Common Variable Immunodeficiency: all 54 studies

Page 1 of 1. Open to participants first (13), then studies with results posted, then the rest; newest registration first within each.

• Phase 2 and 3 Placebo Controlled & Long-term Extension Study of Rilzabrutinib in Adults With iCVID to Evaluate Efficacy, Safety, and TolerabilityNot yet recruitingNCT07923305Phase 2/3
• Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)RecruitingNCT07284641Phase 2
• Peripheral Helper T-cells in Common Variable ImmunoDeficiencyRecruitingNCT07255157Not applicable
• Immunoglobulin for Hypogammaglobulinemia Due to Chimeric Antigen Receptor T Cell TherapyRecruitingNCT06989541
• Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and HypogammaglobulinemiaRecruitingNCT06976476Phase 2
• IVIG Boya: Safety, Efficacy, and PharmacokineticsNot yet recruitingNCT06150833Phase 3
• Usage of Spirometry in Managing IgG Therapy in CVID With Airway DiseaseRecruitingNCT05193552Phase 4
• Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung DiseaseRecruitingNCT04925375Phase 2
• Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ImmunityRecruitingNCT04339777Phase 2
• Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesRecruitingNCT02579967Phase 2
• Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency DiseasesEnrolling by invitationNCT01852370Phase 1/2
• Natural History of BronchiectasisRecruitingNCT00943514
• Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation DisordersEnrolling by invitationNCT00895271
• Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationActive, not recruitingNCT03663933Phase 2Results posted
• Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell TransplantationCompletedNCT03513328Phase 1/2Results posted
• Study of Efficacy of CDZ173 in Patients With APDS/PASLICompletedNCT02435173Phase 2/3Results posted
• Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency DiseasesCompletedNCT01963143Phase 3Results posted
• Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency DiseasesCompletedNCT01884311Phase 3Results posted
• Immune Disorder HSCT ProtocolCompletedNCT01821781Phase 2Results posted
• A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary ImmunodeficiencyCompletedNCT01289847Phase 4Results posted
• Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement TherapyCompletedNCT00542997Phase 3Results posted
• Efficacy and Safety of Vivaglobin® in Previously Untreated Patients With Primary ImmunodeficiencyCompletedNCT00520494Phase 4Results posted
• Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)CompletedNCT00322556Phase 3Results posted
• Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases.CompletedNCT00278954Phase 3Results posted
• Leniolisib for Immune Dysregulation in CVIDCompletedNCT06897358Phase 2
• Bronchiectasis Prevalence in Patients With Primary Humoral Immunodefiency in Champagne-Ardenne Region, FranceCompletedNCT06355323Not applicable
• Prediction of Portal Hypertension in Patients With CVID (CVID-pHT)CompletedNCT06145100
• Senolytics Treatment of Interstitial Lung Disease in Common Variable ImmunodeficiencyActive, not recruitingNCT05593588Phase 2
• Composition and Function of Gut Microbiota in Porto-sinusoidal Vascular Disease Associated With Variable Common ImmunodeficiencyStatus unknownNCT05481554
• COVID-19 Vaccine Responses in PIDD SubjectsActive, not recruitingNCT05321407
• GLILD Diagnosed in Children and Young Adults With Common Variable ImmunodeficiencyStatus unknownNCT03648567
• A Study to Evaluate the Benefit of RUCONEST® in Subjects Who Experience ADRs Related to IVIG InfusionsCompletedNCT03576469Phase 4
• Human IgGs and Endothelial Function in Vivo in HumansCompletedNCT03534479Not applicable
• Severe PID With Lymphoproliferation and NeutropeniaCompletedNCT03427593Not applicable
• Improving the Diagnosis of Common Variable Immune DeficiencyCompletedNCT03335605
• The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency DiseaseCompletedNCT03211689Not applicable
• Breadth of Donor Options for People With Inherited Diseases Requiring Allogeneic Hematopoietic Stem Cell Transplant in the Era of Alternative Donor Transplants Using Post-Transplantation CyclophosphamideCompletedNCT03188419
• Assessment of Immunogenicity of Zostavax® in Patients With Antibody Deficiency 60 Years of Age and OlderTerminatedNCT02960399Not applicable
• Treatment of Granulomatous and Lymphocytic Interstitial Lung Disease in Patients With Common Variable ImmunodeficiencyWithdrawnNCT02789397Phase 2
• The Rifaximin Study in CVIDCompletedNCT01946906Phase 4
• Gamma Globulin Observations and Outcomes Database for Patients With Primary Immunodeficiency Disease (GOOD-SHEPARD-PI)TerminatedNCT01883921
• Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune DeficienciesActive, not recruitingNCT01652092Not applicable
• "Prime Boost" Vaccination Strategy Combining Conjugated Anti- Pneumococcal Vaccine (s0) and Polysaccharide Anti- Pneumococcal Vaccine (s4) Compared to Polysaccharide Anti- Pneumococcal Vaccine Alone (s4) In Patients With Common Variable ImmunodeficiencyTerminatedNCT01489618Phase 2
• Lymphocyte Immunophenotyping in Common Variable ImmunodeficiencyCompletedNCT01196702
• Specific IgG Antibody in Patients With Primary Antibody Deficiencies Treated With Subcutaneous ImmunoglobulinCompletedNCT00661401Not applicable
• A Clinical Study of Intravenous ImmunoglobulinCompletedNCT00468273Phase 3
• Studies of Disorders in Antibody Production and Related Primary Immunodeficiency StatesTerminatedNCT00266513
• STA-5326 Meslylate to Treat Gut Inflammation Associated With Common Variable ImmunodeficiencyCompletedNCT00263237Phase 1
• Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency PatientsCompletedNCT00220766Phase 3
• Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)CompletedNCT00168025Phase 3
• Efficacy and Safety of Intravenous Immunoglobulin IVIG-F10 in Patients With Primary Immunodeficiencies (PID)CompletedNCT00168012Phase 3
• Immune System and Gut Abnormalities in Patients With Common Variable Immunodeficiency With and Without Gastrointestinal SymptomsCompletedNCT00015431
• Allogeneic Bone Marrow Transplantation in Patients With Primary ImmunodeficienciesTerminatedNCT00006054Not applicable
• Randomized Study of Polyethylene-Glycol-Conjugated Interleukin 2 in Patients With Common Variable ImmunodeficiencyCompletedNCT00004695Not applicable

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