Huntington Disease: all 290 studies
Page 1 of 3. Open to participants first (49), then studies with results posted, then the rest; newest registration first within each.
- Pridopidine Phase 3 Study in Huntington's DiseaseRecruitingNCT07609108Phase 3
- An Extension of SKY-0515 in Participants With Huntington's DiseaseEnrolling by invitationNCT07537075Phase 2/3
- A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's DiseaseRecruitingNCT07536061Phase 1
- Mass Balance Study of [14C] LPM3770164 in Healthy ParticipantsNot yet recruitingNCT07516899Phase 1
- Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's DiseaseRecruitingNCT07513844Not applicable
- Safety and Tolerability Study of Human Neural Stem Cells for Huntington's DiseaseRecruitingNCT07451613Phase 1/2
- Autobiographical Memory, Future Thought, and Eye Movements in Huntington's DiseaseNot yet recruitingNCT07409597Not applicable
- Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's DiseaseRecruitingNCT07378644Phase 2/3
- A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's DiseaseRecruitingNCT07326709Phase 3
- Multi-Modal Digital Monitoring of Disease Symptoms Huntington's DiseaseNot yet recruitingNCT07315984
- Evaluation of Three Tests to Assess Social Cognition in Huntington DiseaseRecruitingNCT07253038
- Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic PathologyRecruitingNCT07136844Not applicable
- Digital Measures for Clinical Trial Endpoints in Huntington's DiseaseRecruitingNCT07010705
- Transcranial Static Magnetic Stimulation (tSMS) in Huntington's Disease (HD)Not yet recruitingNCT06976983Not applicable
- Huntington's Disease Biobank: Advancing Remote Monitoring and Deep PhenotypingRecruitingNCT06941662
- The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's DiseaseRecruitingNCT06853743Phase 2
- Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's DiseaseRecruitingNCT06843252Not applicable
- A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's DiseaseRecruitingNCT06826612Phase 1/2
- ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared CriteriaRecruitingNCT06782230
- Hinting Task for Huntington's DiseaseRecruitingNCT06774443
- Huntington's Disease and PainNot yet recruitingNCT06693466
- iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009RecruitingNCT06634628Early Phase 1
- Early Biomarkers in Premanifest Huntington's Disease Gene Carriers: a Pilot StudyRecruitingNCT06626308Not applicable
- A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's DiseaseRecruitingNCT06585449Phase 1
- Cognitive Assessment Tools for Huntington's Disease.RecruitingNCT06546488
- FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare DiseasesRecruitingNCT06539169
- Longitudinal Endpoint Assessment of Disease Burden in HDRecruitingNCT06475898
- Gut Microbiomes in HDRecruitingNCT06448546
- Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)RecruitingNCT06414967Not applicable
- Long-term Study to Evaluate Safety and Tolerability of Valbenazine in Participants With Chorea Associated With Huntington Disease in CanadaEnrolling by invitationNCT06312189Phase 3
- NYSCF Scientific Discovery BiobankRecruitingNCT06203106
- Long Term Follow-up Grafted Huntington's Disease PatientsNot yet recruitingNCT06194006Not applicable
- Development of Non-Invasive Prenatal Diagnosis for Single Gene DisordersRecruitingNCT06147414
- Efficacy and Safety of NestaCell® in Huntington's DiseaseNot yet recruitingNCT06097780Phase 3
- Extracellular Vesicles for HDRecruitingNCT06082713
- Striatum and Hippocampus on Different Time ScalesRecruitingNCT05943054Not applicable
- Benchmarking Integrated Care for People Living With Huntington's Disease in EnglandRecruitingNCT05828992
- A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HDRecruitingNCT05822908Phase 1/2
- Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease ProgressionRecruitingNCT05808153Not applicable
- Prospective Single-Timepoint Huntington's Disease Biospecimen Collection StudyRecruitingNCT05773196
- A Randomised Controlled Trial, of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion CarriersRecruitingNCT05509153Phase 2
- Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.RecruitingNCT05360082Not applicable
- Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's DiseaseRecruitingNCT05326451Not applicable
- Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's DiseaseRecruitingNCT04478734Phase 2
- Study of BDNF Pathway Biomarkers in the Cerebrospinal Fluid in Patients With Huntington's DiseaseRecruitingNCT04012411Not applicable
- IMarkHD: in Vivo Longitudinal Imaging of HD PathologyRecruitingNCT03434548
- Retinal Imaging in Neurodegenerative DiseaseRecruitingNCT03233646
- HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's DiseaseRecruitingNCT02855476
- Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease CohortRecruitingNCT01574053
- Real World Effectiveness and Safety of Deutetrabenazine in Adult Chinese Participants With Huntington's Disease (HD) Chorea in ChinaCompletedNCT07601516Phase 4Results posted
- A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's DiseaseTerminatedNCT05655520Phase 3Results posted
- Efficacy and Safety on SOM3355 in Huntington's Disease ChoreaCompletedNCT05475483Phase 2Results posted
- 28-Day Study of SAGE-718 on Functioning Capacity in Participants With Huntington's DiseaseCompletedNCT05358821Phase 2Results posted
- A Study to Evaluate the Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD)CompletedNCT05358717Phase 2Results posted
- Measurement and Modification of Threat Interpretation Bias in Neurodegenerative Movement Disorders (Aims 2 & 3)CompletedNCT05126862Not applicableResults posted
- A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam in Early Manifest Huntington's DiseaseTerminatedNCT05111249Phase 2Results posted
