Hypophosphatemia clinical trials
The registry lists 53 studies for Hypophosphatemia across more than 10 countries. 16 are recruiting or about to start. 25 of them are mainly about Hypophosphatemia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 2 narrower conditions too, such as Familial Hypophosphatemic Rickets: 98 studies, 19 open.
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Who runs them
National Institute of Dental and Craniofacial Research (NIDCR) (3) · University Hospital, Brest (2) · Yale University (2) · Hospices Civils de Lyon (2) · Ain Shams University (2) · Pharmacosmos A/S (2) · Indiana University (1) · University Hospital, Geneva (1)
What is being tested here
Drugs under test in Hypophosphatemia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Effects of Treatments for Anemia and Iron Deficiency on the Electrolyte Balance in Lung Transplant Recipients: A Special Focus on Hypophosphatemia · University of Zurich
- Feb 2027Protocolised Management of Phosphate Replacement Trial · Caboolture Hospital
- May 2027Evaluation of Dipyridamole in Preventing Post-Transplant Hypophosphatemia in Kidney Transplant Recipients · Stanford University
Who these studies take
Of the 11 Hypophosphatemia studies recruiting now, 7 (64%) set no upper age limit and 2 (18%) stop at 75 or younger. 3 (27%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (18%) | 2 (18%) |
| 18 | 11 (100%) | 11 (100%) |
| 30 | 10 (91%) | 10 (91%) |
| 40 | 10 (91%) | 10 (91%) |
| 50 | 10 (91%) | 10 (91%) |
| 65 | 10 (91%) | 10 (91%) |
| 75 | 9 (82%) | 9 (82%) |
| 85 | 8 (73%) | 8 (73%) |
Across all 53 studies, recruiting or not: 17% stop at 75 or younger and 13% at 65; 28% take children; 4% are for women only and 2% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypophosphatemia studies take
Of 14 observational studies under Hypophosphatemia, half reached primary completion within 17 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Observational | 17 mo6–24 · 14 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- Phosphate & Kidney StonesOct 29, 2026NCT07903961
Studies
Recruiting first, then most recently updated. Showing 50 of 53. Browse all 53 → or search them.
- A First-in-human Study of KK8123 in Adults With X-linked HypophosphatemiaRecruitingNCT06525636Phase 1/25 countries
- Phosphate & Kidney StonesNot yet recruitingNCT07903961Early Phase 11 country
- Respiratory Quotient and Phosphate Changes During Early Critical IllnessNot yet recruitingNCT07800143
- Phosphate in Acute PancreatitisRecruitingNCT07681050Phase 21 country
- Phosphorus-31 Spectroscopy in Phosphate DiabetesRecruitingNCT06921720Not applicable1 country
- Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical DiagnosisNot yet recruitingNCT07666269Not applicable1 country
- Evaluation of Dipyridamole in Preventing Post-Transplant Hypophosphatemia in Kidney Transplant RecipientsRecruitingNCT06824454Phase 21 country
- The Impact of Phosphate Metabolism on Healthy AgingRecruitingNCT03771105Early Phase 11 country
- Effective Dosing of Burosumab in XLHRecruitingNCT071835791 country
- Protocolised Management of Phosphate Replacement TrialNot yet recruitingNCT07288944Not applicable
- Enteral Supplementation With Sodium Dihydrogen Phosphate and Disodium Hydrogen Phosphate Granules for the Treatment of Hypophosphatemia.RecruitingNCT07233889Not applicable1 country
- Effect of Hypophosphatemia on Neuro-excursion Efficiency During Mechanical Ventilator WeaningRecruitingNCT067546701 country
- Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate MetabolismNot yet recruitingNCT068266641 country
- IV Iron-induced Hypophosphatemia After RYGBRecruitingNCT06350955Phase 41 country
- Calcium-phosphate Complications Induced by IV Iron Supplementation in Patients With Rendu-Osler DiseaseRecruitingNCT055446691 country
- Risk Factors for Refeeding Syndrome in the Surgical Intensive Care UnitRecruitingNCT060541391 country
