Acute Lung Injury: all 994 studies

Page 1 of 10. Open to participants first (156), then studies with results posted, then the rest; newest registration first within each.

• The Effect of Catheter Size on the Efficacy of Ultralow-flow Extracorporeal Carbon Dioxide Removal System in Acute Respiratory Distress SyndromeNot yet recruitingNCT07858136Not applicable
• Assessment of Blood Viscosity in ARDS (Acute Respiratory Distress Syndrome)Not yet recruitingNCT07823296
• The Variable Ventilation Trial (Part A)Not yet recruitingNCT07791225Not applicable
• Trial of Total Lung Protective Ventilation in Adult VV-ECMO Patients With Severe ARDSNot yet recruitingNCT07790133Not applicable
• Precision Medicine Adaptive Network Platform Trial in Hypoxemic Acute Respiratory FailureNot yet recruitingNCT07779642Phase 2
• Safety and Efficacy Study of GKL-006RTU in Moderate to Severe Acute Respiratory Distress Syndrome (ARDS)Not yet recruitingNCT07706855Phase 1/2
• Outer Membrane Vesicle and Ferroptosis-Related Signatures in Sepsis-Associated Acute Lung Injury Caused by Extra-Pulmonary Hypervirulent Klebsiella PneumoniaeNot yet recruitingNCT07686887
• Time-controlled Adaptive Ventilation (TCAV) Compared With Conventional Ventilation in Patients With Moderate-to-severe Acute Respiratory Distress Syndrome (ARDS) Secondary to Community-acquired PneumoniaNot yet recruitingNCT07679802Not applicable
• Observational, Non-interventional Biomarker and Endotyping StudyRecruitingNCT07675265
• Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological DistressNot yet recruitingNCT07634419Not applicable
• BALance: ARDS Deconvolution by Bronchoalveolar Lavage Multiomics and RadiomicsRecruitingNCT07633366
• Titration of Positive End-expiratory Pressure: Comparison Between Manual Thoracic or Abdominal Compression and Electrical Impedance TomographyRecruitingNCT07623590Not applicable
• EIT Evaluation of the Impact of Inhaled Nitric Oxide on Ventilation/Perfusion Mismatch in ARDS Patients Receiving Noninvasive Respiratory SupportNot yet recruitingNCT07617298
• Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT ImagingRecruitingNCT07613099Phase 3
• Influence of Lung Recruitment Potential on Positive End-Expiratory Pressure (PEEP) Titration Strategies in Acute Respiratory Distress Syndrome (ARDS) Patients.RecruitingNCT07603310Not applicable
• Ondansetron for the Prevention of Patient Self-Inflicted Lung Injury in Patients With ARDS - Pilot RCTNot yet recruitingNCT07588217Phase 2/3
• SWedish Intensive Care BiobankNot yet recruitingNCT07582601
• Continuous vs Bolus Neuromuscular Blockade Regimens in Moderate to Severe Hypoxemic Respiratory Failure and ARDS (COBRA)Not yet recruitingNCT07567768Phase 2
• A Single Dose, Dose Escalation Clinical Trial on the Safety, Tolerability and Efficacy of Lyophilized Powder for Inhalation of Recombinant Human Keratinocyte Growth Factor-2 (Rh-KGF-2) in The Treatment of Patients With Acute Respiratory Distress SyndromeRecruitingNCT07558538Early Phase 1
• Perioperative Lidocaine for Lung Protection in Infants Undergoing Cardiac SurgeryNot yet recruitingNCT07499154Phase 4
• The Impact of Automatic Lung Recruitment Postoperative Pulmonary ComplicationsNot yet recruitingNCT07477951Not applicable
• Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 for Treating ARDSRecruitingNCT07449572Phase 1
• Comparative Analysis of Salivary and Bronchoalveolar Lavage IL-6 and TNF-α as Biomarkers in Pediatric Acute Respiratory Distress SyndromeEnrolling by invitationNCT07380373
• The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in MartiniqueNot yet recruitingNCT07351435
• A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota TransplantationRecruitingNCT07342205Phase 2/3
• Cyclic On-off Switching of Pulmonary Blood Flow in Moderate to Severe ARDSNot yet recruitingNCT07327268
• Lung EIT Image Guide Ventilation in ARDSRecruitingNCT07309783Not applicable
• Real-Time Algorithm-Driven Ventilation Feedback to Improve Lung-Protective Ventilation in Patients With ARDS (REALVENT-study)RecruitingNCT07307066Not applicable
