Bone Neoplasms clinical trials

The registry lists 320 studies for Bone Neoplasms across more than 10 countries. 80 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-21.

Studies

Recruiting first, then most recently updated. Showing 50 of 320 — search for more.

• Financial Toxicity in Patients With Resected Soft Tissue and Bone SarcomasRecruitingNCT072156111 country
• Registry of Minimally Invasive Cancer Treatment Using Spectral Angio-CT Image GuidanceRecruitingNCT076361482 countries
• Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting SarcomasNot yet recruitingNCT03356782Phase 1/21 country
• Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot InterventionRecruitingNCT07662239Not applicable1 country
• Combination Immunotherapy Targeting SarcomasNot yet recruitingNCT04433221Phase 1/21 country
• Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal MetastasesRecruitingNCT03965234Phase 1/21 country
• Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's LymphomaRecruitingNCT07514819Not applicable1 country
• Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With SarcomaRecruitingNCT064090131 country
• "Exercise Intervention to Increase Physical Activity in Young Sarcoma Survivors (Sport Ist Herzenssache)"Not yet recruitingNCT07729059Not applicable
• Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue CancerRecruitingNCT077274341 country
• U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK ProceduresRecruitingNCT07325578Not applicable1 country
• Intraoperative Neuromonitoring of Sacral Reflexes to Predict Post Operative Function in Patients Undergoing Sacrectomy for Pelvic Bone Malignancy or Patients Undergoing Spinal Procedures Without Sacral Root InvolvementNot yet recruitingNCT07707024Not applicable1 country
• Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary MetastasesRecruitingNCT03093909Phase 11 country
• The Effect of Acute Normovolemic Hemodilution in Bone Tumor SurgeryRecruitingNCT06459141Not applicable1 country
• A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)RecruitingNCT07193550Phase 21 country
• XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue SarcomaRecruitingNCT06571734Phase 21 country
• EVERolimus and LenvAtinib Versus Everolimus for Bone SarcomaNot yet recruitingNCT07619950Phase 2
• Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone MetasRecruitingNCT05419518Phase 21 country
• Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing SarcomaNot yet recruitingNCT076204311 country
• Preoperative Immunonutrition in Patients With Bone and Soft Tissue SarcomasRecruitingNCT07609329Not applicable1 country
• Proximal Femur Reconstruction Following Resection of Primary Bone Tumors: Analysis of the Clinical and Radiographic ResultsRecruitingNCT064865061 country
• Iscador® P (Mistletoe) Immunotherapy for Recurrent Resectable Osteogenic SarcomaRecruitingNCT05726383Phase 21 country
• Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With SarcomaRecruitingNCT06129903Not applicable1 country
• Samarium Optimized for Long-lasting Analgesia in Cancerous End-stage Bone PainRecruitingNCT07197645Phase 11 country
• Treatment of Truncated ALK-positive Bone Cancer Using Crizotinib (Xalkori) or Alectinib (Alecensa)Not yet recruitingNCT07560410Phase 1/21 country
• Mg OSTEOCRETE Post-Treatment OutcomesRecruitingNCT067201421 country
• Assessment of Healing and Function After Reconstruction Surgery for Bone SarcomasRecruitingNCT034424651 country
• Assessment of the Functional Outcome and Quality of Life in Sarcoma PatientsRecruitingNCT05051059Not applicable1 country
• Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the BoneRecruitingNCT050332881 country
• Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone SarcomasRecruitingNCT04055220Not applicable1 country
• Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas PatientsRecruitingNCT04698785Phase 21 country
• An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor RegistryRecruitingNCT026779611 country
• Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage SurgeryRecruitingNCT057796701 country
• Evaluation of Tumor Resection and Reconstruction With Prosthetic ImplantsNot yet recruitingNCT07337018
• The Effect of Preoperative Intravenous Ferric Derisomaltose and EPO and Tranexamic Acid in Patients With Preoperative Anemia or Iron Deficiency in Bone TumorNot yet recruitingNCT07314424Phase 4
• In Vivo Lung Perfusion for Pulmonary Metastases of SarcomaRecruitingNCT02811523Phase 11 country
• Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated ConditionsRecruitingNCT031602741 country
• LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic OncologyEnrolling by invitationNCT03244020Phase 41 country
• Efficacy of Pre-operative Prehabilitation in Patients With Limb SarcomaRecruitingNCT04515459Phase 21 country
• Radiotherapy Treatments for Neoplasms of the LimbsRecruitingNCT063352511 country
• Stereotactic Multiple Fraction Radiotherapy for Non-spine Bone MetastasesRecruitingNCT05406063Not applicable1 country
• Investigation Into the Safety and Efficacy of ICG-Labeled Fluorescence Imaging Technology in Guiding the Resection of Bone and Soft Tissue TumorsNot yet recruitingNCT069791151 country
• Definitive Radiation for High-Risk Spine MetastasesRecruitingNCT06165419Phase 21 country
• Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone TumorsRecruitingNCT069358641 country
• A Substudy of the Effect of Acute Normovolemic Hemodilution in Bone Tumor SurgeryRecruitingNCT06881498Not applicable1 country
• Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone MetastasesRecruitingNCT06069570Phase 11 country
• Biomolecular Markers of Bone MetastasisRecruitingNCT06806462Not applicable1 country
• Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal TumorRecruitingNCT067747291 country
• Tislelizumab Combined with Nab-Paclitaxel for First-Line Treatment of Advanced Triple-Negative Breast Cancer with Bone Metastasis，an Exploratory, Single-Arm, Multicenter Phase II Clinical StudyRecruitingNCT06538896Phase 21 country
• Efficacy of ICG-based NIR Imaging in Intralesional Curettage of Giant Cell Tumors of Bone in Limbs: a Prospective, Single-center, Single-arm, Open StudyRecruitingNCT06647901Phase 1/21 country