Heat Stress Disorders clinical trials
The registry lists 118 studies for Heat Stress Disorders across more than 10 countries. 42 are recruiting or about to start. 67 of them are mainly about Heat Stress Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 2 narrower conditions too, such as Hyperthermia: 365 studies, 108 open.
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Status
Who runs them
University of Ottawa (30) · Aditi Bunker (7) · State University of New York at Buffalo (5) · Petros Dinas (4) · Penn State University (4) · Aga Khan University (4) · United States Army Research Institute of Environmental Medicine (3) · University of Texas Southwestern Medical Center (2)
What is being tested here
Drugs under test in Heat Stress Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension · Vanderbilt University Medical Center
- Dec 2026Role of Menopause in Thermoregulation · Penn State University
- Dec 2026Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain · University of Ottawa
- Feb 2027Effects of Hot Baths Prior or After a Damaging Protocol on Muscle Function and HSP70 Expression · Centre Hospitalier Universitaire, Amiens
- Feb 2027Identification of Critical Thermal Environments for Aged Adults · Penn State University
- Mar 2027Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat · University of Northern Iowa
- Mar 2027Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat · State University of New York at Buffalo
- Apr 2027Exercise Intensity and Heat Responses in Children and Youth · University of Ottawa
- Apr 2027Ambient Temperature and Thermoregulation During Exercise in Children and Youth · University of Ottawa
- Apr 2027Efficacy of Electric Fans in Children During Heat Waves · University of Ottawa
Who these studies take
Of the 30 Heat Stress Disorders studies recruiting now, 8 (27%) set no upper age limit and 18 (60%) stop at 75 or younger. 6 (20%) take children under 18. 4 (13%) are for women only and 3 (10%) for men only; 22 (73%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (20%) | 6 (20%) |
| 18 | 21 (70%) | 18 (60%) |
| 30 | 18 (60%) | 15 (50%) |
| 40 | 15 (50%) | 13 (43%) |
| 50 | 13 (43%) | 13 (43%) |
| 65 | 14 (47%) | 15 (50%) |
| 75 | 12 (40%) | 12 (40%) |
| 85 | 11 (37%) | 10 (33%) |
Across all 118 studies, recruiting or not: 55% stop at 75 or younger and 49% at 65; 12% take children; 8% are for women only and 17% for men only; 86% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Heat Stress Disorders studies take
Of 77 interventional studies with no phase under Heat Stress Disorders, half reached primary completion within 14 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 14 mo5–27 · 77 studies | — | 14 mo5–27 · 77 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
- Progressive Heat Exposure and Physiological StrainNov 12, 2026NCT07847437
Newly registered2
- Heat and Mental Health - PART 2Oct 29, 2026NCT07903896
- Testing Interventions to Mitigate the Health Impact of Heatwaves on Primary School Children in Climate-vulnerable Districts of Bangladesh.Oct 16, 2026NCT07877935
Studies
Recruiting first, then most recently updated. Showing 50 of 118. Browse all 118 → or search them.
- Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological StrainRecruitingNCT07664462Not applicable1 country
- Progressive Heat Exposure and Physiological StrainRecruitingNCT07847437Not applicable1 country
- Exercise Intensity and Heat Responses in Children and YouthEnrolling by invitationNCT07781592Not applicable1 country
- Efficacy of Electric Fans in Children During Heat WavesRecruitingNCT07864103Not applicable1 country
- Ambient Temperature and Thermoregulation During Exercise in Children and YouthRecruitingNCT07781605Not applicable1 country
- Heat and Mental Health - PART 2RecruitingNCT07903896Not applicable1 country
- Structural Heat Adaptation and Education in Urban SettingRecruitingNCT06991543Not applicable1 country
- Testing Interventions to Mitigate the Health Impact of Heatwaves on Primary School Children in Climate-vulnerable Districts of Bangladesh.RecruitingNCT07877935Not applicable1 country
- Indoor Overheating and Physiological Strain in Older Adults With COPDNot yet recruitingNCT07852910Not applicable1 country
- Consecutive Occupational Heat Exposure With and Without Overnight CoolingRecruitingNCT07656519Not applicable1 country
- Role of Menopause in ThermoregulationRecruitingNCT06798571Phase 41 country
