An interventional study of Acupuncture needles in Acute Respiratory Distress Syndrome and Sepsis, sponsored by Nanjing University of Traditional Chinese Medicine. Not yet recruiting at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-04-23.
Sponsored by Nanjing University of Traditional Chinese Medicine · Not applicable, Interventional, and Treatment
In order to clarify the clinical efficacy of electroacupuncture on inhibiting systemic inflammatory response, improving respiratory mechanics parameters and prognosis in patients with sepsis-related ARDS.
1,387 studies on the registry are indexed under Respiratory Distress Syndrome; 283 are open to participants now.
This study's planned enrollment of 264 is above the median of 60 across 822 interventional studies indexed under Respiratory Distress Syndrome.
Browse Respiratory Distress Syndrome studies →Nanjing University of Traditional Chinese Medicine is the lead sponsor of 17 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Experimental group: Sterile stainless steel needle electroacupuncture treatment was applied, and the acupuncture points were as follows: bilateral Zusanli (ST36), Neiguan (PC6), Hegu (LI4), Shaoshang (LU11), and Feng Long (ST40). 1 time a day, 30 minutes each time, for 7 days.
Device: Acupuncture needles
Control group: Placebo needles were applied, and the acupuncture points were as follows: bilateral Zusanli (ST36), Neiguan (PC6), Hegu (LI4), Shaoshang (LU11), and Feng Long (ST40). 1 time a day, 30 minutes each time, for 7 days.
1. Experimental group: Sterile stainless steel needle electroacupuncture treatment was applied, and the acupuncture points were as follows: bilateral Zusanli (ST36), Neiguan (PC6), Hegu (LI4), Shaoshang (LU11), and Feng Long (ST40). 1 time a day, 30 minutes each time, for 7 days. 2. Control group: Placebo needles were applied, and the acupuncture points were as follows: bilateral Zusanli (ST36), Neiguan (PC6), Hegu (LI4), Shaoshang (LU11), and Feng Long (ST40). 1 time a day, 30 minutes each time, for 7 days.
Respiratory mechanics indicators 1
Oxygenation index(P/F)
Time frame: Day 0、day 7
Respiratory mechanics indicators 2
Respiratory rate(RR)
Time frame: Day 0、day 7
Respiratory mechanics indicators 3
Driving pressure(DP)
Time frame: Day 0、day 7
Respiratory mechanics indicators 4
Positive end expiratory pressure(PEEP)
Time frame: Day 0、day 7
Respiratory mechanics indicators 5
Mechanical ventilation days(MV days)
Time frame: Day 0、day 7
Respiratory mechanics indicators 6
Mechanical ventilation free days(MV free days)
Time frame: Day 0、day 7
Respiratory mechanics indicators 7
Extubation situation
Time frame: Day 0、day 7
Sedation and analgesia
RASS score
Time frame: Day 0、day 7
Sedative drug use
The dose and duration of sedative medication will be recorded.
Time frame: Day 0、day 7
Analgesic drug use
The dose and duration of analgesic medication will be recorded.
Time frame: Day 0、day 7
Inflammatory factors
IL-1β、IL-6、IL-2、IL-4、IL-5、IL-8、IL-10、IL-17、IL-12、 IFN-γ、IFN-α、TNF-α.
Time frame: Day 0、day 7
CD4、CD8、CD4/CD8
Flow cytometry will be used to detect serum CD4, CD8 and CD4/CD8 levels.
Time frame: Day 0、day 7
Vasoactive drugs applications
The duration of vasoactive drug use will be recorded.
Time frame: Day 0 to day 7
CRRT applications
The duration of continuous renal replacement therapy will be recorded.
Time frame: Day 0 to day 7
ECMO applications
The duration of extracorporeal membrane oxygenation will be recorded.
Time frame: Day 0 to day 7
All-cause mortality to day 28
The prognosis of patients on the 28th days will be counted.
Time frame: Up to 28 days
All-cause mortality to day 60
The prognosis of patients on the 60th days will be counted.
Time frame: Up to 60 days
ICU-free days
The prognosis of patients ICU length of stay will be counted.
Time frame: 2 year
Hospital-free days
The prognosis of patients total length of stay will be counted.
Time frame: 2 year
Plan to share: No
No publications or documents are linked to this record.
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Respiratory Distress Syndrome →
Nanjing University of Traditional Chinese Medicine