Cholangitis clinical trials
The registry lists 82 studies for Cholangitis across more than 10 countries. 17 are recruiting or about to start. 34 of them are mainly about Cholangitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Cholangitis, Sclerosing too: 225 studies, 55 open.
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Who runs them
Hepatopancreatobiliary Surgery Institute of Gansu Province (4) · Seoul National University Hospital (3) · Asian Institute of Gastroenterology, India (3) · Assiut University (2) · Xiaoli Fan (2) · Bayer (2) · University Hospital, Geneva (2) · Assistance Publique - Hôpitaux de Paris (2)
What is being tested here
Drugs under test in Cholangitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8
- Dec 2026Impact of Positive Bile Cultures on Plastic Biliary Stent Exchange · Clinical Hospital Colentina
- Dec 2026Efficacy of Fistulotomy for Biliary Cannulation · Coordinación de Investigación en Salud, Mexico
- Dec 2026Composite Index for Outcome Burden in Acute Cholangitis · Asian Institute of Gastroenterology, India
- Jan 2027A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis · Mirum Pharmaceuticals, Inc.
- Jul 2027Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma · Universitätsklinikum Hamburg-Eppendorf
- Jul 2027Biochemical Response and Clinical Outcomes in Patients With PBC · RenJi Hospital
- Oct 2027Rifaximin for Prevention of Recurrent Mild-to-moderate Ascending Cholangitis After Biliary-enteric Anastomosis · Ruijin Hospital
- Nov 2027The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe Itching · RenJi Hospital
Who these studies take
Of the 11 Cholangitis studies recruiting now, 6 (55%) set no upper age limit and 1 (9%) stop at 75 or younger. 2 (18%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (9%) | 1 (9%) |
| 18 | 10 (91%) | 10 (91%) |
| 30 | 10 (91%) | 10 (91%) |
| 40 | 10 (91%) | 10 (91%) |
| 50 | 10 (91%) | 10 (91%) |
| 65 | 10 (91%) | 10 (91%) |
| 75 | 10 (91%) | 10 (91%) |
| 85 | 9 (82%) | 9 (82%) |
Across all 82 studies, recruiting or not: 24% stop at 75 or younger and 15% at 65; 24% take children; 1% are for women only and 0% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cholangitis studies take
Of 21 interventional studies with no phase under Cholangitis, half reached primary completion within 43 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 43 mo32–68 · 21 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 82. Browse all 82 → or search them.
- Composite Index for Outcome Burden in Acute CholangitisRecruitingNCT076671661 country
- Rifaximin for Prevention of Recurrent Mild-to-moderate Ascending Cholangitis After Biliary-enteric AnastomosisNot yet recruitingNCT07895433Phase 4
- Endoscopic Radiofrequency Ablation for Unresectable CholangiocarcinomaRecruitingNCT06175845Not applicable1 country
- The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe ItchingNot yet recruitingNCT07678645Phase 21 country
- EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON StudyNot yet recruitingNCT07655778Not applicable
- Prospective Cohort of Immune Checkpoint Inhibitor-induced HepatitisRecruitingNCT068644811 country
- Sedation Methods in Percutaneous Transhepatic Biliary Drainage: Procedure Quality and RecoveryRecruitingNCT07640243Not applicable1 country
- Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai PortoenterostomyRecruitingNCT05925309Not applicable1 country
- Biochemical Response and Clinical Outcomes in Patients With PBCRecruitingNCT074497931 country
- Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute CholangitisRecruitingNCT07407491Phase 21 country
- Impact of Positive Bile Cultures on Plastic Biliary Stent ExchangeNot yet recruitingNCT07379749Not applicable1 country
- Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar CholangiocarcinomaNot yet recruitingNCT03104569Not applicable1 country
- Cholangitis Definition and Treatment After Kasai Hepatoportoenterostomy for Biliary Atresia: TRACK-BA Study (TRacking Cholangitis Post Kasai in Biliary Atresia)Not yet recruitingNCT071296551 country
