An observational study in Hepatobiliary Disease, Pancreas Disease and Bile Duct Diseases, sponsored by Institute of Liver and Biliary Sciences, India. Recruiting at 1 site in India. Open to participants aged 13 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-12-31.
Sponsored by Institute of Liver and Biliary Sciences, India · Observational
Hepatobiliary and Pancreatic surgery is associated with substantial risk of postoperative complications. Albumin is a negative acute phase protein. Its rapid decline may be due to degree of inflammation due to surgical procedures. The decline may due to multifactorial causes. Currently, contemporary data regarding the time to recovery of albumin, as a marker for early recovery of patient from surgical stress is sparse. Delta albumin is influenced by perioperative fluid administration and albumin supplementation. Delta albumin may not reflect the true surgical stress. Early post op albumin is a reflection of intraoperative events and not postoperative recovery or events and is unpredictable. Shorter recovery time of albumin is associated with less post op complications and hospital stay. Earlier recovery of albumin predicts lower morbidity and shorter hospital stay.
Hepatobiliary and Pancreatic surgery is associated with substantial risk of postoperative complications. Albumin is a negative acute phase protein. Its rapid decline may be due to degree of inflammation due to surgical procedures. The decline may due to multifactorial causes. Currently, contemporary data regarding the time to recovery of albumin, as a marker for early recovery of patient from surgical stress is sparse. Delta albumin is influenced by perioperative fluid administration and albumin supplementation. Delta albumin may not reflect the true surgical stress.
613 studies on the registry are indexed under Digestive System Diseases; 117 are open to participants now.
This study's planned enrollment of 1,000 is above the median of 272 across 193 observational studies indexed under Digestive System Diseases.
Browse Digestive System Diseases studies →Institute of Liver and Biliary Sciences, India is the lead sponsor of 296 studies on the registry; 84 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients undergoing major Hepato pancreatico Biliary surgeries.
Exclusion Criteria:
Patients undergoing Major Hepato Pancreato biliary surgeries
Other: NO TREATMENT
NO TREATMENT
Time to recovery of serum albumin as a predictor of outcome in major hepatobiliary surgeries as measured by hospital stay.
Time taken for unsupported albumin in Liver function test in a rising trend (g/dl)
Time frame: 30 days
To correlate the time to recovery of albumin with complications and morbidity (Clavien Dindo classification, Comprehensive Complication Index, Intensive Care Unit Stay)
Major Complications measured by Clavien Dindo Classification (Major \>grade 3A) and Comprehensive complication index (Major More than 27)
Time frame: 30 days
Time to reversal trend of albumin and Hospital stay
Time taken for unsupported albumin in Liver function test to reach a value of more than 3 g/dl and compared with the hospital stay
Time frame: 30 days
correlation of time to recovery of albumin and re admission rates
Time taken for unsupported albumin in Liver function test to reach a value of more than 3 g/dl and compared with the 90 day re admission rates
Time frame: 90 days
Plan to share: Undecided
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Institute of Liver and Biliary Sciences, India