An observational study in Myocardial Bridging and Coronary Atherosclerosis, sponsored by Sohag University. Recruiting at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2026-11-04.
Sponsored by Sohag University · Observational
Myocardial bridging is a condition in which a segment of a coronary artery passes through the heart muscle instead of running on its surface. This study aims to determine the prevalence of coronary myocardial bridging and investigate its relationship with coronary atherosclerotic plaques using multidetector computed tomography coronary angiography (MDCT-CA).
The study will include at least 50 patients referred for coronary CT angiography at Sohag University Hospital and New Sohag University Hospital. CT images will be evaluated to identify myocardial bridges, determine their location, measure their length and depth, and assess the presence, location, and characteristics of coronary atherosclerotic plaques.
The findings will be analyzed to investigate the association between myocardial bridging and coronary atherosclerotic plaques.
Myocardial bridging is an anatomical variant characterized by an intramyocardial course of a segment of an epicardial coronary artery. Although it is frequently considered a benign finding, several studies have suggested an association between myocardial bridging and coronary atherosclerotic plaque formation, particularly in the coronary segment proximal to the bridged segment.
This prospective observational study aims to determine the prevalence of coronary myocardial bridging using multidetector computed tomography coronary angiography (MDCT-CA) and investigate its relationship with coronary atherosclerotic plaques.
The study will be conducted at the Diagnostic and Interventional Radiology Departments of Sohag University Hospital and New Sohag University Hospital. At least 50 patients referred for coronary CT angiography will be included, without age or sex restrictions.
Coronary CT angiography examinations will be performed using 128-row or 160-row multidetector CT scanners. The imaging protocol will include coronary calcium scoring and contrast-enhanced coronary CT angiography with electrocardiographic gating.
The coronary arteries, including the right coronary artery, left main coronary artery, left anterior descending artery, and left circumflex artery, will be evaluated for the presence of myocardial bridging and coronary atherosclerotic plaques.
For each detected myocardial bridge, the following parameters will be assessed:
Coronary atherosclerotic plaques will be assessed regarding their presence, location, and characteristics. The findings will subsequently be analyzed to investigate the relationship between myocardial bridging and coronary atherosclerotic plaques.
The collected data will be statistically analyzed to determine the prevalence of myocardial bridging and evaluate its association with coronary atherosclerotic plaques.
5,683 studies on the registry are indexed under Coronary Artery Disease; 960 are open to participants now.
This study's planned enrollment of 50 is below the median of 334 across 1,979 observational studies indexed under Coronary Artery Disease.
Browse Coronary Artery Disease studies →Sohag University is the lead sponsor of 1,225 studies on the registry; 632 are open to participants now.
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The study population will consist of patients referred to the Diagnostic and Interventional Radiology Department at Sohag University Hospital and New Sohag University Hospital to undergo coronary CT angiography. At least 50 patients of both sexes, without age restrictions, will be included in this prospective observational study to assess the prevalence of coronary myocardial bridging and its relationship with coronary atherosclerotic plaques.
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Exclusion Criteria:
Number of participants with Prevalence of Coronary Myocardial Bridging
Determination of the prevalence of coronary myocardial bridging among patients undergoing multidetector computed tomography coronary angiography (MDCT-CA), based on the identification of intramyocardial coronary artery segments.
Time frame: Day 1 (At the time of coronary CT angiography examination"
Plan to share: No — Individual participant data will not be shared with other researchers to maintain patient confidentiality and protect personal information. Study results may be disseminated in scientific publications in aggregate form without identifying individual participants.
Started Oct 2026 (actual). Primary completion is estimated for Jun 2027, 8 months after the start.
Of 728 non-industry observational studies under Coronary Artery Disease, half reached primary completion within 48 months of starting (the median), counting those still running; a quarter within 23 and three quarters within 122. This study's planned 8 months is below that.
Counting every sponsor, half of 860 studies reached it within 42 months; a quarter within 21 and three quarters within 88.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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