An interventional study of Collection of biological sample with sera, CSF, buffy coat, PBMC, plasma. in Paraneoplastic Neurological Syndromes or Autoimmune Encephalitis, sponsored by Hospices Civils de Lyon. Recruiting at 62 sites in France. Per ClinicalTrials.gov, last updated 2024-02-29.
Sponsored by Hospices Civils de Lyon · Not applicable, Interventional, and Other
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Among 22 studies in Autoimmune Diseases of the Nervous System by Hospices Civils de Lyon — 8 open to participants now, 11 under way, none of them phase 3. Autoimmune Diseases of the Nervous System · Hospices Civils de Lyon.
Among the 22 studies in Autoimmune Diseases of the Nervous System by Hospices Civils de Lyon, this one is one of 5 that started in 2022, is the only one with no phase, reaches primary completion later than 10 of the 10 other live ones, and was the 8th registered.
123 studies on the registry are indexed under Autoimmune Diseases of the Nervous System; 59 are open to participants now.
Browse Autoimmune Diseases of the Nervous System studies →8 of the 22 studies in Autoimmune Diseases of the Nervous System by Hospices Civils de Lyon are open now, in 1 country. Recruiting first, the newest first:
Hospices Civils de Lyon · Sites in France
Ages 18+
Hospices Civils de Lyon · Sites in France
Hospices Civils de Lyon · Sites in France
Ages 18–100
Hospices Civils de Lyon · Sites in France
Ages 18+
Hospices Civils de Lyon · Sites in France
Ages 18+
By country, each count listing its studies:
Of the 44 Autoimmune Diseases of the Nervous System studies recruiting now, 27 (61%) set no upper age limit and 11 (25%) stop at 75 or younger; 15 take children under 18; 9 take healthy volunteers.
This study: all sexes · no healthy volunteers.
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22 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 5 started in 2022.
This study's planned enrollment of 3,500 is above the median of 40 across 63 interventional studies indexed under Autoimmune Diseases of the Nervous System.
Median enrollment 3,500 across the 1 interventional studies, 50 across the 21 observational. Of the 8 that completed or were terminated, 0 (0%) have results posted.
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Hospices Civils de Lyon is the lead sponsor of 1,867 studies on the registry; 448 are open to participants now.
1 of the studies in Autoimmune Diseases of the Nervous System by Hospices Civils de Lyon that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07158229Hospices Civils de LyonLong-term Impact of NMDAR Encephalitis, Level 3 | 2026-11-21 |
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Among the 22 studies in Autoimmune Diseases of the Nervous System by Hospices Civils de Lyon, from their registry updates:
Nothing recorded among them since 2026-09-25.
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Numerous neurological disorders affecting the central and peripheral nervous system can be attributed to the immune system through multiple effector mechanisms. However, current treatments could be drastically improved by faster and more accurate diagnosis. The sample collection will benefit to patients with rare neuroimmune syndromes such as Autoimmune Encephalitis (AE) and Paraneoplastic Neurological Syndromes (PNS) leading to a better and early diagnosis, as well as treatment improvement.
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Exclusion Criteria:
patients with diagnosis of paraneoplastic neurological syndrome or autoimmune encephalitis
Biological: Collection of biological sample with sera, CSF, buffy coat, PBMC, plasma.
Blood is collected only one time by blood sample to obtain serum, buffy coat, plasma and PBMC. 2 \*4ml of blood on dry tube 2 \*4ml of blood on EDTA tube If possibility of delivery in 48 hours at the Centre of Biological Resources, 7\*4ml of blood on heparin tube If cerebrospinal fluid has been drawn for diagnosis, remaining sample available will be stored in the collection
Blood Samples
Assessment of biocollection of blood samples
Time frame: 10 years
Cerebrospinal fluid biocollection
Assessment of biocollection of Cerebrospinal fluid
Time frame: 10 years
Scientific collaboration
Number of project issued from the biocollection
Time frame: 10 years
Scientific
Number of scientific papers issued from the biocollection
Time frame: 10 years
Plan to share: Undecided
No publications or documents are linked to this record.
Started Aug 2022 (actual). Primary completion is estimated for Aug 2032, 120 months after the start.
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Autoimmune Diseases of the Nervous System →