Pfizer: Huntington Disease trials

The registry lists 16 Huntington Disease studies with Pfizer as lead sponsor. 0 are open to participants now and 4 have results posted.

Phase 1 10Phase 2 5Phase 3 2(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021TerminatedNCT02342548Phase 2Results posted
• Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's DiseaseCompletedNCT02197130Phase 2Results posted
• Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's DiseaseCompletedNCT01806896Phase 2Results posted
• A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug UsersCompletedNCT00975481Phase 1Results posted
• An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington DiseaseTerminatedNCT01085266Phase 3
• A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The SkinCompletedNCT00990613Phase 1
• A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)CompletedNCT00988624Phase 1
• A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 MetabolizersCompletedNCT00931073Phase 1
• A Safety and Efficacy Study of Dimebon in Patients With Huntington DiseaseCompletedNCT00920946Phase 3
• Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy SubjectsCompletedNCT00831506Phase 1
• A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy SubjectsCompletedNCT00827034Phase 1
• A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy SubjectsCompletedNCT00825084Phase 1
• A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal FunctionCompletedNCT00824590Phase 1
• A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of DextromethorphanCompletedNCT00788047Phase 1
• A Study of the Novel Drug Dimebon in Patients With Huntington's DiseaseCompletedNCT00497159Phase 2
• Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's DiseaseCompletedNCT00387270Phase 1/2