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Harm Reduction clinical trials

The registry lists 115 studies for Harm Reduction across more than 10 countries. 39 are recruiting or about to start. 21 of them are mainly about Harm Reduction (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
57
Recruiting
28
Not yet recruiting
9
Terminated
7
Active, not recruiting
7
Status unknown
4

Phase

Phase 2
8
Phase 3
5
Phase 1
4
Phase 4
2

Where

United States
77
Canada
6
Sweden
5
France
4
Thailand
4
Switzerland
3

Who runs them

Rose Research Center, LLC (6) · University of Colorado, Denver (5) · Brown University (5) · Yale University (4) · Institute of HIV Research and Innovation Foundation, Thailand (4) · University of Washington (4) · NYU Langone Health (3) · University of Nebraska (3)

What is being tested here

Drugs under test in Harm Reduction studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Cytisine101
Nicotine023
Nicotine Patch022
Cycloserine001
Naltrexone001
Varenicline011
Nicotine Inhaler001

Coming up

1phase 3 study under way
22studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 28 Harm Reduction studies recruiting now, 24 (86%) set no upper age limit and 2 (7%) stop at 75 or younger. 3 (11%) take children under 18. 0 (0%) are for women only and 2 (7%) for men only; 12 (43%) take healthy volunteers.

Recruiting studies that take each age, of 28
AgeWomenMen
101 (4%)1 (4%)
1817 (61%)19 (68%)
3024 (86%)26 (93%)
4025 (89%)27 (96%)
5025 (89%)27 (96%)
6524 (86%)26 (93%)
7524 (86%)26 (93%)
8523 (82%)25 (89%)

Across all 115 studies, recruiting or not: 26% stop at 75 or younger and 23% at 65; 15% take children; 0% are for women only and 7% for men only; 50% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Harm Reduction studies take

Of 57 interventional studies with no phase under Harm Reduction, half reached primary completion within 28 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase28 mo15–43 · 57 studies—30 mo15–43 · 54 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 115. Browse all 115 → or search them.