An observational study in CMT - Charcot-Marie-Tooth Disease, Peripheral Neuropathy and Hereditary Peripheral Neuropathy, sponsored by St George's, University of London. Status unknown at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-01-22.
Sponsored by St George's, University of London · Observational
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Among 11 studies in Charcot-Marie-Tooth Disease with a site in United Kingdom — 2 open to participants now, 3 under way, 1 of them phase 3. Charcot-Marie-Tooth Disease · United Kingdom.
Among the 11 studies in Charcot-Marie-Tooth Disease with a site in United Kingdom, this one is one of 2 that started in 2017, is one of 8 observational ones, and was the 9th registered.
113 studies on the registry are indexed under Charcot-Marie-Tooth Disease; 37 are open to participants now.
Browse Charcot-Marie-Tooth Disease studies →2 of the 11 studies in Charcot-Marie-Tooth Disease with a site in United Kingdom are open now. Recruiting first, the newest first:
University of Iowa · Sites in United Kingdom, United States, Australia and 3 more countries
Healthy volunteers
Michael Shy · Sites in United Kingdom, United States, Australia and 3 more countries
Healthy volunteers
A study can be open while its sites in United Kingdom have not opened yet or have stopped. Only those recruiting at a site in United Kingdom →
Of the 31 Charcot-Marie-Tooth Disease studies recruiting now, 14 (45%) set no upper age limit and 13 (42%) stop at 75 or younger; 14 take children under 18; 13 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
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11 studies; the count open now beside each. This study's row is marked.
First in 2010; this study’s year is marked. 2 started in 2017.
This study's planned enrollment of 15 is below the median of 120 across 47 observational studies indexed under Charcot-Marie-Tooth Disease.
Median enrollment 187 across the 3 interventional studies, 807 across the 8 observational. Of the 6 that completed or were terminated, 1 (17%) have results posted.
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1 of 11 have an industry lead sponsor. The 7 most frequent:
St George's, University of London is the lead sponsor of 106 studies on the registry; 12 are open to participants now.
St George's, University of London has 1 study filed under Charcot-Marie-Tooth Disease — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 11 studies in Charcot-Marie-Tooth Disease with a site in United Kingdom, from their registry updates:
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A cross-sectional study which will look at the effects of AFO's and vibrating insoles on balance performance in people with CMT disease.
Balance impairments and falls are more common in people who have Charcot Marie Tooth disease (CMT) than in people without the condition. CMT is a condition which affects the nerves causing a variety of symptoms including sensation impairments and weakness. The impairments are usually most evident in the feet and hands, but they can progress very slowly moving closer to the trunk. Ankle Foot Orthoses (AFO's) are often prescribed to help with walking and daily function. So far the effects of AFO's on standing balance in people who have CMT have not been looked at. Insoles are also often prescribed to realign foot deformity and reduce pain. Insoles which give a vibratory input have had a positive impact on walking in older people but have not been looked at in balance and in CMT. Insoles which give a vibration feedback to the sole of the foot when worn have been designed. This study will look at whether the use of AFO's and the vibratory insoles have an effect on standing balance in people with CMT or related peripheral neuropathy. Balance measurements will be taken in a single session comparing a variety of postures. Patients will be recruited from neurology outpatient clinics at the National Hospital of Neurology and Neurosurgery.
Mobile adults who have CMT with both motor and sensory symptoms.
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Exclusion Criteria:
Posturography
CODA motion movement analysis for postural sway Measures will be taken in all conditions with feet together and feet apart. Both conditions will also be looked at with eyes open and eyes closed.
Time frame: 30 second caputer in a variety of conditions
force measures
AMTI forceplate for centre of pressure . Measures will be taken in all conditions with feet together and feet apart. Both conditions will also be looked at with eyes open and eyes closed.
Time frame: 30 second caputer in a variety of conditions
Started Oct 2017 (actual). Primary completion is estimated for Feb 2019, 16 months after the start.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.
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St George's, University of London →