An observational study in Denture Stomatitis, Dentures and Halitosis, sponsored by King Saud University. Completed at 1 site in Saudi Arabia. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-16.
Sponsored by King Saud University · Observational
The goal of this observational study is to learn about denture wearers' knowledge, awareness, and self-reported practices regarding denture hygiene and oral probiotics, and to assess whether these are associated with clinical oral findings and microbial colonization in adult denture wearers (18 years and older), including complete and partial denture users treated at King Saud University Dental Clinics within the past five years. The main questions it aims to answer are:
What are the levels of knowledge, awareness, and practices related to denture hygiene and oral probiotics among adult denture wearers?
What is the prevalence of denture-related oral conditions and bacterial/fungal colonization, and how are these related to denture hygiene knowledge and self-reported hygiene practices?
Participants will:
Complete an electronic questionnaire in Arabic or English about demographics, denture hygiene knowledge, awareness of oral probiotics, and current denture care practices.
Attend a 15-20 minute clinical visit for examination of dentures and oral mucosa.
Be asked to avoid cleaning their denture for at least 12 hours before the visit.
Undergo plaque sample collection from dentures and oral tissues; partially edentulous participants will also have additional samples collected from abutment areas.
Have samples analyzed using real-time PCR and culture methods (CFU) to detect bacterial and fungal microorganisms.
21 studies on the registry are indexed under Stomatitis, Denture; 1 is open to participants now.
Browse Stomatitis, Denture studies →King Saud University is the lead sponsor of 169 studies on the registry; 21 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult men and women aged 18 years or older who are currently wearing at least one removable denture (complete or partial) and who received denture treatment at King Saud University Dental Clinics/Dental University Hospital within the past five years. Participants are recruited by convenience sampling from eligible patients identified through the SALUD electronic dental records system.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Adults 18 years or older
Currently wearing at least one removable denture (complete or partial)
Denture received/used within the past five years
Willing and able to provide
Exclusion Criteria:
Severe systemic conditions affecting oral health, such as:
Uncontrolled diabetes ( > 7) and
Pregnancy
Breastfeeding
Cognitive or physical impairment that limits the ability to perform routine oral and denture care practices
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A blood test of average blood sugar over the past two to three months, given as a percentage or in mmol/mol. 6.5% (48 mmol/mol) or more is the usual threshold for diabetes, normally confirmed by a second test.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
HbA1c
A blood test of average blood sugar over the past two to three months, given as a percentage or in mmol/mol. 6.5% (48 mmol/mol) or more is the usual threshold for diabetes, normally confirmed by a second test.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients with removable partial dentures
Other: This is a cross-sectional observational study. Participants are not assigned to any treatment or preventive intervention.
Patients with complete denture
Other: This is a cross-sectional observational study. Participants are not assigned to any treatment or preventive intervention.
This is a cross-sectional observational study. Participants are not assigned to any treatment or preventive intervention. They will only undergo questionnaire completion, clinical examination, and noninvasive plaque and mucosal sample collection.
Knowledge, awareness, and self-reported hygiene practices related to denture hygiene and oral probiotics among adult denture wearers, assessed using a validated questionnaire
Knowledge, awareness, and self-reported hygiene practices related to denture hygiene and oral probiotics among adult denture wearers, assessed using a validated questionnaire
Time frame: Baseline
Prevalence of denture-related oral complications and bacterial/fungal colonization, assessed through clinical examination, culture (CFU), and real-time PCR
Prevalence of denture-related oral complications and bacterial/fungal colonization, assessed through clinical examination, culture (CFU), and real-time PCR
Time frame: Baseline
Plan to share: No
No publications or documents are linked to this record.
Ran from Sep 2025 to primary completion in Mar 2026, 6 months.
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This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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