ClinicalTrials.gg
RecruitingNCT06824454Updated Jun 11, 2026

Evaluation of Dipyridamole in Preventing Post-Transplant Hypophosphatemia in Kidney Transplant Recipients

A Phase 2 interventional study of Dipyridamole 75 MG in Hypophosphatemia and Kidney Transplantation, sponsored by Stanford University. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-11.

Sponsored by Stanford University · Phase 2, Interventional, and Treatment

From the registry’s dates

  • Started May 2025; still recruiting 1 year 5 months later.
Phase
Phase 2
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The primary goal is to determine if Dipyridamole can improve serum phosphate levels and reduce the need for phosphate supplementation.

02

Conditions studied

  • Hypophosphatemia
  • Kidney Transplantation

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Keywords

  • Post-kidney transplant care
  • Dipyridamole
  • Renal phosphate loss
  • Serum phosphate levels
  • Phosphate supplementation
  • Transplant graft function
  • Kidney transplant complications
03

In context

Hypophosphatemia

53 studies on the registry are indexed under Hypophosphatemia; 16 are open to participants now.

This study's planned enrollment of 90 is above the median of 46 across 26 interventional studies indexed under Hypophosphatemia.

Browse Hypophosphatemia studies →

Lead sponsor

Stanford University is the lead sponsor of 2,168 studies on the registry; 431 are open to participants now.

Of its 267 completed or terminated interventional studies of FDA-regulated products, 207 (78%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adult kidney transplant patients.
  • No known to Dipyridamole

Exclusion criteria

Exclusion Criteria:

  • to Dipyridamole.
  • Patients with delayed graft function (defined as the need for dialysis within seven days post-transplantation).
  • Patients requiring Plavix, direct oral anticoagulants (DOACs), or Coumadin.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
90 participants (estimated)

Study arms

  • Experimental
    Treatment Group

    Participants receive Dipyridamole in addition to standard post-transplant care.

    Drug: Dipyridamole 75 MG

  • No intervention
    Control Group

    Participants in this group will receive standard post-transplant care without Dipyridamole.

Interventions

  • Dipyridamole administered three times daily when serum phosphorus levels fall below 4 mg/dL. The drug is used off-label for this study to manage hypophosphatemia in kidney transplant recipients.

06

What researchers measure

Primary outcomes

  1. Change in Serum Phosphorus Levels After Dipyridamole Administration

    This study will evaluate the effectiveness of Dipyridamole in increasing serum phosphorus levels in kidney transplant recipients with hypophosphatemia.

    Time frame: Baseline, 1 week, 4 weeks, 8 weeks, 12 weeks, and after stopping medicatio

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 11, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06824454
Responsible party
Stephan Busque (Professor of Surgery (Abdominal Transplantation), Stanford University) — Principal investigator
First posted
Feb 13, 2025
Start date
May 15, 2025
Primary completion
May 2027 (estimated)
Completion
May 2027 (estimated)
Last update
Jun 11, 2026

Study contacts

Stephan Busque, MD
principal investigator · Stanford University

Oversight

Data monitoring committee
No
FDA-regulated drug
Yes
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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