Frailty clinical trials
The registry lists 1,190 studies for Frailty across more than 10 countries. 425 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.
Status
- Completed
- 508
- Recruiting
- 277
- Status unknown
- 141
- Not yet recruiting
- 126
- Active, not recruiting
- 67
- Terminated
- 25
Phase
- Phase 2
- 50
- Phase 1
- 22
- Phase 3
- 15
- Phase 4
- 13
- Early Phase 1
- 7
Where
- United States
- 178
- Spain
- 113
- Canada
- 68
- United Kingdom
- 65
- Taiwan
- 64
- China
- 63
Who runs them
The Hong Kong Polytechnic University (12) · National Taiwan University Hospital (12) · VA Office of Research and Development (11) · Fundacion Miguel Servet (11) · Jewish General Hospital (9) · Mayo Clinic (9) · National Yang Ming Chiao Tung University (8) · The University of Hong Kong (8)
Studies
Recruiting first, then most recently updated. Showing 50 of 1,190 — search for more.
- Human Albumin Combined With Plasma Exchange for Frailty InterventionNot yet recruitingNCT07836127Not applicable1 country
- Frailty and Outcomes in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Nationwide Swedish Cohort StudyNot yet recruitingNCT07837219
- Integrating Geriatric 8 (G8) Screening and Cancer and Age Research Group (CARG) Toxicity Assessment Score Into Routine Care for Older Adults With CancerNot yet recruitingNCT07837505
- A Pilot Study to Explore the Feasibility of Navigator and Coach Support for Community Participation by Older PeopleNot yet recruitingNCT07836465Not applicable1 country
- Immune Aging and Advanced Therapy Outcomes in Older Adults With IBDNot yet recruitingNCT07828886
- VIVI-OLIVE: Multicomponent Exercise and Extra Virgin Olive Oil in Older Adults at High Risk of FallsRecruitingNCT07829484Not applicable1 country
- Involvement of Muscle Mitochondrial Dysfunction in Frailty in Older Adults. Role of ExerciseRecruitingNCT07828847Not applicable1 country
- Targeting HealthY Eating to Maintain Energy While Living With CancerNot yet recruitingNCT07826871Phase 21 country
- A Frailty-specific Prehabilitation Program for Mild to Moderately Frail Patients Undergoing Cardiac Surgeries/ProceduresRecruitingNCT07824700Not applicable1 country
- Fall Prevention PathwaysRecruitingNCT07824141Not applicable1 country
- Frailty in Outpatient Digestive EndoscopyRecruitingNCT065075271 country
- The VIP3 (Very Old Intensive Care Patients) Study: Family Involvement in Treatment Decisions for Old ICU PatientsRecruitingNCT070359511 country
- Preoperative Frailty and Postoperative Outcomes in Older Patients Undergoing Surgery for Gastrointestinal CancerRecruitingNCT078153921 country
- Multi-Component Nutrition, Intrinsic Capacity, and Physical Function in Older AdultsNot yet recruitingNCT07815158Not applicable1 country
- Impact of a Physical Exercise Program in a Rural AreaRecruitingNCT06842849Not applicable1 country
- Perioperative Prehabilitation on Markers of Fitness and Frailty in Patients Undergoing Elective SurgeryNot yet recruitingNCT05977556Not applicable1 country
- URINARY INCONTINENCE AND GERIATRIC SYNDROMESRecruitingNCT078137021 country
- Preventing Falls in Older Adults With Cognitive FrailtyRecruitingNCT06854731Not applicable1 country
- Longevity Metrics AI/ML Development StudyRecruitingNCT078086191 country
- Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.RecruitingNCT06374537Not applicable1 country
- Human Observatory StudyRecruitingNCT076467821 country
- 100-Year Human Aging StudyRecruitingNCT075637771 country
- Health Ahead Comparative Effectiveness StudyRecruitingNCT07669168Not applicable1 country
