Charcot-Marie-Tooth Disease: all 113 studies

Page 1 of 2. Open to participants first (37), then studies with results posted, then the rest; newest registration first within each.

• Muscle MRI Fat Fraction Before Surgery to Predict Strength Recovery After Foot-Drop Surgery in Charcot-Marie-Tooth DiseaseNot yet recruitingNCT07894536
• Clinical, Electrophysiological and Genetic Characteristics of Hereditary and Inflammatory Polyneuropathies in FranceNot yet recruitingNCT07851844
• Clinical Trial Evaluating the Impact of an Intensive Rehabilitation Program Combined With Tendon Vibratory Stimulation on Functional Balance in Individuals With Charcot-Marie-Tooth Disease Type 1ARecruitingNCT07726043Not applicable
• Ultrasound-Guided Nerve Hydrodissection for Diabetic Lower Limb Entrapment NeuropathyRecruitingNCT07625020Not applicable
• Physical Activity Level at Home in CMT1A Patients: Wearable Sensor AssessmentNot yet recruitingNCT07591779
• TREMOR IN CHARCOT-MARIE-TOOTHRecruitingNCT07570459
• AUTONOMOUS DISORDERS IN CMTRecruitingNCT07570446
• A Multi-omic Approach to the Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease (CMT1A)RecruitingNCT07476365
• Studying Nerve Function and Structure in Charcot-Marie-Tooth Disease, Anti-MAG Neuropathy and CIDPRecruitingNCT07461896
• Walking Function Outcomes Following Surgical Correction With Rehabilitation Versus Physical Therapy Alone in Charcot-Marie-Tooth Disease: A Bidirectional Cohort StudyNot yet recruitingNCT07432035
• Assessment of a Portable Digital Device for Quantified Analysis of Markerless Walking in Volunteers With Neuromuscular Diseases or Asymptomatic VolunteersRecruitingNCT07321977Not applicable
• CMT Gait, Mobility, Balance - AOFAS GrantRecruitingNCT07188415Not applicable
• Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)RecruitingNCT07152197Not applicable
• A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of EDK060 in Adults With CMT1A.RecruitingNCT07140614Phase 1
• Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic PathologyRecruitingNCT07136844Not applicable
• The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in ChildrenRecruitingNCT07090057Not applicable
• Genotype/Phenotype Correlation of MORC2 MutationsRecruitingNCT07038239
• High-Tech Rehabilitation Pathway for Chronic Adult Neuromuscular Diseases - Fit4MedRob-Chronic MND ProjectRecruitingNCT06881979Not applicable
• Longitudinal Quantitative Neuromuscular MRI in Neuropathic PatientsRecruitingNCT06845644Not applicable
• Longitudinal Biomarkers With Selected Outcome Measures In CMTRecruitingNCT06794489
• Personalized Training for People With Rare Neuromuscular DisordersRecruitingNCT06708468Not applicable
• Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)RecruitingNCT06669949
• Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular DiseasesRecruitingNCT06666816
• Evaluate the Safety and Efficacy of EN001 in Patients With Charcot-Marie-Tooth Disease Type 1A(CMT1A) (Phase 1b: Open-label, Dose-escalation, Single-center; Phase 2a: Randomized, Double-blind, Placebo-controlled, Multicenter)RecruitingNCT06328712Phase 1/2
• Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for IPSC Generation and BiobankingRecruitingNCT06203093
• Topical Cannabidiol for Treating Carpal Tunnel SyndromeNot yet recruitingNCT06108349Phase 2
• A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism DisordersRecruitingNCT06092346
• Assessments in Patients With Muscular Pathology and in Control Subjects : The ActiLiège Next StudyRecruitingNCT05982119Not applicable
• Natural History Study for Charcot Marie Tooth DiseaseRecruitingNCT05902351
• Sodium Channel Mutations in Patient With the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)RecruitingNCT05877274
• Research of SORD-CMT Natural History and Epalrestat TreatmentNot yet recruitingNCT05777226Phase 2
