An interventional study of SWITCH IT and E-cig Provision Only in Tobacco Dependence, sponsored by Dartmouth-Hitchcock Medical Center. Recruiting at 2 sites in United States. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2026-01-15.
Sponsored by Dartmouth-Hitchcock Medical Center · Not applicable, Interventional, and Treatment
To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation treatment, and to examine self-regulation (using e-cigs instead of cigarettes to cope with stress/distress and self-efficacy) as a potential mechanism for behavior change from SWITCH IT
1,027 studies on the registry are indexed under Tobacco Use Disorder; 128 are open to participants now.
This study's planned enrollment of 250 is above the median of 90 across 892 interventional studies indexed under Tobacco Use Disorder.
Browse Tobacco Use Disorder studies →Dartmouth-Hitchcock Medical Center is the lead sponsor of 488 studies on the registry; 71 are open to participants now.
Of its 31 completed or terminated interventional studies of FDA-regulated products, 21 (68%) have results posted.
Counted across the registry records on this site, refreshed daily.
Diagnostic Criteria (must have one to be eligible):
Additional Inclusion Criteria:
Exclusion Criteria:
Participants randomized to this condition will receive a supply of NJOY Daily e-cigarettes for the first 8 weeks of the study.
Other: E-cig Provision Only
Participants randomized to this condition will receive a supply of e-cigarettes and behavioral support and coaching, protocolized intervention, SWITCH IT, for the first 8 weeks of the study.
Behavioral: SWITCH IT
Behavioral support for switching, 7-10 sessions with SWITCH IT coach delivered during the first 8 weeks of the study. SWITCH IT participants will also have the opportunity to receive supported "field trips" to explore e-cigarette options based on availability, cost, and preferences during week 4 and week 6.
Provision of e-cigarettes (NJOY) based on combusible use for the first 8 weeks of the study.
Change in Urine NNAL
urine levels of NNAL
Time frame: baseline to 8 weeks, 8 weeks to 26 weeeks
Change in CO level
carbon monixide level less than 6
Time frame: baseline to 8 weeks, 8 weeks to 26 weeks
Change in self-reported cigarette use
self-report of combustible cigarette use
Time frame: baseline to 8 weeks 8 weeks to 16 weeks
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Dartmouth-Hitchcock Medical Center →