Hemolytic-Uremic Syndrome clinical trials
The registry lists 28 studies for Hemolytic-Uremic Syndrome across more than 10 countries. 7 are recruiting or about to start. 16 of them are mainly about Hemolytic-Uremic Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its narrower condition Atypical Hemolytic Uremic Syndrome too: 70 studies, 19 open.
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Who runs them
Inmunova S.A. (3) · University Hospital, Tours (2) · Assiut University (2) · University of Calgary (2) · University Children's Hospital, Zurich (1) · Universitätsklinikum Hamburg-Eppendorf (1) · University of Alabama at Birmingham (1) · Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia (1)
What is being tested here
Drugs under test in Hemolytic-Uremic Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026Complement Prospective Evaluation of Thrombotic Microangiopathy on Endothelium · Maastricht University Medical Center
- Aug 2027Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection · University of Calgary
Who these studies take
Of the 6 Hemolytic-Uremic Syndrome studies recruiting now, 4 (67%) set no upper age limit and 2 (33%) stop at 75 or younger. 2 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (33%) | 2 (33%) |
| 18 | 5 (83%) | 5 (83%) |
| 30 | 4 (67%) | 4 (67%) |
| 40 | 4 (67%) | 4 (67%) |
| 50 | 4 (67%) | 4 (67%) |
| 65 | 4 (67%) | 4 (67%) |
| 75 | 4 (67%) | 4 (67%) |
| 85 | 4 (67%) | 4 (67%) |
Across all 28 studies, recruiting or not: 50% stop at 75 or younger and 50% at 65; 75% take children; 4% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 28 of 28. search them.
- Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer TreatmentRecruitingNCT010873331 country
- Hyperhydration in Children With Shiga Toxin-Producing E. Coli InfectionRecruitingNCT05219110Not applicable2 countries
- Efficacy of INM004 in Children With STEC-HUSRecruitingNCT06389474Phase 39 countries
- Complement Prospective Evaluation of Thrombotic Microangiopathy on EndotheliumRecruitingNCT047451951 country
- Prevalence of Hemolytic Uremic Syndrome (HUS) in PediatricsNot yet recruitingNCT07171749
- Study of Patients With Thrombotic Microangiopathy Associated With Mitomycin C, Treated or Not With EculizumabRecruitingNCT060983781 country
- French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy"RecruitingNCT059912451 country
- Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHUCompletedNCT02205541Phase 31 country
- New Analytic Tools for aHUS and C3G DiagnosisActive, not recruitingNCT05985122Not applicable1 country
- US Post-Marketing Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITI)TerminatedNCT041252901 country
- Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU)CompletedNCT04859608Phase 31 country
- A Study to Assess Safety, Efficacy, and Pharmacokinetics of INM004 in Pediatric Patients With STEC-HUSCompletedNCT05569746Phase 21 country
- Study of 'Vascular Competence' Profile and Endothelial Activation in the Hemolytic Uremic Syndrome in Children and AdultsCompletedNCT02904863Not applicable1 country
- Phase 2/3 Study to Evaluate PK, Safety & Efficacy of INM004 in STEC Positive Pediatric Patients for Prevention of HUSTerminatedNCT04132375Phase 2/31 country
- Observational Study of Elizaria® in aHUS PatientsCompletedNCT047498101 country
- Erythropoietin in Hemolytic Uremic SyndromeCompletedNCT03776851Phase 41 country
- Shiga Toxin Producing Escherichia Coli (STEC) Volume ExpansionWithdrawnNCT03275792Phase 11 country
- Usefulness of a Diagnostic Algorithm to Diagnose Thrombotic Microangiopathies in PregnancyStatus unknownNCT035809411 country
- The Role of Endothelium Dysfunction in Progression of CKD (Chronic Kidney Disease) After AKI (Acute Kidney Injury)CompletedNCT003583061 country
- Outcame of Cases With Hemolytic Uremic Syndrome Attending Assiut University Child HospitalStatus unknownNCT03690024
- Phase III Randomized Study of SYNSORB Pk in Children With E. Coli-Associated Hemolytic Uremic SyndromeTerminatedNCT00004465Phase 32 countries
- Haemolytic Uraemic Syndrome in Childhood: Clinical, Cognitive and Psychological AspectsCompletedNCT016665481 country
- International Registry and Biorepository for TMA(Thrombotic Microangiopathy)TerminatedNCT005932291 country
- Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTXCompletedNCT00360685Not applicable1 country
- The Plasma Large-Volume Exchange RCTWithdrawnNCT01433003Phase 31 country
- Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4CompletedNCT014062881 country
- Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic ColitisCompletedNCT01561248Not applicable1 country
- Rituximab in Patients With Relapsed or Refractory TTP-HUSStatus unknownNCT00531089Phase 21 country