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Frailty clinical trials

The registry lists 1,284 studies for Frailty across more than 10 countries. 452 are recruiting or about to start. 776 of them are mainly about Frailty (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

ClinicalTrials.gov finds 1,586 studies for Frailty. How that becomes 1,284 here

This page counts the studies the registry files under Frailty, and those it files under no condition that list Frailtythemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,586Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −25List Frailty as a condition, but the registry did not file them under itMost often written as “Frailty at Older Adults” (7), “Cognitive Frailty” (4), and “Oral Frailty” (3). The registry filed them under other conditions only, most often Sarcopenia (5) and Motor Activity (4).
  3. −277Match it another way258 name it in the title and 19 in a keyword.
  4. 1,284The count on this page36 of them list Frailty in their own words; the registry filed them under no condition.

Get an email when these change. Save the Frailty studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Completed
567
Recruiting
300
Status unknown
147
Not yet recruiting
128
Active, not recruiting
67
Terminated
27

Phase

Phase 2
52
Phase 1
27
Phase 3
15
Phase 4
14
Early Phase 1
8

Where

United States
185
Spain
132
Canada
83
Turkey
82
Taiwan
68
United Kingdom
64

Who runs them

The Hong Kong Polytechnic University (16) · National Taiwan University Hospital (14) · VA Office of Research and Development (12) · Fundacion Miguel Servet (11) · Jewish General Hospital (11) · The University of Hong Kong (10) · National Yang Ming Chiao Tung University (9) · University Hospital, Toulouse (9)

What is being tested here

Drugs under test in Frailty studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Fisetin204
Testosterone127
Nicotinamide-beta-riboside103
Creatine monohydrate102
Creatine102
Beta-hydroxyisovaleric acid102
Solizmestrocel102
Protein Supplement102
Coenzyme Q10112
Vitamin D102

Drug classes tested here Androgens 1 open · Tyrosine kinase inhibitors (TKIs) 3

Coming up

3phase 3 studies under way
141studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 300 Frailty studies recruiting now, 236 (79%) set no upper age limit and 9 (3%) stop at 75 or younger. 7 (2%) take children under 18. 10 (3%) are for women only and 2 (1%) for men only; 66 (22%) take healthy volunteers.

Recruiting studies that take each age, of 300
AgeWomenMen
107 (2%)7 (2%)
1892 (31%)89 (30%)
3099 (33%)96 (32%)
40104 (35%)101 (34%)
50121 (40%)116 (39%)
65254 (85%)247 (82%)
75291 (97%)283 (94%)
85278 (93%)271 (90%)

Across all 1,284 studies, recruiting or not: 3% stop at 75 or younger and 1% at 65; 3% take children; 2% are for women only and 1% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Frailty studies take

Of 20 phase 2 interventional studies under Frailty, half reached primary completion within 39 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 239 mo28–94 · 20 studies——
Interventional, no phase22 mo10–39 · 517 studies—22 mo11–39 · 513 studies
Observational29 mo12–55 · 292 studies—29 mo12–55 · 289 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting6

Show 1 more

Results posted1

Newly registered18

Show 13 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,284. Browse all 1,284 → or search them.