Heart Septal Defects, Ventricular clinical trials
The registry lists 59 studies for Heart Septal Defects, Ventricular across more than 10 countries. 9 are recruiting or about to start. 40 of them are mainly about Heart Septal Defects, Ventricular (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-13.
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Who runs them
University of Aarhus (4) · Abbott Medical Devices (4) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (3) · Kayseri City Hospital (2) · Asklepion Pharmaceuticals, LLC (2) · Children's Healthcare of Atlanta (2) · Chinese Academy of Medical Sciences, Fuwai Hospital (2)
What is being tested here
Drugs under test in Heart Septal Defects, Ventricular studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026An International Multicenter Study on Transcatheter Device Closure of Perimembranous Ventricular Septal Defects · Fondation Hôpital Saint-Joseph
- Jan 2027Use of TEE Derived Measurement vs Direct Measurement Under General Anesthesia in Assessment of Pressure Gradient in Peri Membranous Ventricular Septal Defect · Ain Shams University
- Jun 2027A Multimodal AI Prediction Model for Complications After Transcatheter Closure of Perimembranous VSD in Children · Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Who these studies take
Of the 6 Heart Septal Defects, Ventricular studies recruiting now, 2 (33%) set no upper age limit and 3 (50%) stop at 75 or younger. 4 (67%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (50%) | 3 (50%) |
| 18 | 4 (67%) | 4 (67%) |
| 30 | 3 (50%) | 3 (50%) |
| 40 | 3 (50%) | 3 (50%) |
| 50 | 3 (50%) | 3 (50%) |
| 65 | 3 (50%) | 3 (50%) |
| 75 | 3 (50%) | 3 (50%) |
| 85 | 2 (33%) | 2 (33%) |
Across all 59 studies, recruiting or not: 58% stop at 75 or younger and 54% at 65; 85% take children; 0% are for women only and 3% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 59. Browse all 59 → or search them.
- Investigation of Tetralogy of Fallot in NeonatesRecruitingNCT06822400Not applicable1 country
- An International Multicenter Study on Transcatheter Device Closure of Perimembranous Ventricular Septal DefectsRecruitingNCT0682363517 countries
- A Multimodal AI Prediction Model for Complications After Transcatheter Closure of Perimembranous VSD in ChildrenRecruitingNCT073756021 country
- Use of TEE Derived Measurement vs Direct Measurement Under General Anesthesia in Assessment of Pressure Gradient in Peri Membranous Ventricular Septal DefectNot yet recruitingNCT076233301 country
- IABP for MI-VSD Patients in SCAI SHOCK Stage BNot yet recruitingNCT07267884Not applicable1 country
- Bypass Clear Priming VSD Cardiopulmonary Bypass Circuit Reduce Bypass Associated Inflammation?Not yet recruitingNCT07393243Not applicable1 country
- Mechanical Complications of Acute Myocardial Infarction: a Multicenter Prospective StudyRecruitingNCT066763451 country
- Clinical Evaluation Of Ventricular Septal Defect (VSD) In Children at Sohag Univesity HospitalRecruitingNCT064924731 country
- Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative PeriodRecruitingNCT063204831 country
- Comparison of Dynamic Compliance and Airway Resistance in Pressure-Controlled Versus Volume-Controlled Ventilation in Children Undergoing Corrective Heart SurgeryCompletedNCT07754591Not applicable1 country
- Prediction Model of Spontaneous Closure of Congenital Perimembranous Ventricular Septal DefectsWithdrawnNCT077410971 country
- Early Warning of Structural Complications in Perimembranous VSDActive, not recruitingNCT076623431 country
- Improving Care for Children With Congenital Heart Disease.CompletedNCT04667455Not applicable1 country
- The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart DiseaseCompletedNCT06298344Early Phase 11 country
- A Multicenter, International, Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® PmVSD Occluder in Patients With Perimembranous Ventricular Septal DefectsActive, not recruitingNCT040344984 countries