- BGJ398 for the Treatment of Tumor-Induced OsteomalaciaTerminatedNCT03510455Phase 21 country
- X-linked Hypophosphatemia Disease Monitoring ProgramActive, not recruitingNCT036515056 countries
- The Efficacy and Safety of Diluted Oral Phosphate Enema Versus Intravenous Sodium Glycerophosphate in The Treatment of Hypophosphatemia in ICU PatientsCompletedNCT06651892Phase 2/31 country
- Phosphate Urine Excretion in Critically Ill PatientsActive, not recruitingNCT067793311 country
- Metabolic Pathway Analysis in Intensive Care Unit Patients With Refeeding SyndromeCompletedNCT063445463 countries
- Validation of the GIDS and Description of Phosphate DisordersCompletedNCT059097221 country
- Effects of Treatments for Anemia and Iron Deficiency on the Electrolyte Balance in Lung Transplant Recipients: A Special Focus on HypophosphatemiaActive, not recruitingNCT061122361 country
- Newborn Phosphocalcic Metabolism After Intravenous Iron Administration During PregnancyCompletedNCT061082581 country
- Ferric Carboxymaltose With or Without Phosphate Substitution for the Treatment of Iron Deficiency or Iron Deficiency AnemiaCompletedNCT05098249Phase 41 country
- Study of the Inappropriate Secretion of FGF23 in Patients Followed in Hospital in a Context of HypophosphatemiaCompletedNCT048466471 country
- Biomarker for Cystinosis Disease: BioCystinosis (BioCystinosis)WithdrawnNCT028375233 countries
- FGF23 and Angiotensin-(1-7) in Hypophosphatemia (GAP)CompletedNCT034899931 country
- Dental Implants in Patients With X-linked HypophosphatemiaStatus unknownNCT038799151 country
- Comparing Metabolic Characteristics of Persistent Critically Ill Non-COVID and COVID-19 PatientsCompletedNCT050261511 country
- Using Cinacalcet to Treat the Hypophosphatemia of Early Kidney TransplantTerminatedNCT01011114Not applicable1 country
- Hypophosphatemia and BronchiolitisStatus unknownNCT048146411 country
- Levels of 'Hypophosphatemia Affect Outcome of Septic Patients in ICUStatus unknownNCT04519762Phase 4
- Investigation of Hypophosphataemia Following Intravenous IronStatus unknownNCT045027841 country
- Hypophosphatemia Deleteriously Affects Outcome of Septic Shock Patients Admitted to ICUCompletedNCT044551131 country
- Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic RicketsCompletedNCT00417612Phase 31 country
- Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose vs Ferric Carboxymaltose in Subjects With Iron Deficiency AnaemiaCompletedNCT03238911Phase 31 country
- Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose or Ferric Carboxymaltose in Subjects With Iron Deficiency AnaemiaCompletedNCT03237065Phase 31 country
- Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic RicketsCompletedNCT03581591Phase 31 country
- Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot Project.CompletedNCT02233322Not applicable1 country
- The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck CancerCompletedNCT01845922Not applicable1 country
- Simplified Regional Citrate Anticoagulation Protocols for CVVH, CVVHDF and SLED: a Pilot StudyStatus unknownNCT039764401 country
- Hypophosphatemia as a Predictor in Surgical Resuscitation SepsisCompletedNCT037408021 country
- Treatment of Autonomous Hyperparathyroidism in Post Renal Transplant RecipientsCompletedNCT00975000Phase 311 countries
- Hypophosphatemia as a Predictive Marker of Mortality During Sepsis in ICUCompletedNCT035290581 country
- Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic OsteomalaciaCompletedNCT000997621 country
- Effect of the Consumption of Ferric Hydroxide Adipate on Urinary Phosphorus Excretion.CompletedNCT01991574Early Phase 11 country
- Observing the Changes of Fibroblast Growth Factor 23 in Patients of Tumor Induced OsteomalaciaStatus unknownNCT016603081 country
- FGF-23 Suppressibility by CalcitoninCompletedNCT00688077Not applicable1 country
- Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia.TerminatedNCT00622479Phase 11 country