An observational study in Hypopituitarism, sponsored by Rigshospitalet, Denmark. Completed at 1 site in Denmark. Per ClinicalTrials.gov, last updated 2013-04-02.
Sponsored by Rigshospitalet, Denmark · Observational
Retrospective trial of 300 patients with pituitary insufficiency treated in Department of Medica Endocrinology, Rigshospitalet, Copenhagen University concerning levothyroxine (T4) replacement and cardiovascular risk factors. The hypothesis is that subtle central hypothyroidism is associated with adverse cardiac risk factors, such as body composition and serum lipids, and that improved T4 replacement will eliminate this increased risk, independently of other pituitary hormone replacements.
Retrospective trial of 300 patients with pituitary insufficiency treated in Department of Medical Endocrinology, Rigshospitalet, Copenhagen University concerning levothyroxine (T4) replacement and cardiovascular risk profile. The patient files are recruited among hypopituitary patients treated with growth hormone from the period 1993 to 2008. The trial is a retrospective assessment of data already collected for routine purposes and thus an audit of daily clinical practice. All information on the patients is obtained from the paper and electronic files existing in the department and no new measurements are foreseen.
47 studies on the registry are indexed under Hypopituitarism; 8 are open to participants now.
This study's enrollment of 200 is above the median of 137 across 17 observational studies indexed under Hypopituitarism.
Browse Hypopituitarism studies →Rigshospitalet, Denmark is the lead sponsor of 1,007 studies on the registry; 175 are open to participants now.
Counted across the registry records on this site, refreshed daily.
all patients at Rigshospitalet treated for pituitary hypothyroidism in the years 1993 to 2008
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Exclusion Criteria:
group of patients with hypopituitarism
Other: levothyroxine
titration of T4 according to biochemical values
cholesterol
Time frame: March 2002 - March 2013
This study is completed, as verified in Mar 2013. You cannot join it, but the record below documents what was studied.
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