An interventional study of Low-Intensity Exercise in the Heat and Moderate-Intensity Exercise in the Heat in Body Temperature Changes, Heat Stress and Child Development, sponsored by University of Ottawa. Enrolling by invitation at 1 site in Canada. Open to female participants aged 9 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-10.
Sponsored by University of Ottawa · Not applicable, Interventional, and Basic science
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses. The goal of this clinical trial is to determine how exercise intensity affects thermoregulation in boys and girls aged 9-16 years compared with young adult men and women aged 20-25 years. Participants will complete three study visits in a hot environment of 36°C (degree Celcius (97°F, degree Farenheit)), performing light-, moderate-, and vigorous-intensity exercise corresponding to metabolic heat production of 120, 160, and 200 W/m² (w=watts, m=meter), respectively. During each visit, participants will complete four 15-minute bouts of exercise (i.e., bout 1, 2, 3 and 4 respectively) separated by 15-minute rest periods. Testing will be performed in a whole-body air calorimeter, a specialized chamber that precisely measures heat lost through evaporation and dry heat exchange and the amount of heat stored in the body. These measurements, together with core temperature and heart rate, will allow researchers to determine how increasing exercise intensity affects the body's ability to lose heat and whether these responses differ between children and youth and young adults.
97 studies on the registry are indexed under Body Temperature Changes; 20 are open to participants now.
This study's planned enrollment of 12 is below the median of 40 across 68 interventional studies indexed under Body Temperature Changes.
Browse Body Temperature Changes studies →University of Ottawa is the lead sponsor of 125 studies on the registry; 34 are open to participants now.
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Exclusion Criteria:
Participants will complete intermittent light-intensity exercise in a hot environment of 36°C (degree Celsius (97°F, degree Fahrenheit)). Exercise will be performed at a metabolic heat production of 120 W/m² (W=watts; m=meter) and will consist of four 15-minute exercise periods separated by 15-minute rest periods. Exercise workload will be individually adjusted to achieve the prescribed metabolic heat production.
Other: Low-Intensity Exercise in the Heat
Participants will complete intermittent moderate-intensity exercise in a hot environment of 36°C (97°F). Exercise will be performed at a metabolic heat production of 160 W/m² and will consist of four 15-minute exercise periods separated by 15-minute rest periods. Exercise workload will be individually adjusted to achieve the prescribed metabolic heat production.
Other: Moderate-Intensity Exercise in the Heat
Participants will complete intermittent vigorous-intensity exercise in a hot environment of 36°C (97°F). Exercise will be performed at a metabolic heat production of 200 W/m² and will consist of four 15-minute exercise periods separated by 15-minute rest periods. Exercise workload will be individually adjusted to achieve the prescribed metabolic heat production.
Other: Vigorous-Intensity Exercise in the Heat
Participants complete intermittent low-intensity exercise at a metabolic heat production of 120 W/m² (w=watts; m=meter) in a hot environment of 36°C (degree Celsius (97°F, degree Fahrenheit)).
Participants complete intermittent moderate-intensity exercise at a metabolic heat production of 160 W/m² in a hot environment of 36°C (97°F).
Participants complete intermittent vigorous-intensity exercise at a metabolic heat production of 200 W/m² in a hot environment of 36°C (97°F).
Core temperature
Core temperature indexed by visceral (telemetry pill) temperature
Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)
Evaporative heat loss
Evaporative heat loss as assessed using a direct air calorimeter.
Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)
Dry heat loss
Dry heat loss as assessed using a direct air calorimeter.
Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)
Whole-body total heat loss
Total heat loss (dry + evaporative) as assessed using a direct air calorimeter
Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)
Body Heat Storage
Heat stored in the body for each of the exercise bouts
Time frame: Change from start to the end for each of the four 15 minutes exercise bouts
Skin Temperature
Skin temperature measured at 8-sites (forehead, chest, scapula, upper arm, forearm, hand, thigh, calf) with mean value calculated as weighted value of 8 sites - forehead, 7%; chest, 17.5%; scapula, 17.5%, upper arm, 7%; forearm, 7%; hand, 5%; thigh, 19%; and calf, 20%.
Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)
Change in skin temperature
Skin temperature measured at 8-sites (forehead, chest, scapula, upper arm, forearm, hand, thigh, calf) with mean value calculated as weighted value of 8 sites - forehead, 7%; chest, 17.5%; scapula, 17.5%, upper arm, 7%; forearm, 7%; hand, 5%; thigh, 19%; and calf, 20%.
Time frame: Change from start to the end for each of the four 15 minutes exercise bouts
Heart rate
Measured continuously with chest-band device
Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)
Thermal Sensation Scale
Thermal sensation will be assessed using the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE) 7-point scale ("0=neutral to 7=extremely hot")
Time frame: End of each of the four 15 minutes exercise bouts (average of last 5 minutes)
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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