Bile Duct Diseases clinical trials
The registry lists 50 studies for Bile Duct Diseases across more than 10 countries. 13 are recruiting or about to start. 17 of them are mainly about Bile Duct Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-20. Counting its 12 narrower conditions too, such as Bile Duct Neoplasms: 1,049 studies, 227 open.
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Who runs them
Mirum Pharmaceuticals, Inc. (7) · Changhai Hospital (3) · RenJi Hospital (2) · Boston Scientific Corporation (2) · Methodist Health System (2) · University of Virginia (1) · Asan Medical Center (1) · Merck Sharp & Dohme LLC (1)
What is being tested here
Drugs under test in Bile Duct Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Upadacitinib | 1 | 0 | 1 |
| Maralixibat | 0 | 2 | 6 |
| Regorafenib | 0 | 0 | 1 |
| Seladelpar | 0 | 0 | 1 |
| Pinaverium | 0 | 0 | 1 |
| Berberine ursodeoxycholate | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026Outcomes From Treatment Liver and Bile Duct Diseases · Methodist Health System
- Dec 2026Endoscopic Ultrasound-guided Rendezvous Versus Precut Papillotomy · Chinese University of Hong Kong
- Dec 2026Gut Microbiome and Metabolome in Patients With Gallstone Disease After Surgical and Endoscopic Interventions · Changi General Hospital
- Jul 2027Biochemical Response and Clinical Outcomes in Patients With PBC · RenJi Hospital
- Nov 2027The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe Itching · RenJi Hospital
Who these studies take
Of the 9 Bile Duct Diseases studies recruiting now, 2 (22%) set no upper age limit and 0 (0%) stop at 75 or younger. 2 (22%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 8 (89%) | 8 (89%) |
| 30 | 9 (100%) | 9 (100%) |
| 40 | 9 (100%) | 9 (100%) |
| 50 | 9 (100%) | 9 (100%) |
| 65 | 9 (100%) | 9 (100%) |
| 75 | 9 (100%) | 9 (100%) |
| 85 | 6 (67%) | 6 (67%) |
Across all 50 studies, recruiting or not: 18% stop at 75 or younger and 12% at 65; 22% take children; 0% are for women only and 0% for men only; 10% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 50. search them.
- EUS Examination Using EndoSound Vision System vs. Standard EchoendoscopeRecruitingNCT06340620Not applicable1 country
- Endoscopic Ultrasound-guided Rendezvous Versus Precut PapillotomyRecruitingNCT06010576Not applicable1 country
- The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe ItchingNot yet recruitingNCT07678645Phase 21 country
- UNITY-B A Prospective, Multicentric, Single-arm Study to Evaluate the Safety and Efficacy of the UNITY-B Biodegradable Balloon-Expandable Biliary Stent System in Subjects With Biliary StricturesRecruitingNCT04929821Not applicable3 countries
- Gut Microbiome and Metabolome in Patients With Gallstone Disease After Surgical and Endoscopic InterventionsRecruitingNCT056892551 country
- Biochemical Response and Clinical Outcomes in Patients With PBCRecruitingNCT074497931 country
- Time to Post-operative Recovery of Serum Albumin as a Predictor of Outcome in Major Hepato Pancreato Biliary SurgeriesRecruitingNCT072630611 country
- Flare Type Self-expandable Metal Stents (SEMS) vs Plastic Stent for the Treatment of Difficult Common Bile Duct StoneNot yet recruitingNCT06170632Not applicable1 country
- A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation ProfilesRecruitingNCT061156551 country
- Endoscopic Scissors Cutting Nasobiliary Duct VS Bilateral Plastic StentRecruitingNCT06106750Not applicable1 country
- Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry StudyEnrolling by invitationNCT050513581 country
- The Role of Endoscopic Ultrasound in Evaluation of Patients With Indefinite Cause of Bile Duct DilatationNot yet recruitingNCT05475964Not applicable1 country
- Results of Surgical Treatment of the Hepatobiliopancreatic Surgical UnitRecruitingNCT045560191 country
- A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)WithdrawnNCT03678480Phase 2
- An Extension Study of Maralixibat in Patients With Progressive Familial Intrahepatic Cholestasis (PFIC)CompletedNCT04185363Phase 316 countries
- Outcomes From Treatment Liver and Bile Duct DiseasesActive, not recruitingNCT046372431 country
- A Study to Evaluate the Safety and Tolerability of Maralixibat in Infant Participants With Cholestatic Liver Diseases Including Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille Syndrome (ALGS).CompletedNCT04729751Phase 27 countries
