An observational study in Any Condition Underlying Critical Illness, sponsored by Uppsala University. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-13.
Sponsored by Uppsala University · Observational
The goal of this observational study is to understand the genetic and molecular risk factors for developing critical illness in adult intensive care unit (ICU) patients in Sweden. The main questions it aims to answer are:
Which genetic variants are associated with increased risk of critical illness from conditions such as infections, sepsis, and organ failure?
Can circulating proteins and metabolites mediate the effect of genetic risk factors on the severity of illness?
Participants will:
Provide blood samples at ICU admission and again 3-6 months after discharge Consent to genetic analysis and data linkage with national health registries
Have their ICU treatment and outcomes followed using registry and clinical data
This study aims to build a national infrastructure for rapid sample collection and analysis that can also support research in future pandemics.
1,780 studies on the registry are indexed under Critical Illness; 442 are open to participants now.
This study's planned enrollment of 25,000 is above the median of 140 across 814 observational studies indexed under Critical Illness.
Browse Critical Illness studies →Uppsala University is the lead sponsor of 390 studies on the registry; 86 are open to participants now.
Compared within Critical Illness, the registry's first condition term, which may not be this study's main condition. Counted across the registry records on this site, refreshed daily. How we classify →
Any patient admitted to intensive care at a hospital in Sweden
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Any patient admitted to ICU in Sweden
30 day mortality
Death of any cause within 30 days of ICU admission
Time frame: 30 days
ICU admission
ICU admission for any specific cause
Time frame: 30 days
No study locations are listed for this record.
Plan to share: No — Swedish legal requirements preclude sharing individual patient data. Patient data access for collaborators is provided on a secure system.
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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