Hypesthesia clinical trials
The registry lists 47 studies for Hypesthesia across more than 10 countries. 12 are recruiting or about to start. 16 of them are mainly about Hypesthesia (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-21.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Novalar Pharmaceuticals, Inc. (4) · Bernardino Clavo, MD, PhD (2) · VM Therapeutics LLC (1) · Ukrainian Society of Regional Anesthesia and Pain Therapy (1) · Columbia Northwest Pharmaceuticals (1) · Ottawa Hospital Research Institute (1) · University of Utah (1) · Boston Children's Hospital (1)
What is being tested here
Drugs under test in Hypesthesia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Phentolamine | 0 | 2 | 4 |
| Bupivacaine | 0 | 0 | 1 |
| Lidocaine | 0 | 0 | 1 |
| Donaperminogene seltoplasmid | 0 | 0 | 1 |
| Fingolimod | 0 | 0 | 1 |
| Minocycline | 0 | 0 | 1 |
| Carvedilol | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Vitamin B Complex for Inferior Alveolar Nerve Paresthesia Recovery · University of Sao Paulo
- Dec 2026Observational Study on the Treatment of Trigeminal Neuralgia by Radiosurgery · Centre Hospitalier Princesse Grace
- Jun 2027Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) · VM Therapeutics LLC
- Oct 2027Vacuum Therapy for the Treatment of Penile Numbness/Sensory Changes · Ottawa Hospital Research Institute
Who these studies take
Of the 9 Hypesthesia studies recruiting now, 7 (78%) set no upper age limit and 1 (11%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 1 (11%) for men only; 2 (22%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 8 (89%) | 9 (100%) |
| 30 | 8 (89%) | 9 (100%) |
| 40 | 8 (89%) | 9 (100%) |
| 50 | 8 (89%) | 9 (100%) |
| 65 | 7 (78%) | 8 (89%) |
| 75 | 7 (78%) | 8 (89%) |
| 85 | 6 (67%) | 7 (78%) |
Across all 47 studies, recruiting or not: 34% stop at 75 or younger and 23% at 65; 11% take children; 6% are for women only and 9% for men only; 28% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypesthesia studies take
Of 17 interventional studies with no phase under Hypesthesia, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 21 mo6–38 · 17 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 47 of 47. search them.
- Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)RecruitingNCT07072468Phase 21 country
- Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).RecruitingNCT06799351Phase 2/31 country
- Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy PatientsRecruitingNCT060942571 country
- Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral NeuropathyRecruitingNCT06706544Phase 2/31 country
- Vitamin B Complex for Inferior Alveolar Nerve Paresthesia RecoveryNot yet recruitingNCT07592897Phase 4
- Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in UkraineRecruitingNCT07380789Not applicable1 country
- Vacuum Therapy for the Treatment of Penile Numbness/Sensory ChangesRecruitingNCT07171567Early Phase 11 country
- Neurosensorial Disorder and Pain in Oral Cavity and Oropharynx Cancer Traited Patients (OCAPA)RecruitingNCT04673981Not applicable1 country
- Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound Versus Nerve Conduction Studies (NCS)Not yet recruitingNCT06926777Not applicable1 country
- Observational Study on the Treatment of Trigeminal Neuralgia by RadiosurgeryRecruitingNCT056772431 country
- Peer Support for Patients With Diabetic Foot UlcersRecruitingNCT06004219Not applicable1 country
- Effects of Cervical Stabilization Exercises and Vibration Application in Individuals With Parkinson's DiseaseNot yet recruitingNCT05837715Not applicable
- Neuroma-Associated Pain Management After Combat-Related Trauma in UkraineCompletedNCT07416448Not applicable1 country
- Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel SyndromeSuspendedNCT03722303Early Phase 11 country
