Carcinoma, Squamous Cell: all 1,779 studies

Page 5 of 18. Open to participants first (409), then studies with results posted, then the rest; newest registration first within each.

• Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCCRecruitingNCT03370406Phase 1
• Prognostic Impact of Tumor Growth Velocity in Head and Neck Squamous Cell Carcinoma Treated by Radio(Chemo)TherapyNot yet recruitingNCT02990936
• A Study on Tumor Budding Guiding Individualized Surgical Planning of Early-stage Oral Squamous Cell Carcinoma.RecruitingNCT02743832Not applicable
• Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With PathologyRecruitingNCT02507141
• Cyclin D1 Based TPF Induction Chemotherapy for Oral Squamous Cell Carcinoma Patients at Clinical N2 StageRecruitingNCT02290145Phase 2
• GDF15 Based TPF Induction Chemotherapy for OSCC PatientsRecruitingNCT02285530Phase 2
• Collection of Plasma Samples for Squamous Cell Carcinoma of the Head and Neck PatientsRecruitingNCT02139020
• T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung CancerRecruitingNCT02133196Phase 2
• Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction DesignRecruitingNCT02128906Phase 2
• Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell CarcinomaTerminatedNCT05461794Phase 2Results posted
• Bempegaldesleukin (NKTR-214) With Radiation and Anti-PD-1 Immunotherapy for Head and Neck Squamous Cell CarcinomaTerminatedNCT04936841Phase 2Results posted
• Neoadjuvant Imiquimod Immunotherapy for Oral CancerCompletedNCT04883645Early Phase 1Results posted
• Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.TerminatedNCT04812535Phase 2Results posted
• Neoadjuvant Study of PD-1 Inhibitor Pembrolizumab in PD-1 Naive Cutaneous Squamous Cell Carcinoma (cSCC)Active, not recruitingNCT04808999Phase 2Results posted
• Study of Ruxolitinib in Solid Organ Transplant Recipients With Advanced Cutaneous Squamous Cell CarcinomaTerminatedNCT04807777Phase 2Results posted
• Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Recurrent or Metastatic Esophageal Squamous Cell CarcinomaCompletedNCT04732494Phase 2Results posted
• Neoadjuvant Atezolizumab in Surgically Resectable Advanced Cutaneous Squamous Cell CarcinomaCompletedNCT04710498Phase 2Results posted
• Optimized Diffusion-Weighted Imaging for the Evaluation of Post-Treatment Squamous Cell Carcinoma in the Neck: Comparative Study With FDG PET/CTTerminatedNCT04685798Not applicableResults posted
• Phase 2 Study of OBP-301 (Telomelysin™) in Combination With Pembrolizumab and SBRT in Patients With HNSCC With Inoperable, Recurrent or Progressive DiseaseTerminatedNCT04685499Phase 2Results posted
• Neoadjuvant PD-1 Blockade in Resectable Oral Squamous Cell CarcinomaCompletedNCT04649476Phase 2Results posted
• Enoblituzumab Plus Retifanlimab or Tebotelimab in Head and Neck CancerTerminatedNCT04634825Phase 2Results posted
• CMP-001 in Combination With Pembrolizumab in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT04633278Phase 2Results posted
• Study of NKTR 255 in Combination With Cetuximab in Solid TumorsCompletedNCT04616196Phase 1/2Results posted
• The Effectiveness of High Resolution Microendoscopy for People Living With HIVCompletedNCT04563754Phase 1/2Results posted
• Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous Cell CancerCompletedNCT04555837Phase 1/2Results posted
• A Study in the United States Using Electronic Medical Records (EMR) to Assess Effectiveness of Afatinib (Gilotrif) Following Pembrolizumab and Chemotherapy in the Treatment of Metastatic Squamous Cell Carcinoma of the LungCompletedNCT04552535Results posted
• Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With CisplatinCompletedNCT04541355Phase 2Results posted
• Ph1 Study of SL-172154 Administered Intratumorally in Subjects With Squamous Cell Carcinoma of the Head and Neck or SkinTerminatedNCT04502888Phase 1Results posted
• A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)CompletedNCT04489888Phase 4Results posted
• Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).CompletedNCT04472429Phase 3Results posted
• A Study of NM21-1480 in Adult Patients With Advanced Solid TumorsTerminatedNCT04442126Phase 1/2Results posted
• Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT04428333Phase 3Results posted
• Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for SurgeryActive, not recruitingNCT04391049Phase 1Results posted
