An interventional study of Application of capsaicin 0.6% and Application of local anesthetics (EMLA plaster) in Ipsi- and Contralateral Hypoesthesia, sponsored by Ruhr University of Bochum. Completed at 1 site in Germany. Open to participants aged 18 Years to 90 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-02-29.
Sponsored by Ruhr University of Bochum · Not applicable, Interventional, and Basic science
Main of the present study was to develop a model of concomitant C-fibre block and sensitization eliciting spontaneous pain as well applying topical capsaicin and local anesthetics (LA) to examine the sensory alterations after combined C-fiber block and sensitization in both different application orders (sensitization of blocked C-fibers and block of sensitized C-fibers), compared to each of both mechanisms alone. Thereby, we expect stronger sensory changes during the combined substance application than during the monoapplication. We expect also contralateral sensory alterations mirroring the changes on the intervention site after the combined capsaicin and LA application, being stronger than after sensitization alone absent after C-fiber block alone.
47 studies on the registry are indexed under Hypesthesia; 12 are open to participants now.
This study's enrollment of 28 is below the median of 50 across 43 interventional studies indexed under Hypesthesia.
Browse Hypesthesia studies →Ruhr University of Bochum is the lead sponsor of 126 studies on the registry; 3 are open to participants now.
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Contraception
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Hypersensitivity
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application of 0.6%
Procedure: Application of capsaicin 0.6%
application of EMLA
Procedure: Application of local anesthetics (EMLA plaster)
application of 1. capsaicin 0.6% and 2. EMLA
Procedure: Application of 1 capsaicin 0.6% and 2. EMLA
application of 1. EMLA and 2. capsaicin 0.6%
Procedure: Application of 1. EMLA and 2. capsaicin 0.6%
topical application of 0.6% capsaicin on the volar forearm
topical application of EMLA on the volar forearm
topical application of 1. 0.6% capsaicin and 2. EMLA on the volar forearm
topical application of 1. EMLA and 2. 0.6% capsaicin on the volar forearm
grade of the ipsi- and contralateral hypoesthesia
Time frame: 6 months
area of the ipsi- and contralateral hypoesthesia
Time frame: 6 months
The record gives a start of Apr 2011 and a primary completion of Sep 2011. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Feb 2012. You cannot join it, but the record below documents what was studied.
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