An observational study in Neuromuscular Diseases, Hemiparesis and Charcot-Marie-Tooth Disease, sponsored by Assistance Publique - Hôpitaux de Paris. Completed at 1 site in France. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-04.
Sponsored by Assistance Publique - Hôpitaux de Paris · Observational
Among 23 studies in Charcot-Marie-Tooth Disease with a site in France — 6 open to participants now, 10 under way, 2 of them phase 3. Charcot-Marie-Tooth Disease · France.
Among the 23 studies in Charcot-Marie-Tooth Disease with a site in France, this one is one of 3 that started in 2021, is one of 6 observational ones, and was the 11th registered.
113 studies on the registry are indexed under Charcot-Marie-Tooth Disease; 38 are open to participants now.
This study's enrollment of 77 is below the median of 120 across 47 observational studies indexed under Charcot-Marie-Tooth Disease.
Browse Charcot-Marie-Tooth Disease studies →6 of the 23 studies in Charcot-Marie-Tooth Disease with a site in France are open now, in 1 country. Each count lists the studies.
Of the 32 Charcot-Marie-Tooth Disease studies recruiting now, 14 (44%) set no upper age limit and 14 (44%) stop at 75 or younger; 14 take children under 18; 13 take healthy volunteers.
This study: 18 Years and older · all sexes · healthy volunteers too.
The full table on the hub →23 studies; the count open now beside each. This study's row is marked.
First in 2010; this study’s year is marked. 3 started in 2021.
Median enrollment 67 across the 17 interventional studies, 53 across the 6 observational. Of the 12 that completed or were terminated, 3 (25%) have results posted.
3 of 23 have an industry lead sponsor. The 10 most frequent:
Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,592 studies on the registry; 1,033 are open to participants now.
Assistance Publique - Hôpitaux de Paris has 2 studies filed under Charcot-Marie-Tooth Disease — fewer than ten, so there is no comparison to draw.
6 of the studies in Charcot-Marie-Tooth Disease with a site in France that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07321977Institut de Myologie, FranceAssessment of a Portable Digital Device for Quantified Analysis of Markerless Walking in Volunteers With Neuromuscular Diseases or Asymptomatic Volunteers | 2026-12-31 |
| NCT07591779University Hospital, LimogesPhysical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment | 2027-04-15 |
| NCT02596191Assistance Publique Hopitaux De MarseilleTools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and Biomarkers | 2027-05-05 |
| NCT06845644Assistance Publique Hopitaux De MarseilleLongitudinal Quantitative Neuromuscular MRI in Neuropathic Patients | 2027-05-23 |
| NCT07038239Hospices Civils de LyonGenotype/Phenotype Correlation of MORC2 Mutations | 2027-06 |
Among the 23 studies in Charcot-Marie-Tooth Disease with a site in France, from their registry updates:
The instrumental evaluation of standing postural control by posturographic analysis supplements the clinical evaluation and, as such, is recommended by the French National Authority for Health (HAS 2007). The quantitative data obtained after a standardized postural examination appear relevant for the longitudinal follow-up of neuromuscular patients and hemiparetic patients. Neuro muscular (NM) diseases are progressive, these instrumental evaluations can highlight a deterioration or stabilization of postural control possibly not observable with the scores on clinical scales.
The K-Force Plates, recently developed appear to be an interesting alternative to the stabilometry platforms currently used. Static and dynamic conditions in upright position are tested. Moreover, posturologic, kinematics data and clinical scores are correlated to increase understanding of strategies during postural control tasks in patients with stroke and in patients with NM disorders.
To date, no clinical validation study of these K-Force Plates force platforms has been proposed. The investigator hypothesize that the data obtained by the Plates are comparable to the measurements made by the reference tool, the AMTI platforms during a static and dynamic posturographic examination in MNM, hemiparetic and healthy subjects. The strategies of the patients (stroke and NM) during the dynamic task are also explored with kinematic analysis in correlation with data from force platforms and clinical scores.
113 studies on the registry are indexed under Charcot-Marie-Tooth Disease; 38 are open to participants now.
This study's enrollment of 77 is below the median of 120 across 47 observational studies indexed under Charcot-Marie-Tooth Disease.
Browse Charcot-Marie-Tooth Disease studies →Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,592 studies on the registry; 1,033 are open to participants now.
Compared within Charcot-Marie-Tooth Disease, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Neuromuscular Diseases. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Single stroke hemiparetic patient, or patient with neuro-muscular disease, or healthy subject free of neurological disorder and other disease.
"Eligible couples must present all the following criteria :
To be included, patient should not present any of the following criteria :
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Posturological examination on KPlates and AMTI platforms · Other: Berg Balance Scale (BBS)
Other: Posturological examination on KPlates and AMTI platforms · Other: Berg Balance Scale (BBS)
Other: Posturological examination on KPlates and AMTI platforms
By an unique evaluator
Falls and fera of falling, motor and sensory impairments
Evaluate the concurrent validity of K-Force Plates (K-Invent) force platforms in comparison with reference platforms (AMTI) for posturological examination in static and dynamic conditions of MNM subjects (CMT), hemiparetic subjects and healthy subjects.
Intraclass correlation coefficient (ICC) of the mean velocity of the pressure center (CP) with the both platforms during the posturological examination. The average of 3 tests carried out will be taken
Time frame: Day 0
Evaluate convergent validity with the reference scale for the assessment of equilibrium disorders
Berg's equilibrium rating scale (0-56) ( score at 0: worse outcome)
Time frame: Day 0
Compare the posturology and kinematics between stroke and healthy subjects and between NM and healthy subjects
Explore the relations between the posturology, kinematics and clinical parameters in stroke population and in NM population.
Time frame: Day 0
Ran from Apr 2021 to primary completion in Feb 2024, 34 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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