Harm Reduction clinical trials
The registry lists 55 studies for Harm Reduction across more than 10 countries. 32 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.
Status
- Recruiting
- 22
- Completed
- 13
- Not yet recruiting
- 8
- Active, not recruiting
- 8
- Enrolling by invitation
- 2
- Withdrawn
- 1
Phase
- Phase 3
- 2
- Phase 4
- 1
- Phase 2
- 1
Where
- United States
- 41
- Thailand
- 4
- France
- 2
- Georgia
- 1
- Denmark
- 1
- Armenia
- 1
Who runs them
University of Colorado, Denver (5) · Institute of HIV Research and Innovation Foundation, Thailand (4) · University of Washington (3) · Brown University (3) · NYU Langone Health (3) · University of Pittsburgh (2) · Institut National de la Santé Et de la Recherche Médicale, France (2) · University of New Mexico (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 55 — search for more.
- Clinician Practice Companion to Address Youth Substance UseNot yet recruitingNCT07725289Not applicable2 countries
- Clinical Decision Support to Increase Use of Medications for Opioid Use DisorderRecruitingNCT065262861 country
- Clinical Decision Support for Safety of Opioid TransitionsNot yet recruitingNCT065270401 country
- Teaching Health Resilience in a Hospital Setting: A Peer-led InterventionRecruitingNCT06843213Not applicable1 country
- Shelter HArm Reduction EvaluationRecruitingNCT071700721 country
- Harm Reduction ServicesRecruitingNCT05776316Not applicable1 country
- Harm Reduction Intervention for Anabolic-androgenic Steroids Users: a Randomized Controlled TrialNot yet recruitingNCT07039539Not applicable1 country
- Wellness, Alcohol, Vitals, and EmotionsRecruitingNCT06982443Not applicable1 country
- Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch UseRecruitingNCT07698470Not applicable1 country
- Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to QuitRecruitingNCT07199517Not applicable1 country
- Pilot Study of an Adapted Partner Navigation Intervention Booster Session for Sustained Healthcare Engagement Among People Who Inject DrugsNot yet recruitingNCT07631559Not applicable1 country
- Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine TherapyRecruitingNCT06948058Not applicable1 country
- Overdose Recovery and Care Access (ORCA) Qualitative Stakeholder Interviews and County-level DataRecruitingNCT06768814Not applicable1 country
- Combining Social Network Strategies and Routine Substance Use ScreeningNot yet recruitingNCT07414459Not applicable1 country
- Evaluation of Clinical Decision Support in Opioid TaperingNot yet recruitingNCT06527079
- Trial of a Harm Reduction Strategy for People With HIV Who Smoke CigarettesRecruitingNCT05642715Not applicable1 country
- Integrating Sexual Pleasure Into Harm Reduction Services for Men Who Have Sex With Men and Transgender Persons Who Engage in Chemsex or Substance Use in ThailandRecruitingNCT07509853Not applicable1 country
- The Implementation of a Trans-tailored Harm Reduction Service for Transgender Persons in Relation to chemsEX and Substance Use (iT-REX)RecruitingNCT07512856Not applicable1 country
- Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation StudyRecruitingNCT075128691 country
- Pre-implementation Study to Develop Trans-tailored Services for Transgender Persons in Relation to chemsEXRecruitingNCT075058751 country
- Smoking Harm Reduction Using E-cigarettes and CytisineNot yet recruitingNCT07274475Not applicable
- Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in TanzaniaNot yet recruitingNCT07475988Not applicable
- Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Overdose PreventionRecruitingNCT06852170Not applicable1 country
- Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette SmokersRecruitingNCT06372899Not applicable1 country
- Harm Reduction for Smokers With Mental IllnessRecruitingNCT06543407Not applicable1 country
- Testing the Effects of Cann'App, a Digital Intervention for Cannabis Harm ReductionEnrolling by invitationNCT07157540Not applicable1 country
- An Augmented Reality Videogame for Alcohol Use Prevention and Harm Reduction in TeensEnrolling by invitationNCT04351958Not applicable1 country
- A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School StudentsRecruitingNCT06115746Not applicable1 country
- E-cigarettes for Harm Reduction Among Smokers With Serious Mental IllnessRecruitingNCT05815199Not applicable1 country
- Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income CountriesRecruitingNCT063951293 countries
- Trial of a Culturally Informed Brief Intervention to Reduce Alcohol Related Health Disparities and Treatment Inequities Among LatinxsRecruitingNCT05800899Not applicable1 country
- Electronic Harm Reduction Treatment for AlcoholRecruitingNCT06702007Phase 31 country
- Innovating Technology Solutions for Residents in Support Housing Communities w SUD Through Community-Engaged ResearchCompletedNCT07001020Not applicable1 country
- Harm Reduction in HIV Primary Care for PLWH Who Use DrugsActive, not recruitingNCT054047501 country
- THRIVE: Culturally AdapTed Harm Reduction InterventionCompletedNCT06609278Not applicable1 country
- Vending Machine Naloxone Distribution for Your Community (VENDY)Active, not recruitingNCT06429436Phase 41 country
- Harm Reduction Strategies for Gay, Bisexual and Other Men Who Have Sex With Men Engaging in ChemsexCompletedNCT06187415Not applicable1 country
- Evaluating an Intervention to Prevent Overdoses in Rural and Urban CountiesActive, not recruitingNCT05463341Not applicable1 country
- Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement StudyCompletedNCT05977881Not applicable1 country
- Clinical Decision Support to Improve System Naloxone Co-prescribingActive, not recruitingNCT062716681 country
- Evaluation of an Educational Intervention on Abscesses in People Who Self-inject DrugsWithdrawnNCT06131788Not applicable1 country
- Counseling for Harm Reduction and Retention in Medication-assisted Treatment - Cherokee NationActive, not recruitingNCT05733442Not applicable1 country
- Preventing Overdose Using Information and Data From the EnvironmentCompletedNCT05096429Not applicable1 country
- Pharmacist-Led Interventions to Increase Access to Medications for Opioid Use Disorders (PLI-MOUD)CompletedNCT05776823Not applicable1 country
- Game-Based Intervention to Reduce Alcohol-Related Harms Among Sexual and Gender Minority YouthTerminatedNCT06215664Not applicable1 country
- Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine RespondersCompletedNCT06554873Phase 31 country
- Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit StimulantsCompletedNCT05493475Not applicable1 country
- Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserineCompletedNCT05994703Phase 21 country
- TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery StudyActive, not recruitingNCT06074341Not applicable1 country
- Therapeutic Education for Harm Reduction in People With Alcohol Use DisorderCompletedNCT039540541 country