• A Pilot Study to Explore the Use of Skin Biopsy as Diagnostic Tool in Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)RecruitingNCT05678127Not applicable
• A Registered Cohort Study on Charcot-Marie-Tooth DiseaseRecruitingNCT04010188
• The Myelin Disorders Biorepository ProjectRecruitingNCT03047369
• Inherited Retinal Degenerative Disease RegistryRecruitingNCT02435940
• Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2RecruitingNCT01193088
• Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and OthersRecruitingNCT01193075
• Extension Study to Evaluate the Long-Term Effects of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy (FSHD) and Charcot-Marie Tooth (CMT) Disease Types 1 and X (CMT1 and CMTX)TerminatedNCT03943290Phase 2Results posted
• Study of ACE-083 in Patients With Charcot-Marie-Tooth DiseaseTerminatedNCT03124459Phase 2Results posted
• SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot StudyCompletedNCT02967679Phase 2Results posted
• LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for LeukodystrophiesCompletedNCT02699190Results posted
• Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT)CompletedNCT02579759Phase 3Results posted
• Mexiletine for Muscle Cramps in Charcot Marie Tooth DiseaseCompletedNCT02561702Phase 2Results posted
• Phase II, Randomized, Placebo-controlled Trial in Patients With Charcot-marie-tooth Disease Type 1ACompletedNCT01401257Phase 2Results posted
• Kinesio Taping for Pain, Median Nerve Morphology, and Quality of Life in Patients With Carpal Tunnel SyndromeCompletedNCT07741708Not applicable
• Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular DiseaseActive, not recruitingNCT07478172Not applicable
• High-Intensity Laser Therapy in Carpal Tunnel Syndrome: Clinical, Sonographic, and Electrophysiological OutcomesCompletedNCT07414069Not applicable
• "Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients"CompletedNCT07408596
• The Effectiveness of Low-Level Laser Therapy in the Treatment of Meralgia ParestheticaCompletedNCT07335822Not applicable
• Median Nerve Decompression for Complex Regional Pain Syndrome: A Clinical StudyCompletedNCT07263256Not applicable
• Treatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual PatientActive, not recruitingNCT07223632Phase 1/2
• Hydrodissection in Carpal Tunnel SyndromeCompletedNCT07207460Not applicable
• Confirmatory Study of Govorestat in CMT-SORDWithdrawnNCT07191912Phase 3
• Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A DiseaseActive, not recruitingNCT07049588Not applicable
• High Intensity Exercise and Improving Physical Activity Among People With Neurologic DysfunctionCompletedNCT06945835Not applicable
• EVALUATION OF SERUM INFLAMMATORY CYTOKINE CONCENTRATION IN HEREDITARY SENSITIVOMOTOR NEUROPATHIESCompletedNCT06808581Not applicable
• Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth DiseaseCompletedNCT06482437Phase 2
• Comparing Efficacies of Median Nerve Hydrodissection With Dexamethasone and Dextrose in Carpal Tunnel SyndromeCompletedNCT06400433Not applicable
• Radiofrequency Ablation of the Superior Cluneal NerveCompletedNCT06240000Not applicable
• Evaluate the Safety and Potential Efficacy of Human Wharton's Jelly-derived Mesenchymal Stem Cells With Charcot-Marie-Tooth Disease Type 1ECompletedNCT06218134Not applicable
• Polyneuropathy, Impairments and Physical Activity - The PolyImPAct StudyActive, not recruitingNCT06040567
• The Safety and Tolerability of CLZ-2002 in Patients With Charcot-Marie Tooth Disease.CompletedNCT05947578Phase 1
• Hearing and Balance Disorders in Peripheral NeuropathyTerminatedNCT05827419
• Baby Detect : Genomic Newborn ScreeningCompletedNCT05687474
• Soft Tissue Massage Along With Mobilization Technique on Symptoms and Functional Status of Carpal Tunnel SyndromeStatus unknownNCT05466162Not applicable
