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Not yet recruitingNCT07888465Updated Oct 22, 2026

MCG Algorithm Optimization Study in Patients With Coronary Artery Stenosis

An observational study in Coronary Artery Disease, sponsored by AMCG. Not yet recruiting. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2026-10-22.

Sponsored by AMCG · Observational

Updated Oct 22, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
165
Ages
19 Years and older
Sex
All
01

Study summary

This prospective, multicenter study aims to optimize the Magnetocardiography (MCG) algorithm for detecting myocardial ischemia in patients with coronary artery stenosis.

Eligible patients will undergo MCG measurements at rest and following treadmill exercise stress testing. Adenosine pharmacological stress testing may also be performed at the investigator's discretion.

The results of this study will provide clinical data for improving the diagnostic accuracy of MCG in patients with suspected coronary artery disease.

02

Conditions studied

  • Coronary Artery Disease
03

In context

Coronary Artery Disease

5,676 studies on the registry are indexed under Coronary Artery Disease; 958 are open to participants now.

This study's planned enrollment of 165 is below the median of 335 across 1,978 observational studies indexed under Coronary Artery Disease.

Browse Coronary Artery Disease studies →

Lead sponsor

AMCG is the lead sponsor of 2 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients with suspected or confirmed coronary artery disease

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adults with suspected or confirmed coronary artery disease.
  • Patients able to undergo the required study assessments.
  • Patients who voluntarily provide written informed consent.

Exclusion criteria

Exclusion Criteria:

  • Patients with contraindications to the required study procedures.
  • Patients with unstable cardiovascular conditions.
  • Patients with medical conditions or prior procedures that may interfere with study assessments.
  • Pregnant or breastfeeding women.
  • Patients considered unsuitable for participation by the investigator.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
165 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Diagnostic Performance of the MCG-S Algorithm (AUROC)

    The diagnostic performance of the MCG-S algorithm will be assessed using the area under the receiver operating characteristic curve (AUROC) against a reference standard.

    Time frame: Day 1 (In-hospital visit)

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Nov 2026; primary completion for Oct 2027, 11 months later.

Of 131 industry-sponsored observational studies under Coronary Artery Disease, half reached primary completion within 27 months of starting (the median), counting those still running; a quarter within 16 and three quarters within 42. This study's planned 11 months is below that.

Counting every sponsor, half of 857 studies reached it within 43 months; a quarter within 22 and three quarters within 88.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 14, 2026
First posted
Oct 22, 2026
StartEst.
Nov 1, 2026
Primary completionEst.
Oct 29, 2027
CompletionEst.
Oct 29, 2027
Last update
Oct 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 22, 2026
Show all 1 update
  1. Oct 22, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07888465
Lead sponsor
AMCG
Responsible party
Sponsor
First posted
Oct 22, 2026
Start date
Nov 1, 2026 (estimated)
Primary completion
Oct 29, 2027 (estimated)
Completion
Oct 29, 2027 (estimated)
Last update
Oct 22, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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