Drug
Butylphthalide clinical trials
Also written DL-3-n-butylphthalide.
- studies test it
- 22
- open now
- 12
- in phase 3
- 8
- first study started
- 2010
Keep track of what changes. Save the butylphthalide studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Other names
Combined with it in one product
Studies by the year they started
22 studies that test it; most in 2024 (4)
| Year | Studies |
|---|---|
| 2010 | 1 |
| 2011 | 1 |
| 2015 | 1 |
| 2017 | 1 |
| 2018 | 3 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 2 |
| 2023 | 1 |
| 2024 | 4 |
| 2025 | 3 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 1
- Phase 2
- 4
- Phase 3
- 8
- Phase 4
- 9
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 20
Beijing Tiantan Hospital (2) · Tang Ziren (2) · Yi Yang (1) · CSPC-NBP Pharmaceutical Co., Ltd. (1) · Shanghai 6th People's Hospital (1) · Second Affiliated Hospital, School of Medicine, Zhejiang University (1) · Jinling Hospital, China (1) · Nanfang Hospital, Southern Medical University (1)
Often tested with
Tested in the same studies.
Sodium Chloride (2) · Cerebrolysin (1) · Isosorbide mononitrate (1)
Studies
Open first, then newest update. How each study uses butylphthalide is read from its arms, and is right about nine times in ten.
Testing it · 22
- Efficacy and Safety of Butylphthalide in the Treatment of Multiple System AtrophyRecruitingPhase 2/3Second Affiliated Hospital, Zhejiang University, School of MedicineNCT07518810Written as 3-N-butylphthalide
- Butylphthalide for Brain Edema After Endovascular TreatmentNot yet recruitingPhase 4Nanfang Hospital, Southern Medical UniversityNCT07528456Written as Butylphthalide
- Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)Not yet recruitingPhase 3Beijing Tiantan HospitalNCT07252544Written as Butylphthalide
- Butylphthalide for Long-term Efficacy in Minor Stroke StudyNot yet recruitingPhase 3Peking Union Medical College HospitalNCT07230587Written as Butylphthalide
- Butylphthalide for Cognitive Impairment in Elderly Patients With Focal EpilepsyRecruitingPhase 4First Affiliated Hospital of Wenzhou Medical UniversityNCT07193277Written as Butylphthalide
- Neuroprotective Effect of Butylphthalide for Cardiac Arrest PatientsRecruitingPhase 4Tang ZirenNCT06572085Written as Butylphthalide and Sodium Chloride Injection
- Butylphthalide's Safety and Efficacy for Improving Neurological Function Prognosis in Patients With Cardiac Arrest (BNCA Trial)RecruitingPhase 4Tang ZirenNCT06353334Written as Butylphthalide and Sodium Chloride Injection
- A Randomized Controlled Trial on the Efficacy and Safety of Butylphthalide in Reducing Myocardial Infarction Size and Improving Outcomes in STEMI Patients After Primary PCINot yet recruitingPhase 3Xiangya Hospital of Central South UniversityNCT06704685Written as Butylphthalide
- Effects of DL-3-n-butylphthalide on Chemotherapy-Induced Cognitive ImpairmentNot yet recruitingPhase 4First Hospital of China Medical UniversityNCT06508671Written as DL-3-n-butylphthalide
- Effect of Butyphthalide on Cognitive Level Change After Cerebral Vascular Event-a Randomized Control Trial (Be-CLEVER)RecruitingPhase 3Fudan UniversityNCT05976152Written as dl-3-butylphthalide
- For Patients With Ischemic Stroke, Clinically Study the Effectiveness and Safety of Butylphthalide.RecruitingPhase 4Qianfoshan HospitalNCT05068349Written as Butylphthalide
- Efficacy of Butylphthalide on Symptomatic Atherosclerotic Stenosis in Middle Cerebral ArteryNot yet recruitingNot applicableFirst Affiliated Hospital, Sun Yat-Sen UniversityNCT06331494Written as Butylphthalide
- NBP in Women With Metastatic Breast Cancer to Prevent Nab-paclitaxel Induced Toxic NeuropathyWithdrawnPhase 2Conjupro Biotherapeutics, Inc.NCT04675450Written as NBP Softgel Capsules
- Efficacy and Safety of Butylphthalide for Acute Ischemic Stroke Patients Receiving Intravenous Thrombolysis or Endovascular TreatmentCompletedPhase 3Beijing Tiantan HospitalNCT03539445Written as Butylphthalide
- Effectiveness of Butylphthalide on Dynamic Cerebral Autoregulation in Patients With Acute Ischemic Stroke.CompletedPhase 4Yi YangNCT03413202Written as butylphthalide(NBP)
- NBP in Adult Patients With Acute Ischemic Stroke (AIS)CompletedPhase 2CSPC-NBP Pharmaceutical Co., Ltd.NCT02905565Written as NBP Softgel Capsules
- Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic StrokeCompletedPhase 1/2Shanghai 6th People's HospitalNCT02149875Written as Dl-3-n-butylphthalide
- The Impact of NBP on the Collateral Circulation in ICA/M1 OcclusionCompletedPhase 4Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT02594995Written as NBP
- NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular EventsStatus unknownPhase 3yuanli ZhaoNCT04205578Written as dl-3-n-butylphthalide (NBP)
- Study of Collateral Circulation in Patients With Symptomatic Intracranial Anterior Circulation OcclusionStatus unknownPhase 4The Second Hospital of Hebei Medical UniversityNCT04091412Written as Butylphthalide Soft Capsules
Codes
What other systems call butylphthalide · ClinicalTrials.gg INT002847
- MeSH (NLM) C0271253-n-butylphthalideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 822Q956KGMBUTYLPHTHALIDEConfirmed FDA, NLM, Wikidata
- RxNorm 1484499Confirmed FDA, Wikidata
- Wikidata Q5003180butylphthalideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C171720ButylphthalideOne source FDA
- DrugBank DB12749One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C027125 | 3-n-butylphthalide | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 822Q956KGM | BUTYLPHTHALIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1484499 | — | Confirmed FDA, Wikidata |
| Wikidata | Q5003180 | butylphthalide | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C171720 | Butylphthalide | One source FDA |
| DrugBank | DB12749 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.