Common Variable Immunodeficiency clinical trials
The registry lists 55 studies for Common Variable Immunodeficiency across more than 10 countries. 12 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 30
- Recruiting
- 9
- Active, not recruiting
- 5
- Status unknown
- 4
- Terminated
- 3
- Enrolling by invitation
- 2
Phase
- Phase 2
- 16
- Phase 3
- 11
- Phase 4
- 5
- Phase 1
- 4
Where
- United States
- 33
- France
- 7
- United Kingdom
- 6
- Germany
- 4
- Italy
- 3
- Canada
- 3
Who runs them
Bio Products Laboratory (5) · CSL Behring (5) · National Institute of Allergy and Infectious Diseases (NIAID) (4) · National Cancer Institute (NCI) (4) · University of South Florida (2) · Paul Szabolcs (2) · Assistance Publique - Hôpitaux de Paris (1) · University of California, Los Angeles (1)
Studies
Recruiting first, then most recently updated. Showing 50 of 55 — search for more.
- Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ImmunityRecruitingNCT04339777Phase 21 country
- Immunoglobulin for Hypogammaglobulinemia Due to Chimeric Antigen Receptor T Cell TherapyRecruitingNCT069895411 country
- Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation DisordersEnrolling by invitationNCT008952711 country
- Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesRecruitingNCT02579967Phase 21 country
- Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and HypogammaglobulinemiaRecruitingNCT06976476Phase 21 country
- Natural History of BronchiectasisRecruitingNCT009435141 country
- Peripheral Helper T-cells in Common Variable ImmunoDeficiencyRecruitingNCT07255157Not applicable1 country
- Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung DiseaseRecruitingNCT04925375Phase 21 country
- IVIG Boya: Safety, Efficacy, and PharmacokineticsNot yet recruitingNCT06150833Phase 3
- Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)RecruitingNCT07284641Phase 21 country
- Usage of Spirometry in Managing IgG Therapy in CVID With Airway DiseaseRecruitingNCT05193552Phase 41 country
- Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency DiseasesEnrolling by invitationNCT01852370Phase 1/21 country
- Leniolisib for Immune Dysregulation in CVIDCompletedNCT06897358Phase 23 countries
- Senolytics Treatment of Interstitial Lung Disease in Common Variable ImmunodeficiencyActive, not recruitingNCT05593588Phase 21 country
- Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune DeficienciesActive, not recruitingNCT01652092Not applicable1 country
- Prediction of Portal Hypertension in Patients With CVID (CVID-pHT)CompletedNCT061451001 country
- Improving the Diagnosis of Common Variable Immune DeficiencyCompletedNCT033356051 country
- Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationActive, not recruitingNCT03663933Phase 21 country
- Immune Disorder HSCT ProtocolActive, not recruitingNCT01821781Phase 21 country
- Severe PID With Lymphoproliferation and NeutropeniaCompletedNCT03427593Not applicable1 country
- Bronchiectasis Prevalence in Patients With Primary Humoral Immunodefiency in Champagne-Ardenne Region, FranceCompletedNCT06355323Not applicable1 country
- COVID-19 Vaccine Responses in PIDD SubjectsActive, not recruitingNCT053214071 country
- Lymphocyte Immunophenotyping in Common Variable ImmunodeficiencyCompletedNCT011967021 country
- Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell TransplantationCompletedNCT03513328Phase 1/21 country
- Early Detection of Primary Antibody Deficiencies in Primary Care Facilities by an Algorithm Driven Selection of Serologic Testing in Individuals at Risk.CompletedNCT053106041 country
- Study of Efficacy of CDZ173 in Patients With APDS/PASLICompletedNCT02435173Phase 2/39 countries
- Composition and Function of Gut Microbiota in Porto-sinusoidal Vascular Disease Associated With Variable Common ImmunodeficiencyStatus unknownNCT054815541 country
- A Study to Evaluate the Benefit of RUCONEST® in Subjects Who Experience ADRs Related to IVIG InfusionsCompletedNCT03576469Phase 41 country
- Study of Safety, Tolerability, and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated With Common Variable ImmunodeficiencyCompletedNCT02199496Phase 1/21 country
- Treatment of Granulomatous and Lymphocytic Interstitial Lung Disease in Patients With Common Variable ImmunodeficiencyWithdrawnNCT02789397Phase 2
- Breadth of Donor Options for People With Inherited Diseases Requiring Allogeneic Hematopoietic Stem Cell Transplant in the Era of Alternative Donor Transplants Using Post-Transplantation CyclophosphamideCompletedNCT031884191 country
- Immune System and Gut Abnormalities in Patients With Common Variable Immunodeficiency With and Without Gastrointestinal SymptomsCompletedNCT000154311 country
- Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency DiseasesCompletedNCT01884311Phase 31 country
- The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency DiseaseCompletedNCT03211689Not applicable1 country
- GLILD Diagnosed in Children and Young Adults With Common Variable ImmunodeficiencyStatus unknownNCT036485671 country
- Assessment of Immunogenicity of Zostavax® in Patients With Antibody Deficiency 60 Years of Age and OlderTerminatedNCT02960399Not applicable1 country
- A Multi-centre Open Study to Assess the Safety and Efficacy of Subgam®CompletedNCT02247141Phase 31 country
- STA-5326 Meslylate to Treat Gut Inflammation Associated With Common Variable ImmunodeficiencyCompletedNCT00263237Phase 11 country
- Investigation of Immune Disorders and DeficienciesStatus unknownNCT019817851 country
- Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency DiseasesCompletedNCT01963143Phase 33 countries
- Construction of a Health-related Quality of Life (HR-QOL) Questionnaire for Patients With Primary Antibody Deficiency DiseaseCompletedNCT02542228
- Clinical and Virological Efficacy of Pegylated Interferon Alpha in the Treatment of Rhinovirus Infection in Patients With Primary Hypogammaglobulinemia: Randomized Controlled TrialStatus unknownNCT02661477Phase 21 country
- "Prime Boost" Vaccination Strategy Combining Conjugated Anti- Pneumococcal Vaccine (s0) and Polysaccharide Anti- Pneumococcal Vaccine (s4) Compared to Polysaccharide Anti- Pneumococcal Vaccine Alone (s4) In Patients With Common Variable ImmunodeficiencyTerminatedNCT01489618Phase 21 country
- The Rifaximin Study in CVIDCompletedNCT01946906Phase 41 country
- Randomized Study of Polyethylene-Glycol-Conjugated Interleukin 2 in Patients With Common Variable ImmunodeficiencyCompletedNCT00004695Not applicable
- A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary ImmunodeficiencyCompletedNCT01289847Phase 43 countries
- Efficacy and Safety of Vivaglobin® in Previously Untreated Patients With Primary ImmunodeficiencyCompletedNCT00520494Phase 44 countries
- Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases.CompletedNCT00278954Phase 31 country
- Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)CompletedNCT00322556Phase 31 country
- Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)CompletedNCT00168025Phase 3