• Study on the Efficacy of Infiltration of Upper Cluneal Nerves in Chronic Pain Related to Cluneal SyndromeWithdrawnNCT05423132Not applicable
• Determine the Safety and Dose of EN001 in Patients With Charcot-Marie-Tooth Disease (CMT) Type 1ACompletedNCT05333406Phase 1
• The Frequency of Superior Cluneal Nerve Entrapment Diagnosed With Ultrasound Guided Nerve BlockCompletedNCT05303597Not applicable
• Fall Risk Assessment in a Population of Charcot-Marie-Tooth Disease Type 1A (CMT 1A) by Timed Up and Go TestCompletedNCT05142059Not applicable
• NT-3 Levels and Function in Individuals With CMTTerminatedNCT05011006
• Observational Study of Neuromuscular Function in CMT Type 1&2 and Healthy ControlsCompletedNCT04980807
• Genetics of Charcot-Marie-Tooth Dystrophy and Related DiseasesStatus unknownNCT04967716
• High Intensity Laser Therapy in Carpal Tunnel SyndromeCompletedNCT04949373Not applicable
• NuroSleeve Powered Brace & Stimulation System to Restore Arm FunctionActive, not recruitingNCT04798378Not applicable
• Irisin Levels in Patients With Charcot-Marie-Tooth (CMT) DiseaseCompletedNCT04786522
• Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A PatientsActive, not recruitingNCT04762758Phase 3
• Ultrasound Localization and Guided Injection for Superior Cluneal Nerve EntrapmentStatus unknownNCT04478344Not applicable
• Physical Activity in Persons With Charcot-Marie-Tooth: Developing a Measurement InstrumentStatus unknownNCT04461613Not applicable
• Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular PatientsCompletedNCT04283175
• Posturography-NeuropathyCompletedNCT04154540Not applicable
• A Natural History Study of Charcot-Marie-Tooth 4J (CMT4J)TerminatedNCT03810508
• The Impact of Charcot-Marie-Tooth Disease in the Real WorldCompletedNCT03782883
• Change in MUNIX in Patients With CMT1A Undergoing a Home Ankle Strengthening Program Versus Standard of CareCompletedNCT03715283Not applicable
• Muscle MRI in Charcot Mary Tooth Disease: a Prospective Cohort StudyStatus unknownNCT03550300
• Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1AWithdrawnNCT03520751Phase 1/2
• Diffusion Tensor Imaging in Chronic Inflammatory Demyelinating Polyneuropathy (PIDC)CompletedNCT03460951
• Quantification of Nerve Stiffness in NeuropathiesCompletedNCT03397303Not applicable
• Biomarkers and Validation of Selected Outcome Measures (CMTBiomarker)CompletedNCT03386266
• Effect of Orthoses and Underfoot Vibration on Balance in NeuropathyStatus unknownNCT03278093
• A Study to Assess the Safety and Effectiveness of FLX-787 in Subjects With Charcot-Marie-Tooth Disease Experiencing Muscle Cramps.TerminatedNCT03254199Phase 2
• Efficacy of Keyhole Approach to Carpal Tunnel Syndrome Under Ambulatory StrategyCompletedNCT03062722Not applicable
• Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1AActive, not recruitingNCT03023540Phase 3
• BALTiC Study: A Feasibility Analysis of Home Based BALance Training in People With Charcot-Marie-Tooth DiseaseCompletedNCT02982343Not applicable
• Charcot-Marie-Tooth Disease (CMT) Infant Scale (INC-6611)Status unknownNCT02979145
• Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited NeuropathiesCompletedNCT02788734
• Tools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and BiomarkersActive, not recruitingNCT02596191Not applicable
• Genetics of Pediatric-Onset Motor Neuron and Neuromuscular DiseasesCompletedNCT02532244
• An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) PatientsCompletedNCT02429947
• Driving Ability in Patients With CMT 1ACompletedNCT02357355Not applicable
• Suprascapular Neuropathy in the Setting of Rotator Cuff Tears: Results of Arthroscopic TreatmentCompletedNCT02318381Not applicable

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