• Cemiplimab in AlloSCT/SOT Recipients With CSCCCompletedNCT04339062Phase 1/2Results posted
• Study to Assess the Efficacy and Safety of Nivolumab in Combination With Paclitaxel in Subjects With Head and Neck Cancer Unable for Cisplatin-based Chemotherapy (NIVOTAX)CompletedNCT04282109Phase 2Results posted
• Cemiplimab-rwlc for Unresectable Locally Recurrent and/or Metastatic CSCCTerminatedNCT04242173Phase 2Results posted
• Efficacy of INCMGA00012 in Penile Squamous Cell Carcinoma (ORPHEUS)CompletedNCT04231981Phase 2Results posted
• Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell CancerTerminatedNCT04220775Phase 1/2Results posted
• A Study of Duvelisib in Combination With Pembrolizumab in Head and Neck CancerTerminatedNCT04193293Phase 1/2Results posted
• 1922GCCC: Pembro and Bavituximab for Squamous Cell Carcinoma of Head and NeckActive, not recruitingNCT04150900Phase 2Results posted
• Melatonin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response in Locally Advanced Oral Squamous Cell CarcinomaCompletedNCT04137627Phase 3Results posted
• Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 (PD-L1) Positive Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT04128696Phase 3Results posted
• Addition of SNS-301 to Checkpoint Inhibitor Treatment in Metastatic/Recurrent SCCHNTerminatedNCT04034225Phase 1/2Results posted
• A Study of Ladiratuzumab Vedotin in Advanced Solid TumorsTerminatedNCT04032704Phase 2Results posted
• Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLCCompletedNCT03989115Phase 1/2Results posted
• De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal CancerActive, not recruitingNCT03952585Phase 2/3Results posted
• De-Escalation Therapy for Human Papillomavirus Negative DiseaseCompletedNCT03944915Phase 2Results posted
• SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or LymphomasCompletedNCT03894618Phase 1Results posted
• Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHNCompletedNCT03878979Phase 2Results posted
• Topical Remetinostat Gel as Neoadjuvant Therapy in Patients With Squamous Cell Carcinoma (SCC)TerminatedNCT03875859Phase 2Results posted
• Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and NeckTerminatedNCT03854032Phase 2Results posted
• Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)CompletedNCT03845296Phase 2Results posted
• Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)TerminatedNCT03833167Phase 3Results posted
• Optimizing Antitumor Immunity Using Plasmid Electroporation, Pembrolizumab, and EpacadostatTerminatedNCT03823131Phase 2Results posted
• A Phase I/II Clinical Trial of PepCan in Head and Neck Cancer PatientsCompletedNCT03821272Phase 1/2Results posted
• Preoperative Anti-PD-1 Antibody Combined With Chemoradiotherapy for Locally Advanced Squamous Cell Carcinoma of EsophagusCompletedNCT03792347Phase 1Results posted
• Cetuximab in Head and Neck Cancer PatientsCompletedNCT03769311Phase 2Results posted
• Temporally Feathered Radiation Therapy (TFRT) for Head and Neck Squamous Cell CarcinomaCompletedNCT03768856Not applicableResults posted
• REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)CompletedNCT03721978Phase 3Results posted
• Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx CancerCompletedNCT03715946Phase 2Results posted
• Study of TVEC in Patients With Cutaneous Squamous Cell CancerCompletedNCT03714828Phase 2Results posted
• Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility TrialCompletedNCT03690921Phase 2Results posted
• Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based ChemotherapyTerminatedNCT03655444Phase 1/2Results posted
• Alpelisib in Treating Participants With Transorally Resectable HPV-Associated Stage I-IVA Oropharyngeal CancerTerminatedNCT03601507Phase 2Results posted
• Durvalumab, Tremelimumab and Hypofractionated Radiation Therapy in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT03522584Phase 1/2Results posted
• Intensity-Modulated Radiation Therapy & Nivolumab for Recurrent or Second Primary Head & Neck Squamous Cell CancerCompletedNCT03521570Phase 2Results posted
• Using MC1R Genotype to Impact Melanoma Risk BehaviorCompletedNCT03509467Not applicableResults posted
• Safety and Efficacy Study of PRV111 in Subjects With Oral Squamous Cell CarcinomaCompletedNCT03502148Phase 1/2Results posted
• VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2CompletedNCT03499795Phase 2Results posted
• Quercetin Chemoprevention for Squamous Cell Carcinoma in Patients With Fanconi AnemiaCompletedNCT03476330Phase 2Results posted
• A Study of Atezolizumab (Anti-PD-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and NeckTerminatedNCT03452137Phase 3Results posted
• A Study of Tislelizumab (BGB-A317) Versus Chemotherapy as Second Line Treatment in Participants With Advanced Esophageal Squamous Cell CarcinomaCompletedNCT03430843Phase 3Results posted
• Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell CarcinomaCompletedNCT03422536Phase 2Results posted
• Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck CancerCompletedNCT03405142Phase 2Results posted
• QUILT-3.090: NANT Squamous Cell Carcinoma (SCC) Vaccine: Subjects With SCC Who Have ProgressedTerminatedNCT03387111Phase 1/2Results posted
• Nivolumab or Nivolumab Plus Cisplatin, in Combination With Radiotherapy in Patients With Cisplatin-ineligible or Eligible Locally Advanced Squamous Cell Head and Neck CancerCompletedNCT03349710Phase 3Results posted
• Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by SurgeryCompletedNCT03342911Phase 2Results posted
• Neodjuvant Nivolumab and Lirilumab, Followed by Surgery, Followed by Adjuvant Nivolumab and Lirilumab, in SCCHNActive, not recruitingNCT03341936Phase 2Results posted
• Study of Pembrolizumab (MK-3475) in Adults With Recurrent/Metastatic Cutaneous Squamous Cell Carcinoma (cSCC) or Locally Advanced Unresectable cSCC (MK-3475-629/KEYNOTE-629)CompletedNCT03284424Phase 2Results posted
• Immune Checkpoint Therapy With Nivolumab Esophageal Squamous Cell CarcinomaTerminatedNCT03278626Phase 1/2Results posted
• A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell CarcinomaTerminatedNCT03254927Phase 2Results posted
• DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck CancerCompletedNCT03237325Phase 3Results posted
• Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or LymphomaCompletedNCT03229278Phase 1Results posted
• Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision TherapyTerminatedNCT03223662Phase 2Results posted
• Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial LesionsTerminatedNCT03197025Phase 1Results posted
• Phase II Trial Evaluating the Efficacy of Palbociclib in Combination With Carboplatin for the Treatment of Unresectable Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaCompletedNCT03194373Phase 2Results posted
• REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)CompletedNCT03185013Phase 3Results posted
• Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)CompletedNCT03180684Phase 2Results posted
• Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell CarcinomaActive, not recruitingNCT03174275Phase 2Results posted
• Testing Afatinib in Combination With Pembrolizumab in Patients With Squamous Cell Carcinoma of the LungCompletedNCT03157089Phase 2Results posted
• Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line TreatmentCompletedNCT03116152Phase 2Results posted
• A Trial to Compare the Incidence of Squamous Cell Carcinoma (SCC) and Other Skin Neoplasia on Skin Areas Treated With Ingenol Disoxate Gel or Vehicle Gel for Actinic Keratosis on Face and Chest or ScalpTerminatedNCT03115476Phase 3Results posted
• Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare TumorsCompletedNCT03108131Phase 2Results posted
• Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck CancerCompletedNCT03107182Phase 2Results posted
• Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity CancerTerminatedNCT03090412Phase 2Results posted
• Study of LN-145/LN-145-S1 Autologous Tumor Infiltrating Lymphocytes in the Treatment of Squamous Cell Carcinoma of the Head & NeckCompletedNCT03083873Phase 2Results posted
• P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCCCompletedNCT03077243Phase 2Results posted
• Involved Field Elective Volume De-Intensification Radiation Therapy for Head and Neck CancerCompletedNCT03067610Phase 2Results posted
• The Addition of Pembrolizumab to Postoperative Radiotherapy in Cutaneous Squamous Cell Cancer of the Head and NeckCompletedNCT03057613Phase 2Results posted
• Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck CancerCompletedNCT03032250Not applicableResults posted

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