- Assessing the Effectiveness of Heat Adaptation Digital Messages From Primary Care Providers to Their Patients on the Change in Behaviour for Heatwave-related PreparednessRecruitingNCT07024628Not applicable1 country
- Work Design Interventions for Heat ResilienceNot yet recruitingNCT06599788Not applicable
- Work Design Interventions for Older Workers During Consecutive Days in the HeatNot yet recruitingNCT07046026Not applicable
- Structural Heat Adaptation and Education in Rural SettingRecruitingNCT06983483Not applicable1 country
- Suitability of a 26 °C Indoor Environment for Mitigating Heat Strain in Young AdultsRecruitingNCT07267598Not applicable1 country
- The Impact of Wearing the Hijab on Whole-body Heat Loss During Exercise-heat StressRecruitingNCT07174180Not applicable1 country
- Carbohydrate or Protein Drinks Before Exercise in the HeatNot yet recruitingNCT07646990Not applicable
- Efficacy and Safety of Modified ORS(Amr and Khulood ORS) in Diabetic Pilgrims During HajjNot yet recruitingNCT07618702Not applicable1 country
- Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, FijiNot yet recruitingNCT07592117Not applicable1 country
- Home-Based Heat Therapy in Spinal Cord Injury to Improve Cardiovascular HealthRecruitingNCT07317843Not applicable1 country
- Effects of Hot Baths Prior or After a Damaging Protocol on Muscle Function and HSP70 ExpressionRecruitingNCT07559344Not applicable1 country
- Heat Stress in Individuals With SchizophreniaRecruitingNCT07383324Not applicable1 country
- Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient IndividualsRecruitingNCT07510061Not applicable2 countries
- Indigenous Nutritional Supplements for Pregnancy to Improve Resilience in Environmental HeatNot yet recruitingNCT07489664Not applicable1 country
- Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the HeatRecruitingNCT07472426Not applicable1 country
- Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, MexicoNot yet recruitingNCT06834893Not applicable1 country
- Assessing the Effect of Cool Roofs on Health Using Smartwatches in Colima, MexicoNot yet recruitingNCT06831006Not applicable1 country
- Assessing the Effects of Cool Roofs on Indoor Environments and HealthRecruitingNCT06579950Not applicable5 countries
- Heat Stress Exposure Among Low-Income Residents in Bangladesh and Evaluation of Indoor InterventionsRecruitingNCT06979258Not applicable1 country
- Impact of Depression on ThermoregulationRecruitingNCT068058511 country
- Identification of Critical Thermal Environments for Aged AdultsRecruitingNCT04284397Early Phase 11 country
- Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for HeatRecruitingNCT06475339Not applicable1 country
- Beat the Heat BostonRecruitingNCT06982339Not applicable1 country
- Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine HypertensionRecruitingNCT03042988Not applicable1 country
- Biological Impacts of Rising Temperatures on Maternal, Fetal, and Newborn Health: A Cohort Study (BIRTH Cohort)RecruitingNCT069577691 country
- Aging, Beta Blockers, and Thermoregulatory ResponsesRecruitingNCT06582680Phase 41 country
- The Impact of Acute Exercise in the Heat on Breast Milk Production and Composition in Lactating WomenRecruitingNCT07036640Not applicable1 country
- Mitigating Heat Stress Among Rickshaw Drivers in BangladeshNot yet recruitingNCT06956430Not applicable
- Preparing for Heat Waves - Enhancing Human Thermophysiological ResilienceNot yet recruitingNCT06389604Not applicable
- Heat Strain Prevention in Elderly Agricultural WorkersRecruitingNCT06192069Not applicable1 country
- Over-the-Counter Antihistamines & Heat StressRecruitingNCT06217367Phase 41 country
- Influence of Indoor Humidity on Physiological Strain in Older Adults During a Simulated Heat WaveActive, not recruitingNCT06842953Not applicable1 country
- Suitability of the 26 °C Indoor Temperature Upper Limit for Older Adults: Impacts of Clothing and Daily ActivityActive, not recruitingNCT07189507Not applicable1 country
- Impact of Indoor Overheating on Physiological Strain in ChildrenActive, not recruitingNCT07261202Not applicable1 country
- Physiological Responses to Heat Stress During High-risk EventsCompletedNCT069072251 country
- Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age ChildrenCompletedNCT07643571Not applicable1 country
- Risk Factors for Exertional Heat IllnessCompletedNCT049794551 country
- Ethanol Consumption in the HeatCompletedNCT06935045Not applicable1 country
- Impact of Heat on Dual Task PerformanceCompletedNCT07629414Not applicable1 country