Halitosis clinical trials
The registry lists 93 studies for Halitosis across more than 10 countries. 17 are recruiting or about to start. 67 of them are mainly about Halitosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-28.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
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· Enrollment: 300 → 450 participants
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Status
Who runs them
University of Nove de Julho (14) · Hadassah Medical Organization (4) · Universitaire Ziekenhuizen KU Leuven (3) · Tokyo Medical and Dental University (3) · University of Athens (3) · Mebo Research, Inc. (3) · Riyadh Colleges of Dentistry and Pharmacy (2) · University Hospital, Strasbourg, France (2)
What is being tested here
Drugs under test in Halitosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026Effects of a 50+ Toothpaste on Halitosis and Oral Comfort in Healthy Adults · University of Pavia
- Dec 2026Effects of Green Tea Mouthwash on Halitosis, Periodontal Health, and Stress in Orthodontic Patients · Universiti Sains Malaysia
- Dec 2026Innovative Mouthwash in School-Aged Children With Fixed Orthodontic Appliances · Plovdiv Medical University
- Jan 2027Evaluation of the Safety and Efficacy of SALI-10 Probiotic Lozenges · Ostia Sciences
- Jan 2027Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus · University of Sao Paulo
- Jun 2027Tedlar Bag Stability of Volatile Sulfur Compounds for Remote Halitosis Diagnosis · University Hospital, Strasbourg, France
Who these studies take
Of the 9 Halitosis studies recruiting now, 2 (22%) set no upper age limit and 6 (67%) stop at 75 or younger. 1 (11%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (56%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (11%) | 1 (11%) |
| 18 | 8 (89%) | 8 (89%) |
| 30 | 7 (78%) | 7 (78%) |
| 40 | 6 (67%) | 6 (67%) |
| 50 | 6 (67%) | 6 (67%) |
| 65 | 5 (56%) | 5 (56%) |
| 75 | 3 (33%) | 3 (33%) |
| 85 | 3 (33%) | 3 (33%) |
Across all 93 studies, recruiting or not: 66% stop at 75 or younger and 54% at 65; 22% take children; 1% are for women only and 5% for men only; 67% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Halitosis studies take
Of 43 interventional studies with no phase under Halitosis, half reached primary completion within 10 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 10 mo3–18 · 43 studies | — | 10 mo3–18 · 35 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 93. Browse all 93 → or search them.
- Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT017931681 country
- Effectiveness of Aquamin® in Mitigating HalitosisRecruitingNCT05058638Phase 21 country
- Effects of a 50+ Toothpaste on Halitosis and Oral Comfort in Healthy AdultsNot yet recruitingNCT07780474Not applicable1 country
- Evaluation of the Safety and Efficacy of SALI-10 Probiotic LozengesRecruitingNCT07508839Not applicable1 country
- Effect of Dental Education Duration on Halitosis and Associated FactorsNot yet recruitingNCT077408761 country
- Innovative Mouthwash in School-Aged Children With Fixed Orthodontic AppliancesNot yet recruitingNCT07710144Not applicable1 country
- Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic PatientsRecruitingNCT07693972Not applicable1 country
- Tedlar Bag Stability of Volatile Sulfur Compounds for Remote Halitosis DiagnosisNot yet recruitingNCT07602309Not applicable1 country
- Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes MellitusRecruitingNCT07463859Not applicable1 country
- The Additional Effect of Tongue Scraping on Halitosis Parameters in Initial Periodontal TherapyRecruitingNCT06091228Not applicable1 country
- Oral Probiotics for Halitosis in Healthy AdultsNot yet recruitingNCT07384130Not applicable1 country
- Halitosis, Sleep and Mental Health in Bariatric Surgery CandidatesNot yet recruitingNCT07175142
- Investigating the Effect of Chlorine Dioxide and Chlorhexidine Mouthwash on Bad BreathEnrolling by invitationNCT06219226Not applicable1 country
- Role of Kefir Mouth Wash in Oral Health Status AmeliorationRecruitingNCT06900881Phase 2/31 country
- Comparative Study Between Photodynamic Therapy with LED Associated with Probiotics in the Treatment of HalitosisRecruitingNCT06583720Phase 11 country
- Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.RecruitingNCT06882564Phase 31 country
- Chios Mastic Toothpaste and Halitosis and Oral Hygiene in Orthodontic PatientsNot yet recruitingNCT06766097Not applicable1 country
