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RecruitingNCT03888300VLM-2Updated Apr 29, 2026

Measurement of Viscoelastic Properties of Bronchopulmonary Secretions.

An interventional study of Physiotherapy in Obstructive Pulmonary Disease, sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain. Recruiting at 1 site in Belgium. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-29.

Sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Started Aug 2019; still recruiting 7 years 3 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
500
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

The study is experimental and aims to (a) compare the viscoelastic properties of bronchial secretions obtained in patients suffering from obstructive respiratory disease, and (b) to compare the viscoelastic properties of bronchial secretions obtained in patients before and after application of a respiratory physiotherapy or exercise as usually prescribed.

After agreement, the sputum of the participants will be collected according to the method used in clinical routine.Experiments (collection and analysis of sputum) will be conducted at the Saint-Luc University Clinic.

02

Conditions studied

  • Obstructive Pulmonary Disease
03

In context

Lung Diseases, Obstructive

202 studies on the registry are indexed under Lung Diseases, Obstructive; 22 are open to participants now.

This study's planned enrollment of 500 is above the median of 112 across 123 interventional studies indexed under Lung Diseases, Obstructive.

Browse Lung Diseases, Obstructive studies →

Lead sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain is the lead sponsor of 350 studies on the registry; 64 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • obstructive pulmonary disease

Exclusion criteria

Exclusion Criteria:

  • none
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
500 participants (estimated)

Study arms

  • Experimental
    Patient Group

    Patients with obstructive pulmonary diseases receiving standard physiotherapy treatment

    Other: Physiotherapy

Interventions

  • OtherPhysiotherapy

    Chest Physiotherapy, physical exercises

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What researchers measure

Primary outcomes

  1. Viscoelasticity

    Evolution of elastic modulus, viscous modulus, phase angle and non-linear characteristics of lung secretions.

    Time frame: 30 minutes

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Aug 2019 (actual). Primary completion is estimated for Aug 2027, 96 months after the start.

Of 28 interventional studies with no phase under Lung Diseases, Obstructive, half reached primary completion within 25 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 39. This study's planned 96 months is above that.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 20, 2019
First posted
Mar 25, 2019
StartActual
Aug 1, 2019
Primary completionEst.
Aug 1, 2027
CompletionEst.
Aug 1, 2027
Last update
Apr 29, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 29, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03888300
Responsible party
Sponsor
First posted
Mar 25, 2019
Start date
Aug 1, 2019
Primary completion
Aug 1, 2027 (estimated)
Completion
Aug 1, 2027 (estimated)
Last update
Apr 29, 2026

Study contacts

Gregory Reychler, PT, PhD
Contact
gregory.reychler@uclouvain.be
+3227642316
William PONCIN, PT, PhD
Contact
william.poncin@uclouvain.be
Gregory Reychler, PT, PhD
principal investigator · Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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