- AE05ML Device for ML Hem-o-lok Polymer Clip Delivery in Laparoscopic Surgical Procedures Observational Registery StudyCompletedNCT063648651 country
- Patient Reported Experience in Endoscopic UltrasoundActive, not recruitingNCT050143471 country
- Evaluation of Safety and Efficacy of NvisionVLE® Imaging Low Profile System in Patients With Bile Duct DiseaseCompletedNCT052637521 country
- Role of Prophylactic Aggressive Hydration to Prevent Post-ERCP PancreatitisCompletedNCT07417020Not applicable1 country
- MRX-800: A Long-Term Safety Study of Maralixibat in the Treatment of Cholestatic Liver Disease in Subjects Who Previously Participated in a Maralixibat StudyCompletedNCT04168385Phase 28 countries
- Evaluation of Maralixibat in Biliary Atresia Response Post-KasaiCompletedNCT04524390Phase 28 countries
- A Study to Evaluate the Safety, and Tolerability, and Efficacy of Seladelpar in Patients With PSCTerminatedNCT04024813Phase 23 countries
- SpyGlass Surgical StudyCompletedNCT058226354 countries
- Angled-tip vs. Straight-tip Guidewire in Biliary CannulationCompletedNCT05600270Not applicable1 country
- Cholangiography Using Carbon Dioxide Versus Iodinated Contrast in ERCPActive, not recruitingNCT02611453Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of Maralixibat in Subjects With Progressive Familial Intrahepatic Cholestasis (MARCH-PFIC)CompletedNCT03905330Phase 317 countries
- SpyGlass™ Discover PercutaneousCompletedNCT045809407 countries
- Open Label Study to Evaluate Efficacy and Long Term Safety of LUM001 (Maralixibat) in the Treatment of Cholestatic Liver Disease in Patients With Progressive Familial Intrahepatic CholestasisCompletedNCT02057718Phase 24 countries
- Treatment Outcomes in Bile Duct StonesCompletedNCT041458431 country
- Validation of an AI-based Biliopancreatic EUS Navigation System for Real-time Quality Improvement: A Prospective, Single-center, Randomized Controlled TrialStatus unknownNCT05457101Not applicable1 country
- Infection Control in ERCP Using a Duodenoscope With a Disposable CapCompletedNCT04040504Not applicable1 country
- Trainee Involvement in ERCP Risk ScoreCompletedNCT043419091 country
- A Maralixibat Expanded Access Program for Patients With Cholestatic Pruritus Associated With Alagille Syndrome (ALGS)Approved for marketingNCT045309941 country
- Single Agent Regorafenib in Refractory Advanced Biliary CancersCompletedNCT02115542Phase 21 country
- Feasibility of Laryngeal Mask Airway Gastro on Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Pancreas and Bile Duct DisordersCompletedNCT03775681Not applicable1 country
- Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China HospitalCompletedNCT029174081 country
- Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management StudyStatus unknownNCT039513241 country
- Impact of Pinaverium Bromide on Bile Duct and Pancreatic Duct Cannulation During Endoscopic Retrograde CholangiopancreatographyStatus unknownNCT02882451Not applicable1 country
- Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal DisordersStatus unknownNCT014383851 country
- Multibending vs Conventional Endoscope for Direct Peroral CholangioscopyStatus unknownNCT02189421Not applicable1 country
- Safety and Efficacy Study of IL-10 (Tenovil TM) in the Prevention of Post-ERCP Acute Pancreatitis (Study P02580)(TERMINATED)TerminatedNCT00040131Phase 2
- Intra-ductal Confocal Endomicroscopy for Characterization of Pancreas and Bile Duct TumorCompletedNCT00930410Not applicable2 countries
- Comparison of Endoscopic Radiofrequency Ablation Versus Photodynamic Therapy for Inoperable CholangiocarcinomaStatus unknownNCT01739465Phase 2/31 country
- Compare the Knob-tipped Knife With the Needle Knife in Difficult Biliary CannulationStatus unknownNCT01745978Phase 31 country
- Safety and Efficacy of a Newly Developed Baby-sphincterotome for Bile Duct CannulationCompletedNCT01493076
- Newly Designed Fully Covered Metal Stent for the Benign Biliary StrictureCompletedNCT00945516Phase 31 country
- Drotaverine Hydrochloride Versus Hyoscine-N-butylbromide for Duodenal Antimotility During Endoscopic Retrograde Cholangiopancreatography (ERCP)CompletedNCT00731198Phase 31 country
- Efficacy of Double Wire Technique in Difficult Cases of Common Bile Duct Cannulation in ERCP (UDOGUIA-04)Status unknownNCT00270868Not applicable1 country