Hypopituitarism clinical trials
The registry lists 47 studies for Hypopituitarism across more than 10 countries. 8 are recruiting or about to start. 25 of them are mainly about Hypopituitarism (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-26. Counting its narrower condition Dwarfism, Pituitary too: 290 studies, 36 open.
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Who runs them
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (4) · University of Aarhus (4) · Rigshospitalet, Denmark (2) · Massachusetts General Hospital (2) · Eli Lilly and Company (2) · A.O.U. Città della Salute e della Scienza (2) · Versartis Inc. (1) · Federico II University (1)
What is being tested here
Drugs under test in Hypopituitarism studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Apr 2027Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease · Massachusetts General Hospital
- May 2027Sleep Disorders in Hypothalamic and Pituitary Damage · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
- Jun 2027Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin Deficiency · Elizabeth Austen Lawson
Who these studies take
Of the 6 Hypopituitarism studies recruiting now, 1 (17%) set no upper age limit and 3 (50%) stop at 75 or younger. 1 (17%) take children under 18. 0 (0%) are for women only and 1 (17%) for men only; 2 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (17%) | 1 (17%) |
| 18 | 5 (83%) | 6 (100%) |
| 30 | 4 (67%) | 5 (83%) |
| 40 | 4 (67%) | 5 (83%) |
| 50 | 4 (67%) | 5 (83%) |
| 65 | 4 (67%) | 5 (83%) |
| 75 | 2 (33%) | 3 (50%) |
| 85 | 1 (17%) | 1 (17%) |
Across all 47 studies, recruiting or not: 55% stop at 75 or younger and 45% at 65; 23% take children; 4% are for women only and 15% for men only; 32% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 47 of 47. search them.
- Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin DeficiencyRecruitingNCT04789148Phase 11 country
- Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary DiseaseRecruitingNCT07568509Early Phase 11 country
- Charactertizing Growth Hormone Deficiency in Traumatic Brain InjuryRecruitingNCT077957361 country
- Sleep Disorders in Hypothalamic and Pituitary DamageRecruitingNCT071432661 country
- Pituitary Function After Recovery From Septic Shock Among ICU SurvivorsRecruitingNCT059904911 country
- Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical ModelsNot yet recruitingNCT06326853
- Improving Survivorship and Health-related Quality of Life in Patients With Primary Brain TumoursNot yet recruitingNCT06014398Not applicable1 country
- Growth Hormone Replacement Therapy for Retried Professional Football PlayersRecruitingNCT04121780Phase 21 country
- Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)CompletedNCT04897802Phase 41 country
- Long-Term Outcomes of Hypopituitarism Following Gamma Knife Radiosurgery for Pituitary AdenomasCompletedNCT070156451 country
- Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study)CompletedNCT05319301Not applicable1 country
- Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study)CompletedNCT04902235Phase 41 country
- Quality of Life and Psychosocial Dimension in Children With HypopituitarismStatus unknownNCT054032551 country
- Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy ControlsCompletedNCT04648137Not applicable1 country
- Stimulation Test With Intranasal Glucagon for Corticotroph, Somatotroph and Antidiuretic AxesCompletedNCT05206149Phase 41 country
- Acute Neuroendocrine Response to Intravenous Infusion of Diclofenac SodiumCompletedNCT05188131Phase 41 country
- Pituitary Functions After Traumatic Brain Injury (TBI) and/or Subarachnoid Hemorrhage (SAH)CompletedNCT005071041 country
- Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen TestCompletedNCT00851942Phase 41 country
- Lipolytic Effects of GH in Hypopituitary Patients in VivoCompletedNCT02782208Not applicable1 country
- Ante-hypophyseal Dysfunctions in Children Following Moderate to Severe Traumatic Brain InjuriesCompletedNCT01250132Not applicable1 country
- Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoietic Stem Cell Transplant RecipientsTerminatedNCT005042181 country
- Next Day Growth Hormone Predicting Pituitary Function After AdenomectomyStatus unknownNCT037085231 country
- The Influence of Different Hydrocortisone Replacement Doses on the Partitioning and Flexibility of Ectopic Lipids in Patients With Corticotropic HypopituitarismTerminatedNCT02360046Not applicable1 country
- Effects of Growth Hormone on Cognition and Cerebral Metabolism in Adults With Growth Hormone DeficiencyCompletedNCT01007071Phase 31 country
- The Effect of Pharmacological Antilipolysis on the Metabolic Effects of GhrelinCompletedNCT01209416Not applicable1 country
- Optimising Steroid Replacement in Patients With Adrenal InsufficiencyStatus unknownNCT03282487Phase 41 country
- An Observational Study (Registry) Assessing Treatment Outcomes and Safety for Children and Adults Who Are Prescribed Norditropin® (Human Growth Hormone)CompletedNCT010099051 country
- Pubertal Induction in Individuals With HypogonadismStatus unknownNCT028719861 country
- Efficacy of Pulsatile GnRH Therapy on Male Patients With Pituitary Stalk Interruption SyndromeStatus unknownNCT02705014Not applicable1 country
- Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve HypoplasiaCompletedNCT00140413Phase 41 country
- Androgen Replacement Therapy in Women With HypopituitarismCompletedNCT00027430Not applicable1 country
- Posttraumatic Hypopituitarism - Incidence, Predictors and Test ValidityCompletedNCT01028742
- Testosterone and Growth Hormone for Bone Loss in MenCompletedNCT00080483Phase 21 country
- A Prospective Observational Study of Effect of Somatropin on Growth Hormone Deficient AdultsCompletedNCT01088399
- Central Hypothyroidism and Cardiovascular RiskCompletedNCT015748591 country
- Hormone Deficiency After Brain Injury During CombatStatus unknownNCT016669641 country
- VRS-317 in Adult Subjects With Growth Hormone DeficiencyCompletedNCT01359488Phase 11 country
- Arimidex Multicenter Trial in Growth Hormone (GH) Deficient BoysCompletedNCT00133354Phase 2/31 country
- Effects of Corticotropin Releasing Hormone (CRH) on the Sleep in Patients With HypopituitarismCompletedNCT00666068Not applicable1 country
- Central Hypothyroidism, a Novel Laboratory MeasurementStatus unknownNCT01280292Not applicable
- Hypopituitarism After Aneurismal Subarachnoid HemorrhageCompletedNCT009625591 country
- Ghrelin, Growth Hormone and Cortisol Interaction in Growth Hormone Deficient PatientsCompletedNCT00139945Not applicable1 country
- Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine SupplementationCompletedNCT00360074Phase 41 country
- Oestrogen Withdrawal in Hypopituitary WomenCompletedNCT00572390Not applicable1 country
- Effect of 5 Years of GH Replacement on AtherosclerosisCompletedNCT004624751 country
- Comparison of Two Growth Hormone Dosing Methods in Adults With Growth Hormone DeficiencyCompletedNCT00490191Phase 46 countries
- Cardiovascular Risk Factors and LCH in AdultsStatus unknownNCT004839251 country