- A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)CompletedNCT05107128Phase 2Results posted
- Study of WVE-003 in Patients With Huntington's DiseaseCompletedNCT05032196Phase 1/2Results posted
- Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's DiseaseTerminatedNCT04617860Phase 1/2Results posted
- Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120101 in Patients With Huntington's DiseaseTerminatedNCT04617847Phase 1/2Results posted
- PRidopidine's Outcome On Function in Huntington Disease, PROOF- HDCompletedNCT04556656Phase 3Results posted
- An Open Label Study of ANX005 in Participants With, or at Risk for, Manifest Huntington's DiseaseCompletedNCT04514367Phase 2Results posted
- Risperidone for the Treatment of Huntington's Disease Involuntary MovementsCompletedNCT04201834Phase 2Results posted
- Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington DiseaseCompletedNCT04102579Phase 3Results posted
- A Study to Investigate the Pharmacokinetics and Pharmacodynamics of RO7234292 (RG6042) in CSF and Plasma, and Safety and Tolerability Following Intrathecal Administration in Patients With Huntington's DiseaseCompletedNCT04000594Phase 1Results posted
- Within Subject Crossover Study of Cognitive Effects of Neflamapimod in Early-Stage Huntington DiseaseTerminatedNCT03980938Phase 2Results posted
- Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's DiseaseCompletedNCT03854019Phase 3Results posted
- An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Participants Who Participated in Prior Roche and Genentech Sponsored StudiesCompletedNCT03842969Phase 3Results posted
- A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's DiseaseCompletedNCT03761849Phase 3Results posted
- Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest Stage I or Stage II Huntington's DiseaseCompletedNCT03664804Phase 1Results posted
- Safety and Efficacy of Fenofibrate as a Treatment for Huntington's DiseaseCompletedNCT03515213Phase 2Results posted
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (ISIS 443139) in Huntington's Disease Patients Who Participated in Prior Investigational Studies of RO7234292 (ISIS 443139)CompletedNCT03342053Phase 2Results posted
- Dose-response Evaluation of the Cellavita HD Product in Patients With Huntington's DiseaseCompletedNCT03252535Phase 2Results posted
- Safety and Tolerability of WVE-120102 in Patients With Huntington's DiseaseTerminatedNCT03225846Phase 1/2Results posted
- Safety and Tolerability of WVE-120101 in Patients With Huntington's DiseaseTerminatedNCT03225833Phase 1/2Results posted
- A Study to Evaluate Sigma-1 and Dopamine-2 Receptor Occupancy by Pridopidine in the Human Brain of Healthy Volunteers and in Patients With Huntington's DiseaseCompletedNCT03019289Phase 1Results posted
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's DiseaseCompletedNCT02519036Phase 1/2Results posted
- Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's DiseaseCompletedNCT02507284Phase 2Results posted
- A Study Evaluating if Pridopidine is Safe, Efficacious, and Tolerable in Patients With Huntington's DiseaseTerminatedNCT02494778Phase 2Results posted
- Electronic-health Application To Measure Outcomes REmotely Clinical TrialCompletedNCT02418546Not applicableResults posted
- Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021TerminatedNCT02342548Phase 2Results posted
- Study Exploring Safety, Pharmacokinetic and Pharmacodynamic of BN82451 in Male Huntington's Disease PatientsTerminatedNCT02231580Phase 2Results posted
- A Clinical Study in Participants With Huntington's Disease (HD) to Assess Efficacy and Safety of Three Oral Doses of LaquinimodCompletedNCT02215616Phase 2Results posted
- Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's DiseaseCompletedNCT02197130Phase 2Results posted
- A Phase 2, to Evaluating the Safety and Efficacy of Pridopidine Vs Placebo for Symptomatic Treatment in Patients With Huntington's DiseaseCompletedNCT02006472Phase 2Results posted
- Alternatives for Reducing Chorea in Huntington DiseaseCompletedNCT01897896Phase 3Results posted
- Proof of Concept of an Anaplerotic Study Using Brain Phosphorus Magnetic Resonance Spectroscopy in Huntington DiseaseCompletedNCT01882062Phase 2Results posted
- Effect of Tetrabenazine on Stroop Interference in HDCompletedNCT01834911Phase 4Results posted
- Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's DiseaseCompletedNCT01806896Phase 2Results posted
- First Time Use of SD-809 in Huntington DiseaseCompletedNCT01795859Phase 3Results posted
- The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's DiseaseCompletedNCT01735981Not applicableResults posted
- Effect of PBT2 in Patients With Early to Mid Stage Huntington DiseaseCompletedNCT01590888Phase 2Results posted
- Impact of Xenazine(Tetrabenazine)on Gait and Functional Activity in Individuals With Huntington's DiseaseCompletedNCT01451463Results posted
- Creatine Safety & Tolerability in Huntington's DiseaseCompletedNCT01412151Phase 2Results posted
- Open-label Extension Study of Pridopidine (ACR16) in the Symptomatic Treatment of Huntington DiseaseCompletedNCT01306929Phase 2Results posted
- A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug UsersCompletedNCT00975481Phase 1Results posted
- Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL)CompletedNCT00920699Phase 2Results posted
- A Study of Pridopidine (ACR16) for the Treatment of Participants With Huntington's DiseaseCompletedNCT00724048Phase 2Results posted
- Examination of Quantitative Electroencephalographic (QEEG) Biomarkers in Huntington's DiseaseCompletedNCT00670709Results posted
- A Study of Treatment With Pridopidine (ACR16) in Participants With Huntington's DiseaseCompletedNCT00665223Phase 3Results posted