An interventional study of Traditional physical therapy in Hypertrophic Scar, sponsored by Cairo University. Active, not recruiting at 1 site in Egypt. Open to participants aged 20 Years to 45 Years. Per ClinicalTrials.gov, last updated 2025-04-23.
Sponsored by Cairo University · Not applicable, Interventional, and Other
This study uses a mixed-method design combining a quasi-experimental, single-group pre-post intervention with a methodological validation approach.
Quasi-experimental, single-group pre-post intervention:
Participants will receive a standardized physical therapy protocol targeting scar contracture. After intervention, scar extensibility will be measured using traditional tools (Vancouver Scar Scale, tonometer) and a newly developed image-based method.
Methodological validation approach: The image-based method will be tested for:
121 studies on the registry are indexed under Cicatrix, Hypertrophic; 29 are open to participants now.
This study's enrollment of 90 is above the median of 36 across 104 interventional studies indexed under Cicatrix, Hypertrophic.
Browse Cicatrix, Hypertrophic studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
This study uses a mixed-method design combining a quasi-experimental, single-group pre-post intervention with a methodological validation approach. Participants will receive a standardized physical therapy protocol targeting scar contracture. After intervention, scar extensibility will be measured using traditional tools (Vancouver Scar Scale, tonometer) and a newly developed image-based method. The image-based method will be tested for: * Reliability (test-retest, inter-rater) * Validity (concurrent validity against established tools and construct validity)
Other: Traditional physical therapy
Application of laser three times per week in addition to applying deep friction massage, stretching exercises along with the uses of pressure garment.
Vancouver Scar Scale (VSS)
to evaluate vascularity, pigmentation, pliability, and scar height.
Time frame: Baseline and three months after the intervention
Firmness and pliability at the scar site
Tonometry will be used to assess tissue firmness and pliability at the scar site.
Time frame: Baseline and three months after the intervention
Proposed Image-Based Method
the scar images before and after the intervention will go through three steps: * Image Acquisition: High-resolution digital images of scars will be captured using a standardized protocol (fixed camera settings, lighting, distance). * Image Preprocessing: Images will be converted to grayscale, and regions of interest (ROI) manually or automatically defined. * Image Analysis: The standard deviation (STD) of pixel intensities within the ROI will be calculated as an indicator of tissue extensibility and collagen fiber cross-linking patterns will be detected and quantified using advanced image processing algorithms.
Time frame: Baseline and three months after the intervention
This study is active, not recruiting, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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Cairo University