- Efficacy of Fistulotomy for Biliary CannulationRecruitingNCT04037007Not applicable1 country
- preGallstep - A Clinical Pilot TrialRecruitingNCT04801238Not applicable1 country
- Quick Large Balloon Dilatation for Removal of Large Bile Duct Stones (SHODBADI)RecruitingNCT05061680Not applicable1 country
- Los Angeles Prospective GI Biliary and EUS SeriesRecruitingNCT021969351 country
- Gluten-free Diet in PSC and IBDCompletedNCT06026449Not applicable1 country
- Secondary Sclerosis Cholangitis ProspectiveActive, not recruitingNCT035667971 country
- Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary CholangitisCompletedNCT04604652Phase 21 country
- A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary CholangitisActive, not recruitingNCT05050136Phase 215 countries
- A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)WithdrawnNCT03678480Phase 2
- Short-course Antibiotics vs Standard Course Antibiotics in Patients With CholangitisCompletedNCT05750966Not applicable1 country
- Sulfasalazine for the Treatment of Primary Sclerosing CholangitisCompletedNCT03561584Phase 21 country
- aScope Single Use ERCP Study- ASSURE StudyCompletedNCT052259091 country
- Urgent (<24 Hours) Versus Early (24 to 48 Hours) ERCP for Patients With Mild and Moderate Acute CholangitisCompletedNCT05920954Not applicable1 country
- ERCP Versus PTBD for Severe Acute Cholangitis Caused by Bile Duct StonesCompletedNCT07064980Not applicable1 country
- Trial of Psychoeducational and Hypnosis Interventions on the Fatigue Associated With PBC in WomenCompletedNCT03630718Not applicable1 country
- Ultrasound-guided Biliary Drainage Improving Prognosis in the Frail and High Risk Elderly PatientsCompletedNCT06960486Not applicable1 country
- Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.CompletedNCT06111872Phase 21 country
- Predictive Factors Associated to Bile Cultures and Antibiogram Resistance in Patients with Laparoscopic CholecystectomyCompletedNCT063143991 country
- A Study to Evaluate the Safety, and Tolerability, and Efficacy of Seladelpar in Patients With PSCTerminatedNCT04024813Phase 23 countries
- Optimal Placement Duration of Pancreatic Duct StentCompletedNCT04691674Not applicable1 country
- Selected Mesenchymal Stromal Cells to Reduce Inflammation in Patients With PSC and AIHActive, not recruitingNCT02997878Phase 1/21 country
- The Necessity of Bile Cultures in Patients With Acute CholangitisActive, not recruitingNCT02601417Not applicable1 country
- NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial IdentificationCompletedNCT061413951 country
- Single Use ERCP Performance -SURE StudyCompletedNCT046710951 country
- Efficacy of Single Use Disposable Elevator Cap (DEC) DuodenoscopyStatus unknownNCT058001711 country
- Outcome of Kasai Portoenterostomy in Biliary Atresia in Upper EgyptCompletedNCT059255431 country
- Antibiotics to Decrease Post ERCP CholangitisStatus unknownNCT03087656Phase 41 country
- Effect of Saline Irrigation in Reducing Choledocholithiasis Recurrence After ERCPCompletedNCT03937037Not applicable1 country
- Effect of Common Bile Duct Stone Clearance Using Saline Irrigation After Stone Removal: A Prospective Randomized Control Trial.CompletedNCT05639816Not applicable1 country
- Biliary Candidiasis - Optimization of Diagnostics and TherapyCompletedNCT011095501 country
- Definition for Biliary Atresia Associated Cholangitis After SurgeryStatus unknownNCT054643031 country
- Peri Kasai Portoenterostomy Anchoring of the Jejunal LoopStatus unknownNCT04961034Not applicable1 country
- Antibiotics Treatment of Cholangitis Post-Kasai PortoenterostomyCompletedNCT04370145Phase 41 country
- Evaluation of MRI Sequences for Ultra-rapid Acquisition of Bile Ducts ImagesTerminatedNCT03852836Not applicable1 country
- Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap SyndromeStatus unknownNCT02936596Not applicable1 country
- The Comparisons of One-stage Stone Removal in Mild and Moderate CholangitisCompletedNCT03754491Not applicable1 country
- Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With CholangioscopyWithdrawnNCT025439571 country