An observational study in Uveitis, Scleritis and Episcleritis and Endophthalmitis, sponsored by Singapore National Eye Centre. Active, not recruiting at 1 site in Singapore. Open to participants aged 21 Years to 99 Years. Per ClinicalTrials.gov, last updated 2025-09-16.
Sponsored by Singapore National Eye Centre · Observational
This is a retrospective study analyzing demographics, clinical characteristics, treatment received, and outcomes of ocular inflammatory diseases that presented to the Singapore National Eye Centre (SNEC).
This is a retrospective, cross-sectional study. In this study, the investigators aim to investigate demographics, clinical characteristics, treatment received, and outcomes of ocular inflammatory diseases, including masquerade syndromes such as ocular neoplasms (e.g., vitreoretinal and uveal lymphoma) and endophthalmitis that presented to the Singapore National Eye Centre (SNEC). Data on demographics, clinical features, diagnosis, investigations, secondary complications, treatment received, and outcomes will be analyzed using statistical software. The results of this study will lead to an improved clinical practice with better treatment selections and an optimized monitoring protocol for follow-up care for patients with ocular inflammatory diseases, including masquerade syndromes such as ocular neoplasms (e.g.,vitreoretinal and uveal lymphoma) and endophthalmitis. This will lead to better clinical outcomes and prevention of serious sight-threatening complications.
Patients diagnosed with ocular inflammatory diseases, including masquerade syndromes such as ocular neoplasms (e.g., vitreoretinal and uveal lymphoma) and endophthalmitis, at the Singapore National Eye Centre.
Exclusion Criteria:
Patients diagnosed with uveitis at Singapore National Eye Centre
Other: No Intervention: Observational Cohort
Patients diagnosed with scleritis or episcleritis at Singapore National Eye Centre
Other: No Intervention: Observational Cohort
Patients diagnosed with ocular neoplasms at Singapore National Eye Centre
Other: No Intervention: Observational Cohort
Patients diagnosed with endophthalmitis at Singapore National Eye Centre
Other: No Intervention: Observational Cohort
Not applicable, No intervention. Observational study.
Distribution of demographics, diagnosis, clinical features, treatment and outcomes
Percentage ethnic distribution, percentage of gender distribution, percentage of age distribution, percentage of etiology, percentage of clinical features, percentage of investigations, percentage of diagnosis, percentage of secondary complications, percentage of treatment received, percentage of outcomes
Time frame: January 1987 and January 2025
Correlation of demographics, diagnosis, clinical features, and treatment outcomes
To evaluate the independent and combined effects of demographic factors, diagnostic categories, and clinical features on treatment outcomes using multivariate logistic and cox regression analysis
Time frame: January 1987 and January 2025
Plan to share: No — IPD will not be shared. Anonymous data.
This study is active, not recruiting, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Singapore National Eye Centre