Intraocular Lymphoma clinical trials
The registry lists 165 studies for Intraocular Lymphoma across more than 10 countries. 9 are recruiting or about to start. 17 of them are mainly about Intraocular Lymphoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-28.
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Who runs them
National Cancer Institute (NCI) (32) · Fred Hutchinson Cancer Center (14) · City of Hope Medical Center (6) · Memorial Sloan Kettering Cancer Center (6) · Barbara Ann Karmanos Cancer Institute (5) · Case Comprehensive Cancer Center (5) · Northwestern University (4) · Wake Forest University Health Sciences (4)
What is being tested here
Drugs under test in Intraocular Lymphoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Rituximab | 2 | 0 | 12 |
| Methotrexate | 2 | 0 | 7 |
| Lenalidomide | 1 | 0 | 6 |
| Atropine | 1 | 0 | 1 |
| Zanubrutinib | 1 | 0 | 1 |
| Ascorbic Acid | 1 | 0 | 1 |
| Cyclophosphamide | 0 | 1 | 10 |
| Fludarabine phosphate | 0 | 1 | 8 |
| Fludarabine | 0 | 1 | 8 |
| Etoposide | 0 | 1 | 6 |
Drug classes tested here Antimetabolites 2 open · Tyrosine kinase inhibitors (TKIs) 1 open · Alkylating agents 16 · Calcineurin inhibitors 9 · HDAC inhibitors 8
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Aug 2027Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery · Cairo University
- Oct 2027ZR-MTX for PIOL Phase II Trial · Peking Union Medical College Hospital
- Nov 2027Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery · Rayner Intraocular Lenses Limited
Who these studies take
Of the 6 Intraocular Lymphoma studies recruiting now, 3 (50%) set no upper age limit and 2 (33%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (67%) | 4 (67%) |
| 30 | 4 (67%) | 4 (67%) |
| 40 | 4 (67%) | 4 (67%) |
| 50 | 4 (67%) | 4 (67%) |
| 65 | 6 (100%) | 6 (100%) |
| 75 | 6 (100%) | 6 (100%) |
| 85 | 4 (67%) | 4 (67%) |
Across all 165 studies, recruiting or not: 25% stop at 75 or younger and 13% at 65; 28% take children; 0% are for women only and 0% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Intraocular Lymphoma studies take
Of 10 phase 1 interventional studies under Intraocular Lymphoma, half reached primary completion within 39 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 39 mo37–71 · 10 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 165. Browse all 165 → or search them.
- Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic CancerRecruitingNCT011376431 country
- Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract SurgeryNot yet recruitingNCT07099079
- ZR-MTX for PIOL Phase II TrialRecruitingNCT06973811Phase 21 country
- Registry of Older Patients With CancerRecruitingNCT011378251 country
- Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation SurgeryNot yet recruitingNCT07364370Not applicable1 country
- Multicentre Implementation and Validation of a Molecular Diagnostic for VitreoRetinal LymphomaRecruitingNCT058419141 country
- Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard CataractsRecruitingNCT06781970Not applicable1 country
- Clinical Outcomes of Patients with LAL+ in At Least One EyeEnrolling by invitationNCT066503581 country
- Intravitreal Methotrexate and R2(Rituximab & Lenalidomide) Regimen in Newly-diagnosed Primary Vitreoretinal LymphomaRecruitingNCT03746223Phase 21 country
- Fusion Protein Cytokine Therapy After Rituximab in Treating Patients With B-Cell Non-Hodgkin LymphomaCompletedNCT00720135Phase 11 country
- Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell TransplantActive, not recruitingNCT011995621 country
- 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With CancerActive, not recruitingNCT009350901 country
- Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin LymphomaActive, not recruitingNCT01815749Phase 11 country
- Lenalidomide and Combination Chemotherapy (DA-EPOCH-R) in Treating Patients With MYC-Associated B-Cell LymphomasCompletedNCT02213913Phase 1/21 country
- Evaluation of the Visual Acuity Curves of an Enhanced Monofocal Intraocular LensCompletedNCT074398351 country
- Demographics and Clinical Characteristics of Ocular Inflammatory Diseases in SingaporeActive, not recruitingNCT071761301 country
- Evaluation of Axial Stability of Two Models of Intraocular Lenses in Patients With an Eye Length More Than 26 mmCompletedNCT05129566Not applicable1 country
- Ipilimumab and Local Radiation for Selected Solid TumorsTerminatedNCT01769222Phase 11 country
- Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid MalignanciesCompletedNCT01523223Phase 11 country
- Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment RegimenTerminatedNCT00074165Phase 21 country
- Physician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage CancerCompletedNCT00002520Not applicable1 country
- Study of Ibrutinib in Patients With Relapsed or Refractory Primary Central Nervous Lymphoma or Intraocular LymphomaCompletedNCT02542514Phase 21 country
- Mutation Detection for VRLStatus unknownNCT051029941 country
- Collecting and Storing Blood Samples From Patients With CancerWithdrawnNCT00900120
- Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal MetastasesCompletedNCT00424242Early Phase 11 country
- Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ LymphomasTerminatedNCT01805037Phase 1/21 country
- Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic CancerCompletedNCT00003816Phase 2/31 country
- Bortezomib and Filgrastim to Promote Stem Cell Mobilization in Patients With Non-Hodgkin Lymphoma or Multiple MyelomaCompletedNCT02037256Not applicable1 country
- High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid TumorsCompletedNCT00536601Not applicable1 country
- Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid MalignanciesTerminatedNCT01678443Phase 11 country
- Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic MalignanciesTerminatedNCT01643603Phase 11 country
- Study of Akt Inhibitor MK2206 in Patients With Relapsed LymphomaCompletedNCT01258998Phase 21 country
- Methadone, Morphine, or Oxycodone in Treating Pain in Patients With CancerTerminatedNCT00726830Not applicable1 country
- Lenalidomide Plus Rituximab for Recurrent/Refractory CNS and Intraocular LymphomaCompletedNCT01542918Phase 11 country
- Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical TrialCompletedNCT00750009Phase 31 country
- Dasatinib for Modulating Immune System After Autologous Stem Cell Transplants for Multiple Myeloma, Non-Hodgkin, or Hodgkin LymphomaTerminatedNCT01609816Phase 11 country
- The Clinical Importance of Angle Alpha by Multifocal Intraocular Lenses.CompletedNCT04274088
- Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic CancerCompletedNCT00089011Phase 22 countries
- Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic CancerCompletedNCT00006251Phase 1/22 countries
- Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic MalignanciesCompletedNCT00014235Not applicable3 countries
- Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple MyelomaCompletedNCT00003196Not applicable3 countries
- Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid TumorsCompletedNCT01326702Phase 1/21 country
- Monoclonal Antibody Therapy in Treating Patients With Refractory Advanced Solid Tumors or LymphomaCompletedNCT00049712Phase 11 country
- Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic MalignanciesCompletedNCT01839916Phase 21 country
- Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular LymphomaCompletedNCT01722305Phase 11 country
- Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell TransplantationTerminatedNCT01116232Phase 21 country
- Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial CancerTerminatedNCT00499733Early Phase 11 country
- Azacitidine Plus Phenylbutyrate in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous TreatmentCompletedNCT00005639Phase 11 country
- Vaccine Therapy and GM-CSF in Treating Patients With CNS LymphomaWithdrawnNCT00621036Phase 21 country
- Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic CancerCompletedNCT00005092Phase 11 country