• EARLY-SARDS: Early AlveolaR Lung biologY Underling Sepsis-Associated ARDSNot yet recruitingNCT07281911
• Recovery of Physical Function After Critical Illness In Older AdultsRecruitingNCT07225257
• The Impact of Low Versus High Positive End-expiratory Pressure on Diaphragm Function, Ventilation Efficiency, and Lung MechanicsRecruitingNCT07188038Not applicable
• A Real World Study of Respiratory Critical Disease.RecruitingNCT07165717
• Safety and Performance of the Novalung Ultimate Kit and Xenios 2.0 During Stationary Use in Hospital and Ground-based Transport of Patients on Extracorporeal Life Support (ECLS)RecruitingNCT07156669
• Assessment of Acute Respiratory Distress in Children Presenting to the Emergency Department: Clinical, Epidemiological, and Etiological InsightsNot yet recruitingNCT07149389
• Lung Injury is One of the Primary Causes of Morbidity and Mortality in Critically Ill Patients. These Patients Will be Monitored for: 1) Immune Cell Activation 2) Blood-based Biomarkers. In Vitro Models Derived From These Samples Will be Treated With Novel Agent PIP-2 to Evaluate Its Efficacy.RecruitingNCT07125079
• The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic SurgeryRecruitingNCT07100860
• Prone Position Assessed by 3D EITRecruitingNCT07083973
• Digital Early Warning System for Acute Lung Injury in Liver SurgeryRecruitingNCT07070362
• Effect of EIT-guided PEEP in ARDS PatientsRecruitingNCT06990477Not applicable
• Electrical Impedance Tomography-Based Prognostic Model for ARDSRecruitingNCT06967207
• Safety and Efficacy of Low-Flow ECMO in a Multi-modal Cohort of Adults in Respiratory FailureEnrolling by invitationNCT06938217Not applicable
• EIT-Guided Ventilator Settings in AHRFRecruitingNCT06936618Not applicable
• Ciprofol's Impact on Oxygenator Function in Extracorporeal Membrane Oxygenation (ECMO) PatientsNot yet recruitingNCT06934811Phase 4
• Pleural Strain by Speckle-Tracking Ultrasound: Feasibility and Driving Pressure AssociationsRecruitingNCT06911450
• Role of Elastic Power in Acute Respiratory Distress SyndromeNot yet recruitingNCT06878313
• Free for Weaning ECMO vs Respiratory Driven StudyRecruitingNCT06876415Not applicable
• This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft DysfunctionRecruitingNCT06853223Phase 2
• Prevention of Lung Injury Induced by Mechanical Ventilation in Acute Respiratory Distress Syndrome ARDS PatientsNot yet recruitingNCT06835881
• By Assessing the Continuous Respiratory Physiological Changes Through Prone Position, Determine the Optimal Duration for Prone PositionRecruitingNCT06827184
• VExUS in Ards Patients and Association with AKIRecruitingNCT06805409
• Effects of Low Tidal Volume and Airway Pressure Release Ventilation on Lung Tissue Mechanics in ARDS Patients Under Mechanical Ventilation: A Prospective Randomized Crossover StudyRecruitingNCT06790875Not applicable
• SerpinB3 Expression, PAR2 and SCCA-PD Polymorphism in Acute Respiratory Distress SyndromeRecruitingNCT06774534
• Compare Between APRV and Bipap Ventilation in ARDS PatientsNot yet recruitingNCT06755320Not applicable
• Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac FailureRecruitingNCT06750536
• EXTEND ARDS-J Esophageal Pressure StudyRecruitingNCT06734988
• Mucosal Associated Invariant T Cell During Viral Pneumonia and Acute Respiratory Distress SyndromeRecruitingNCT06720818
• CUrrent Practices of Intensive Care for the Management of Acute Respiratory Distress Syndrome in EurOpe.Not yet recruitingNCT06714201
• JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)RecruitingNCT06703073Phase 2
• JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: VilobelimabRecruitingNCT06701682Phase 2
• JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: ParidiprubartRecruitingNCT06701669Phase 2
• JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: BevacizumabRecruitingNCT06701656Phase 2
• Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDSRecruitingNCT06696638Not applicable