- Olfactory Function and Oral Malodor in Periodontitis Before and After Periodontal TherapyCompletedNCT07424300Not applicable1 country
- Effects of Green Tea Mouthwash on Halitosis, Periodontal Health, and Stress in Orthodontic PatientsActive, not recruitingNCT07829224Not applicable1 country
- Evaluation of the Stability of Sulfur Volatile Compounds From Exhaled Air for Halitosis DiagnosisCompletedNCT06483646Not applicable1 country
- A Clinical Trial to Evaluate the Effects of Super Liver Liquid Drops on Gut Health, Digestive Comfort, and Daily Energy LevelsActive, not recruitingNCT07742657Not applicable1 country
- Evaluation of Periodontal Treatment in Patients With BronchiectasisCompletedNCT02514226Not applicable1 country
- A Clinical Trial to Evaluate the Effects of Larineco Remineralizing Gum on Oral Health, Breath Freshness, Tooth Sensitivity, and Gum ComfortActive, not recruitingNCT07692581Not applicable1 country
- Oral and Dental Health Status in Patients Suffering From Chronic Kidney DiseaseCompletedNCT02114281Not applicable1 country
- Oral Probiotics and Denture Care in Saudi Arabia: Evaluating Knowledge, Practices, and the Future of Innovative Hygiene SolutionsCompletedNCT074751951 country
- Effect of Whitening Agent With Emulsion Gel in Saliva and HalitosisActive, not recruitingNCT06194123Not applicable1 country
- Antimicrobial Photodynamic Therapy Or Lingual Scraper Associated With Periodontal Treatment In The Reduction Of Halitosis.CompletedNCT07433816Not applicable1 country
- Evaluation of a Stannous Fluoride Dentifrice for Control of Oral MalodorCompletedNCT07425509Not applicable1 country
- Coblation and Traditional Adenoidectomy: A Comparative StudyCompletedNCT07417007Not applicable1 country
- Effect of Toothpastes on Oral MalodorCompletedNCT07329062Not applicable1 country
- Effect of a Mouthwash Containing Chlorhexidine and Chlorine Dioxide on HalitosisCompletedNCT07265102Not applicable1 country
- Adjunctive Effect of Photodynamic Therapy on HalitosisCompletedNCT06764342Not applicable1 country
- Cotinus Coggygria Mouthwash and Halitosis and Oral Hygiene in Orthodontic PatientsCompletedNCT07254819Not applicable1 country
- The Effect of Oral Probiotics on Oral Hygiene and Halitosis in Orthodontic Patients.CompletedNCT05651503Not applicable1 country
- Impact of Visual Stimuli on Pediatric Oral Hygiene PerformanceCompletedNCT07150429Not applicable1 country
- Effects of Mechanical, Chemical, and Combination Methods on HalitosisCompletedNCT06890104Not applicable1 country
- Chios Mastic Mouthwash and Halitosis and Oral Hygiene in Orthodontic PatientsCompletedNCT05647369Not applicable1 country
- A Clinical Study to Examine the Effects of an Experimental Toothpaste Compared to a Regular Fluoride Toothpaste on Breath Odor in a Population With GingivitisCompletedNCT05524948Not applicable1 country
- Assessment of Photodynamic Therapy With Annatto and Led for the Treatment of Halitosis in Mouth-Breathing ChildrenCompletedNCT05590897Phase 1/21 country
- Effect of Wearing Face Masks on Salivary Parameters and HalitosisCompletedNCT04914208Not applicable1 country
- Questionnaire Regarding the Effect of Wearing Face Masks on Oral HealthCompletedNCT04632004Not applicable1 country
- Comparative Study Between Photodynamic Therapy With Urucum and LED and Probiotics in Halitosis ReductionCompletedNCT03996044Phase 11 country
- Effects of Curcumin-containing Toothpaste on Dental Biofilm and Associated Oral HalitosisCompletedNCT04998617Not applicable1 country
- Evaluation of Halitosis After Treatment With Photodynamic Therapy Associated With Periodontal TreatmentCompletedNCT03996915Not applicable1 country
- Evaluation of the Treatment of Halitosis With Photodynamic Therapy in Older Patients With Complete DentureCompletedNCT03960983Not applicable1 country
- Evaluation of Halitosis After Treatment With Photodynamic TherapyCompletedNCT03973684Not applicable1 country
- Treatment of Halitosis With Photodynamic Therapy in Older PatientsCompletedNCT03591484Not applicable1 country
- Oral and Gut Microbiota Changes During Long-term Fasting in HumansCompletedNCT05449249Not applicable1 country
- Evaluation of Clinical and Cost-effectiveness of Different Mouthwashes on Controlling Halitosis Among a Group of Egyptian ChildrenStatus unknownNCT04905940Not applicable
- Effect of an Investigational Lozenge (Biofresh® 4plus) Versus Placebo Control on Oral Malodor (Intra-Oral Halitosis)CompletedNCT05413382Not applicable1 country