- Multimodal Haptic Feedback for Plantar Sensory SubstitutionCompletedNCT06232512Not applicable1 country
- Lidocaine Versus Bupivacaine in Orthognathic SurgeryCompletedNCT06450028Phase 41 country
- Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA)CompletedNCT07514598Not applicable1 country
- Effects of Exercises and Electrical Current Application Aiming to Strengthen Neck and Shoulder Blades Muscles on Symptoms of a Pinched Nerve in the NeckCompletedNCT07375823Not applicable1 country
- Comparison of the Results of Biostimulation Treatment of Inferior Alveolar Nerve Injury Using Nd:YAG and Diode Lasers With Different Wavelengths.CompletedNCT07416006Not applicable1 country
- Effects of Contemporary Cycling Saddle Designs on Penile Transcutaneus Oxygen and Carbon Dioxide Levels in Elite Road Cyclists Riding on a Stationary TrainerCompletedNCT05887193Not applicable1 country
- Safety and Efficacy Study for the Treatment of Painful Diabetic NeuropathyCompletedNCT01475786Phase 22 countries
- Cybersickness in Different Multisensory Conditions in Virtual RealityCompletedNCT05534880Not applicable1 country
- Fingolimod in Treating Patients With Chemotherapy-Induced NeuropathyCompletedNCT03943498Early Phase 11 country
- Stroking Versus Ergon Technique in Pregnant WomenStatus unknownNCT05665413Not applicable1 country
- Feasibility Study for Electroacupuncture for Chemotherapy- Induced Peripheral Neuropathy (CIPN)CompletedNCT04092764Not applicable1 country
- Can rTMS Enhance Somatosensory Recovery After Stroke?CompletedNCT02811913Not applicable1 country
- Effect of Topical Lidocaine on Warm and Cold Sensation in Healthy IndividualsStatus unknownNCT04865185Not applicable1 country
- Non-surgical Intervention for Carpal Tunnel SyndromeCompletedNCT03360344Not applicable1 country
- Phase II Study of Minocycline for Reducing Symptom Burden in Colorectal PatientsCompletedNCT01906008Phase 21 country
- Comparison of Midline With Lateral Skin Incision in Simultaneous Bilateral TKAStatus unknownNCT04240847Not applicable1 country
- Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPNTerminatedNCT03206216Not applicable1 country
- Learning Oriented Physiotherapy - a New ApproachCompletedNCT02194036Not applicable1 country
- Antiseptic and Analgesic Action Acmella Oleracea Skin: Randomized Clinical TrialCompletedNCT02792972Not applicable
- Efficacy of Acupuncture in Prevention of Chemotherapy Induced Peripheral Neuropathy - a Pilot StudyStatus unknownNCT02744274Phase 31 country
- Geranium Oil and Its Components for the Relief of Numbness-OB 100CompletedNCT01022437Not applicable1 country
- Percutaneous Versus Open Plate Fixation of Diaphyseal Clavicle FracturesCompletedNCT014057031 country
- Clinical Study for the Treatment of Peripheral Nerve Defects With NeuromaixCompletedNCT01884376Not applicable1 country
- Elective Neurectomy During Inguinal Hernia RepairCompletedNCT00492804Phase 21 country
- Symptom Management Program for Hemodialysis PatientsCompletedNCT01620580Not applicable1 country
- Post-bariatric Abdominoplasty: Skin Sensation EvaluationCompletedNCT00831610Not applicable1 country
- A Human Experimental Model for Neuropathic Pain Using Combined Application of Capsaicin and Local AnestheticsCompletedNCT01540877Not applicable1 country
- Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD)Status unknownNCT01221792Phase 21 country
- Sensory Function After Wound Instillation of CapsaicinCompletedNCT005831801 country
- Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Mandibular ProceduresCompletedNCT00309361Phase 31 country
- Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary ProceduresCompletedNCT00309335Phase 31 country
- Study of NV-101 for Safety and Efficacy in Pediatric Dental Patients Undergoing ProceduresCompletedNCT00309322Phase 21 country
- Safety and Efficacy Study of NV-101 in Dental PatientsCompletedNCT00154167Phase 21 country