- The Effect of Volunteer-Engaged Lifestyle Optimisation Via ICOPE on Sarcopenia in Older Adults (VELO-S)RecruitingNCT07345832Not applicable1 country
- Vivifrail Exercise Program in Nonagenarians: Effects on Function, Muscle, and CognitionEnrolling by invitationNCT07731529Not applicable1 country
- Baltimore Longitudinal Study of AgingRecruitingNCT002332721 country
- BIOANCIENT_EX: Effects of a Physical Exercise Program in Centenarians of the BIOANCIENT Cohort: A Randomized Clinical Trial.Enrolling by invitationNCT07723339Not applicable1 country
- Older Adults' Recovery Dynamics After Cardiac SurgeryNot yet recruitingNCT077937081 country
- Investigating the Combined Effects of Protein, Blueberries, and Exercise on Cardiovascular Health and Frailty in Older Nova ScotiansRecruitingNCT06693271Not applicable1 country
- Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and OlderRecruitingNCT05858034Not applicable1 country
- Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older AdultsNot yet recruitingNCT07573995Not applicable1 country
- MItochondrial Intervention for Resilience in Older Adults With Coenzyme Q10Not yet recruitingNCT07772336Not applicable
- The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older AdultsRecruitingNCT06027554Phase 21 country
- Cognitive Impact Associated With Surgery For Gastric Or Esophageal CancerRecruitingNCT066872911 country
- Multicomponent Exercise and Comprehensive Geriatric Assessment Program (FRAIL+AP) for Frail Older Adults in Primary CareRecruitingNCT07643064Not applicable1 country
- Acupoint Stimulation and Exercise for Taiwanese Pre-frail Older AdultsRecruitingNCT07732530Not applicable1 country
- Funcional Recovery After Minithoracotomy or Sternotomy for CABG in Frail PatientsNot yet recruitingNCT07742475Not applicable
- Interprofessional Education Programme for Nursing and Physiotherapy Students Providing Home-Based Care to Older AdultsRecruitingNCT07184333Not applicable1 country
- EASIX Score and Post-Induction Hypotension in Frail Patients Undergoing Non-Cardiac SurgeryRecruitingNCT076427651 country
- Niaoduqing Granules in Older Adults With Impaired Kidney FunctionRecruitingNCT07741292Phase 41 country
- Development of a Frailty Risk Prediction Model and Preliminary Evaluation of a Risk-stratified Social Robot-assisted Intervention in Middle-aged and Older Spousal CaregiversNot yet recruitingNCT07740031Not applicable
- In-Person, Online, and Hybrid Healthy-Aging Education for Pre-Frailty and Frailty in Older AdultsNot yet recruitingNCT07738393Not applicable1 country
- Effects of a Community-based Multicomponent Physical Exercise Program on Physical Function, Frailty, and Sarcopenia in Older Adults From the Municipality of Santoña: a Quasi-experimental Study.Not yet recruitingNCT07732478Not applicable1 country
- Ready for Safe Cancer Treatment (RESET): A Comprehensive Perioperative Program for Surgical OncologyRecruitingNCT07727876Not applicable1 country
- Frailty Syndrome and Its Associated Factors Among Elderly PatientsNot yet recruitingNCT07727811
- Nurse-Led Telehealth Frailty Management in Older AdultsRecruitingNCT07634406Not applicable1 country
- STRIDE: Strength of The Calf Muscles and Their Role In Declining Effectiveness of Movement With AgingNot yet recruitingNCT077264981 country
- Comparison of Preoperative Frailty Assessment ToolsRecruitingNCT068895451 country
- The Effect of Teleconsultation, on the Reversibility of Frailty in Geriatric Patients Post HospitalizationNot yet recruitingNCT07712276Not applicable1 country
- Analgesia Methods and Early Mobilization in Geriatric ICU Patients After Major SurgeryRecruitingNCT077099751 country