• Physiologic Effects of Continuous Positive Airway Pressure and High Flow Nasal Oxygenation in Patients with Acute Respiratory Distress Syndrome.RecruitingNCT06694311Not applicable
• Effects of End-inspiratory Pause on VentilationNot yet recruitingNCT06692634Not applicable
• Dead Space and Inhaled Nitric Oxide in Pediatric Acute Respiratory Distress SyndromeRecruitingNCT06690801
• Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)RecruitingNCT06684119Not applicable
• Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in Mechanical Ventilation PatientsRecruitingNCT06662630Not applicable
• ALI & Pulmonary HA Deposition After SAHRecruitingNCT06628531
• International Survey for EXTubation Evaluation and Respiratory Dynamics in Acute Respiratory Distress SyndromeEnrolling by invitationNCT06598709
• Physiological Studies in the Prone Position in Patients With ARDSRecruitingNCT06586736
• RECOMMEND Platform TrialRecruitingNCT06526533Phase 3
• Effect of Different Depths of Neuromuscular Blockade on Respiratory Mechanics in Patients With Moderate-severe Acute Respiratory Distress SyndromeRecruitingNCT06514209Not applicable
• Anti-CD14 Treatment With IC14 in Hospitalized ARDS PatientsRecruitingNCT06513949Phase 2
• Clinical Study on the Safety and Preliminary Efficacy of hUC-MSCs Intravenous Infusion Therapy for ARDSNot yet recruitingNCT06505941Phase 1/2
• High Flow Nasal Oxygen for Acute Hypoxemic Respiratory Failure in the Emergency RoomNot yet recruitingNCT06489379Not applicable
• The Role of Elastic Power in Predicting the Severity and Mortality in Adult Patients With ARDS Due to PneumoniaRecruitingNCT06477861
• Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant RecipientsRecruitingNCT06476132Phase 2
• Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDSRecruitingNCT06387823Not applicable
• Prone Position During ECMO in Pediatric Patients With Severe ARDSRecruitingNCT06369584Not applicable
• Closed-loop syncHronization vErsuS convenTional Synchronization in sPontaneously Breathing Adult Nonivasive ventilationPatientsRecruitingNCT06357780Not applicable
• Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress SyndromeNot yet recruitingNCT06322758Not applicable
• MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS PatientsNot yet recruitingNCT06308926Phase 2
• Assessment of Patient-ventilator Asynchrony by Electric Impedance TomographyNot yet recruitingNCT06290310
• Multiple Study of Electroaccpuncture in ARDSNot yet recruitingNCT06278675Not applicable
• The Role of Cxcr4Hi neutrOPhils in InflueNzaRecruitingNCT06254313
• Inhaled Nitric Oxide for ARDS-related Pulmonary HypertensionNot yet recruitingNCT06249633Early Phase 1
• Thorathic Fluid Content as an Early Predictor of Weaning From Mechanical Ventilation in Acute Respiratory Distress SyndromeRecruitingNCT06233448
• Effect of Nebulized and Intravenous Hypertonic Saline 3% on the Management of Patients With Acute Respiratory Distress SyndromeRecruitingNCT06226402Not applicable
• Effect of PP in Patients With Ultra-low VTRecruitingNCT06215209
• Effects on Biotrauma of NMBAs and PP Association During ARDSRecruitingNCT06212492Not applicable
• The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled TrialRecruitingNCT06203405Not applicable
• Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDSRecruitingNCT06188195Not applicable
• Prone Position With Different Types of Cushions in Patients With ARDSRecruitingNCT06184490Not applicable
• Lung Overdistension and Abdominal Pressure RiseRecruitingNCT06174636Not applicable
• Evaluation of VQm PHM on Pulmonary Health Parameters for ICUNot yet recruitingNCT06147674
• An Open-label Study of the Safety and Pharmacokinetics of the TGKPNot yet recruitingNCT06127381Phase 1
• ALI/ARDS Clinical Sub-phenotyping StudyRecruitingNCT06123962
• Combined Activity and Cognitive Intervention for ICU SurvivorsEnrolling by invitationNCT06117761Not applicable
• Quantitative Computed Tomography for Mortality Risk Stratification in ARDSRecruitingNCT06113276
• Longitudinal Recovery Trajectories After an Acute Respiratory Distress Syndrome, a New UnderstandingRecruitingNCT06083363

← Acute Lung Injury overview