Carcinosarcoma clinical trials
The registry lists 60 studies for Carcinosarcoma across more than 10 countries. 12 are recruiting or about to start. 24 of them are mainly about Carcinosarcoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Cancer Institute (NCI) (16) · Memorial Sloan Kettering Cancer Center (5) · Mayo Clinic (4) · Leap Therapeutics, Inc. (2) · Australia New Zealand Gynaecological Oncology Group (2) · NRG Oncology (1) · Ohio State University Comprehensive Cancer Center (1) · pharmaand GmbH (1)
What is being tested here
Drugs under test in Carcinosarcoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Mirvetuximab soravtansine | 1 | 0 | 1 |
| Neoantigen Peptide Vaccine | 1 | 0 | 1 |
| Dordaviprone | 1 | 0 | 1 |
| Nivolumab | 0 | 0 | 5 |
| Paclitaxel | 0 | 0 | 4 |
| Carboplatin | 0 | 1 | 4 |
| Cediranib | 0 | 0 | 2 |
| Pembrolizumab | 0 | 2 | 2 |
| Ceralasertib | 0 | 0 | 2 |
| Capivasertib | 0 | 0 | 1 |
Drug classes tested here Immune checkpoint inhibitors 10 · Tyrosine kinase inhibitors (TKIs) 6 · PARP inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8, phase 3 first
- Nov 2026Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer · Phase 3 · University of Utah
- Jun 2027Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib · Phase 3 · ARCAGY/ GINECO GROUP
- Dec 2026A Study of Pembrolizumab With Lenvatinib in Women With Advanced Uterine Carcinosarcoma · Memorial Sloan Kettering Cancer Center
- Feb 2027Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers · National Cancer Institute (NCI)
- Mar 2027Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial · National Cancer Institute (NCI)
- May 2027Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform · Mayo Clinic
- Jul 2027Agnostic Therapy in Rare Solid Tumors · Instituto do Cancer do Estado de São Paulo
- Sep 2027Study of BMS-986205 and Nivolumab in Endometrial Cancer or Endometrial Carcinosarcoma That Has Not Responded to Treatment · Memorial Sloan Kettering Cancer Center
Who these studies take
Of the 11 Carcinosarcoma studies recruiting now, 11 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 3 (27%) take children under 18. 5 (45%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (9%) | 1 (9%) |
| 18 | 11 (100%) | 6 (55%) |
| 30 | 11 (100%) | 6 (55%) |
| 40 | 11 (100%) | 6 (55%) |
| 50 | 11 (100%) | 6 (55%) |
| 65 | 11 (100%) | 6 (55%) |
| 75 | 11 (100%) | 6 (55%) |
| 85 | 11 (100%) | 6 (55%) |
Across all 60 studies, recruiting or not: 3% stop at 75 or younger and 0% at 65; 15% take children; 67% are for women only and 0% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Carcinosarcoma studies take
Of 22 phase 2 interventional studies under Carcinosarcoma, half reached primary completion within 74 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 74 mo42–111 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 60. Browse all 60 → or search them.
- Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial CancerRecruitingNCT05646316Phase 32 countries
- A Study of PHST001 in Advanced Solid TumorsRecruitingNCT06840886Phase 11 country
- Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT TrialRecruitingNCT06639074Phase 21 country
- Recurrent Ovarian CarcinoSarcoma Anti-pd-1 NiraparibRecruitingNCT03651206Phase 2/33 countries
- Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid TumorsRecruitingNCT05269381Phase 1/21 country
- Web-based Lifestyle Program, mHealth and EMA Intervention, to Improve Weight Loss in Rural Stage I-III Postmenopausal Breast and Endometrial Cancer Survivors, HERO-C TrialNot yet recruitingNCT07723235Not applicable1 country
- Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote MonitoringRecruitingNCT05500391Phase 21 country
- Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic PlatformRecruitingNCT063496421 country
- GISAR German Interdisciplinary Sarcoma RegistryRecruitingNCT041228721 country
- ONC201 and Atezolizumab in Obesity-Driven Endometrial CancerRecruitingNCT05542407Phase 11 country
- Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial CancerRecruitingNCT03422198Phase 31 country
- Longitudinal Sample Collection to Investigate Adaptation and Evolution of Ovarian High-grade Serous CarcinomaRecruitingNCT055378441 country
- Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib AloneActive, not recruitingNCT03660826Phase 22 countries
- Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial CancerActive, not recruitingNCT03914612Phase 35 countries
- Study of BMS-986205 and Nivolumab in Endometrial Cancer or Endometrial Carcinosarcoma That Has Not Responded to TreatmentActive, not recruitingNCT04106414Phase 21 country
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 21 country
- Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial CancersActive, not recruitingNCT05691504Phase 11 country
- Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial CancerActive, not recruitingNCT00977574Phase 21 country
- Cabozantinib S-malate and Nivolumab in Treating Patients With Advanced, Recurrent, or Metastatic Endometrial CancerActive, not recruitingNCT03367741Phase 22 countries
- Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH TrialActive, not recruitingNCT04704661Phase 11 country
- EPOCH: Eribulin and Pembrolizumab in Ovarian/Uterine CarcinosarcomaCompletedNCT05619913Phase 23 countries
- Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial CancerActive, not recruitingNCT04214067Phase 32 countries
- Nivolumab and Ipilimumab in Treating Patients With Rare TumorsActive, not recruitingNCT02834013Phase 22 countries
- A Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid TumorsTerminatedNCT05949632Phase 1/21 country
- A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial CarcinosarcomaCompletedNCT05156268Phase 21 country
- A Study of Pembrolizumab With Lenvatinib in Women With Advanced Uterine CarcinosarcomaActive, not recruitingNCT05147558Phase 21 country
- ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or no LossActive, not recruitingNCT04065269Phase 22 countries
- (VELA) Study of BLU-222 in Advanced Solid TumorsTerminatedNCT05252416Phase 13 countries
- Expanded Access Use of DKN-01 for the Treatment of Advanced Solid TumorsNo longer availableNCT046812481 country
- Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus.CompletedNCT04458597Not applicable1 country
- A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial Endometrial or Epithelial Ovarian Cancer or CarcinosarcomaCompletedNCT03395080Phase 21 country
- Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian CancerWithdrawnNCT06393751Phase 1/2
- ZW25 in Women With Endometrial CancersCompletedNCT04513665Phase 21 country
- A Study of Nivolumab in Selected Uterine Cancer PatientsCompletedNCT03241745Phase 21 country
- A Phase 1b/2 Study of Rebastinib (DCC-2036) in Combination With Paclitaxel in Patients With Advanced or Metastatic Solid TumorsTerminatedNCT03601897Phase 1/21 country
- Pazopanib Vs. Pazopanib Plus GemcitabineActive, not recruitingNCT02203760Phase 21 country
- Paclitaxel/Carboplatin + Galunisertib for Patients With Carcinosarcoma of the Uterus or OvaryCompletedNCT03206177Phase 11 country
- Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological CancersCompletedNCT02020707Phase 11 country
- A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR GenesTerminatedNCT04171700Phase 21 country
- Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Uterine CancerTerminatedNCT01367301Not applicable1 country
- Use of Electrical Impedance Spectroscopy (EIS) for Early Diagnosis of Skin DamageTerminatedNCT046887491 country
- Camrelizumab Combined With Apatinib in the Treatment of Advanced Sarcomatoid Carcinoma or CarcinosarcomaStatus unknownNCT05265793Phase 21 country
- Does Cediranib With Paclitaxel, or Cediranib and Olaparib, Treat Advanced Endometrial Cancer Better Than Paclitaxel?Status unknownNCT03570437Phase 21 country
- Nivolumab for Recurrent/Metastatic CarcinosarcomaStatus unknownNCT05224999Phase 21 country
- Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed, Persistent or Recurrent Uterine, Ovarian, Fallopian Tube, or Peritoneal Cavity CancerStatus unknownNCT00954174Phase 32 countries
- Trial On Trabectedin In The Treatment Of Advanced Uterine And Ovarian Carcinosarcoma (CS)CompletedNCT02993705Phase 21 country
- Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or ChemotherapyWithdrawnNCT03933761Phase 2
- Cabozantinib Plus Nivolumab and Ipilimumab in Women With Recurrent Gynecologic CarcinosarcomaWithdrawnNCT04149275Phase 21 country
- Sunitinib Malate in Treating Patients With Recurrent or Metastatic Endometrial CancerCompletedNCT00478426Phase 22 countries
- Pazopanib Hydrochloride in Treating Patients With Recurrent or Persistent Uterine CancerCompletedNCT01247571Phase 21 country