated. Showing 50 of 202. Browse all 202 → or search them.
- THERMotherapy Against Persistent Bacterial LUNG InfectionsRecruitingNCT05351242Not applicable1 country
- A Study to Assess the Efficacy and Safety of Co-administration of GSK3862995B With GSK5784283 in Adult Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)Not yet recruitingNCT07915791Phase 2
- Impact of Multidisciplinary Care, Structured and Targeted on the COPD Patient's Clinical Pathway.Not yet recruitingNCT07907601Not applicable1 country
- Phase 2b Efficacy and Safety Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD PatientsRecruitingNCT07896252Phase 21 country
- A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)RecruitingNCT07555483Phase 39 countries
- BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled AsthmaRecruitingNCT05341726Not applicable1 country
- Using Community Health Workers to Support Rural Care Partners of Seriously Ill Older VeteransNot yet recruitingNCT06963970Not applicable1 country
- Effect of Dietary Fiber Supplementation on Systemic Inflammation and Clinical Parameters in COPDNot yet recruitingNCT07868211Not applicable1 country
- FCV vs VCV in Obstructive and Asthmatic PatientsRecruitingNCT06563544Not applicable1 country
- Lung Health and the Microbiome Among Adults in Botswana: the Go-hema CohortRecruitingNCT076996141 country
- Measurement of Viscoelastic Properties of Bronchopulmonary Secretions.RecruitingNCT03888300Not applicable1 country
- World Trade Center Particulate Matter Induced Cardiorespiratory and Vascular Dysfunction: a MultiOmic Approach (CaRVD)RecruitingNCT052151711 country
- Cough Capture as a Portal Into the LungRecruitingNCT058545631 country
- Longitudinal Pulmonary Chronic Graft-versus-host-disease (GvHD) Assessment in Hematopoietic Stem Cell Transplantation (HSCT) PatientsRecruitingNCT072973031 country
- A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)RecruitingNCT06619561Phase 21 country
- The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of EmphysemaRecruitingNCT06655428Not applicable3 countries
- Efficacy of EFA in Acquired Brain InjuryRecruitingNCT05993364Not applicable1 country
- Determination of Posture in Patients With Restrictive and Obstructive Lung DiseaseNot yet recruitingNCT063064821 country
- Prospective, Observational Study of Wellinks Effect on COPD Hospital ReadmissionsRecruitingNCT053305071 country
- The Significance of Circulating Microvesicles in Pulmonary Hypertension Due to Chronic Obstructive Pulmonary DiseaseNot yet recruitingNCT052501281 country
- Antibiotic Stewardship in AECOPD Through CRP-Guided ManagementNot yet recruitingNCT05286918Not applicable1 country
- Early COPD for China Pulmonary Health Study Stage IIRecruitingNCT050289851 country
- A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin DeficiencyCompletedNCT04722887Phase 1/21 country
- Prevalence and Determinants of Therapeutic Non-Compliance in Patients With Chronic Pathologies ( PDTNCCP)CompletedNCT078645321 country
- A Study Evaluating the Effect of Inhaled PT007(AS MDI) Versus Placebo MDI and Ventolin Evohaler on Lung Function in Adult Participants With AsthmaCompletedNCT06644924Phase 21 country
- Clinical and Autonomic Efficacy of Digital-Gamified Diaphragmatic Training in Pediatric Pulmonary RehabilitationActive, not recruitingNCT07765264Not applicable1 country
- Management of Complex Airway Stenoses With Dedicated Tailored Stents Wrought by 3D Computer-assisted ConceptionCompletedNCT02889029Not applicable1 country
- Secondhand Smoke Respiratory Health StudyActive, not recruitingNCT02797275Phase 41 country
- TCM Daoyin Therapy in Individuals At-risk for COPDActive, not recruitingNCT05940480Not applicable1 country
- Can NAVA Mode Reduce Mechanical Ventilation Day in Patients With COPD ?CompletedNCT05595733Not applicable1 country
- French Validation of the CAPTURE Case Finding Tool for Obstructive Respiratory DiseaseTerminatedNCT056545971 country
- Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy With Chronic Lung DiseasesCompletedNCT06385301Not applicable1 country
- Improving Patient Prioritization During Hospital-homecare TransitionCompletedNCT04136951Not applicable1 country
- RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory InfectionCompletedNCT06149494Phase 21 country
- Unrefined Salmon Oil as Dietary Supplement in Patient With Chronic Obstructive Pulmonary DiseaseWithdrawnNCT05130294Not applicable1 country
- A Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Safety and Efficacy of Briquilimab in Participants With Allergic AsthmaTerminatedNCT06592768Phase 11 country
- Airway Effects of Tiotropium in Patients With COPDCompletedNCT02683668Phase 31 country
- Ryme Medical TLD Pilot StudyActive, not recruitingNCT05967091Not applicable6 countries
- REported Outcomes in COPD With Trixeo in Real worlD in GermanyCompletedNCT053113061 country
- Individualizing Treatment for Asthma in Primary CareCompletedNCT06272370Phase 41 country
- In Patients With Obstructive Airway Disease, Investigate the Effects of Different Breathing Strategies and Pedaling Rates on the Physiological Response to Bicycle ExerciseActive, not recruitingNCT063328201 country
- AECOPD and Nutritional Supplementation in COPDCompletedNCT06801964Not applicable1 country
- Indoor Air Quality for Black Adults With Uncontrolled AsthmaCompletedNCT056853811 country
- Holistic Wellbeing in COPD: Communication About Sexuality (COSY)CompletedNCT05696730Not applicable1 country
- A Population-based Investigation of Asthma in the Telemark Region of NorwayActive, not recruitingNCT020737081 country
- Effects of Supervision During a Community-based Exercise Intervention (Urban Training) in Patients With COPDCompletedNCT05565872Not applicable1 country
- Cardio-pulmonary Rehabilitation and Sleep QualityCompletedNCT046685991 country
- Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided CryoprobeCompletedNCT05399082Not applicable1 country
- Observational Study of Obstructive Lung Disease (NOVELTY)CompletedNCT0276032919 countries
- High Flow Nasal Cannula Therapy in Bronchiolitis : Early vs RescueCompletedNCT03095495Not applicable1 country