- Regional Anesthesia Following Pediatric Cardiac SurgeryCompletedNCT05688670Phase 41 country
- Cera™ VSD Occluder Post Market Clinical Follow-upCompletedNCT059397131 country
- Immune Heterogeneity Before and After Cardiopulmonary Bypass in ChildrenCompletedNCT062141821 country
- French Observatory of Congenital Ventricular Septal Defect With Pulmonary OverloadActive, not recruitingNCT033639321 country
- Closure of Muscular Ventricular Septal Defects (VSDs) With the AMPLATZER Muscular VSD (MuVSD) Occluder - Post Approval StudyCompletedNCT00647387Not applicable2 countries
- The AMPLATZER™ Post-infarct Muscular VSD Occluder Humanitarian Device Exemption (H070005) Post Approval StudyCompletedNCT031655261 country
- A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart DefectsTerminatedNCT05253209Phase 31 country
- Lifetech KONAR MFO Post-Market Clinical Follow-Up StudyCompletedNCT044177122 countries
- Optical Tissue Identification for Myocardial ArchitectureActive, not recruitingNCT04017975Phase 21 country
- Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised ProtocolCompletedNCT01120964Phase 1/21 country
- The Effect of Transcatheter VSD Closure on Children's Appetite, Hormones and GrowthCompletedNCT052009101 country
- The Effect of Transcatheter Ventricular Septal Defect Closure on Heart Rate Variability ParametersCompletedNCT048590361 country
- Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood FlowWithdrawnNCT01825369Phase 11 country
- Cardiopulmonary Function in Adults Born With a Ventricular Septal DefectCompletedNCT036841611 country
- Closure of Muscular Ventricular Septal Defects With The AMPLATZER™ Muscular VSD OccluderCompletedNCT00583791Not applicable1 country
- A Trial to Evaluate the Safety and Efficacy of a Fully Degradable Ventricular Septal Defect (VSD) ClosureStatus unknownNCT03941691Not applicable1 country
- Closure of Perimembranous Ventricular Septal Defects With The AMPLATZER® Membranous VSD OCCLUDERCompletedNCT00578708Phase 11 country
- Safety and Effectiveness of the Nit-Occlud® Lê VSD Spiral Coil SystemCompletedNCT00390702Not applicable2 countries
- Measures to Lower the Stress Response in Pediatric Cardiac SurgeryCompletedNCT00848393Phase 21 country
- The Cardiopulmonary Effect of Inhaled Beta-2-agonists on Adult Patients Born With Ventricular Septum Defects.CompletedNCT02914652Phase 41 country
- A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and PharmacokineticsCompletedNCT01915277Phase 11 country
- Hybrid Closure of Congenital Heart DiseaseCompletedNCT02794584Not applicable
- Cardiac Function After Transcatheter VSD ClosureStatus unknownNCT031277481 country
- Acetaminophen for Oxidative Stress After Cardiopulmonary BypassCompletedNCT01228305Not applicable1 country
- Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular DiseaseCompletedNCT00005322
- Longterm Outcome After Ventricular Septal Defect ClosureCompletedNCT021384351 country
- Infant Heart Surgery: Central Nervous System Sequelae of Circulatory ArrestCompletedNCT00000470Phase 3
- Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular DiseaseCompletedNCT00005546
- Reproduction and Survival After Cardiac Defect RepairCompletedNCT00005190
- Evaluation of Latent Pulmonary Arterial Hypertension in Congenital Shunt LesionsCompletedNCT025524851 country
- Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal DefectStatus unknownNCT02644330Phase 2/31 country
- Magnet Resonance Imaging to Evaluate of Dynamic T2 Preparation Puls by Patients With Shunt or Chronic Obstructive Pulmonary DiseaseCompletedNCT024490831 country
- A Randomized Controlled Trial:Treatments on Infundibular Ventricular Septal DefectCompletedNCT02361008Not applicable1 country
- Right Bundle Branch Block After Surgical Closure of Ventricular Septal DefectCompletedNCT01480908Not applicable1 country
- Angiotensin Converting Enzyme Inhibition in Children With Mitral RegurgitationTerminatedNCT00113698Phase 32 countries