ClinicalTrials.gg
CompletedNCT07770295Updated Aug 18, 2026

Effects of Foot Reflexology on Postoperative Pain, Anxiety, Nausea, and Vomiting Among Patients After Laparoscopic Cholecystectomy

An interventional study of Foot reflexology in Postoperative Pain, Anxiety and Nausea, sponsored by Ain Shams University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-08-18.

Sponsored by Ain Shams University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 9 months after the study started (first participant enrolled Oct 2024, registered Aug 2026).

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Phase
Not applicable
Study type
Interventional
Enrollment
108
Allocation
Non-randomized
Ages
18 Years to 60 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 102 studies in Pain, Postoperative by Ain Shams University — 24 open to participants now, 28 under way, 2 of them phase 3. Pain, Postoperative · Ain Shams University.

Enrollment
17th of 100
108 · median 60
Started
2024
with 18 others
No phase
62 of 102
15 open now
Registered
98th of 102
by date

Among the 102 studies in Pain, Postoperative by Ain Shams University, this one is the 17th largest by enrollment of the 100 interventional ones that give a count, is one of 19 that started in 2024, is one of 62 with no phase, and was the 98th registered.

Pain, Postoperative

5,644 studies on the registry are indexed under Pain, Postoperative; 1,229 are open to participants now.

Browse Pain, Postoperative studies →

Open to participants now

24 of the 102 studies in Pain, Postoperative by Ain Shams University are open now, in 1 country. Recruiting first, the newest first:

19 more — sign in →

By country, each count listing its studies:

All 24 open studies →

Where they have run

Who these studies take

Of the 678 Pain, Postoperative studies recruiting now, 241 (36%) set no upper age limit and 328 (48%) stop at 75 or younger; 74 take children under 18; 128 take healthy volunteers.

This study: 18 Years to 60 Years · all sexes · no healthy volunteers.

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02

Study summary

This study aims to evaluate the effect of foot reflexology on pain, anxiety, nausea, and vomiting among patients after laparoscopic cholecystectomy. Participants will receive foot reflexology in addition to routine postoperative care, and outcomes will be assessed using appropriate measures before and after the intervention.

Read the detailed description

Laparoscopic cholecystectomy is a commonly performed surgical procedure that may be associated with postoperative pain, anxiety, nausea, and vomiting. These symptoms can negatively affect patients' comfort and recovery. This study evaluates the effect of foot reflexology as a complementary nursing intervention on pain, anxiety, nausea, and vomiting among patients following laparoscopic cholecystectomy.

The study uses a quasi-experimental design. Eligible patients undergoing laparoscopic cholecystectomy will be recruited according to the predefined inclusion and exclusion criteria and allocated to the study and comparison groups according to the study protocol. The intervention group will receive foot reflexology in addition to routine postoperative care, while the comparison group will receive routine postoperative care. Pain, anxiety, nausea, and vomiting will be assessed using the study's specified assessment tools. Outcomes will be compared between groups to determine the effect of foot reflexology.

03

Conditions studied

  • Postoperative Pain
  • Anxiety
  • Nausea
  • Vomiting
  • Laparoscopic Cholecystectomy

Keywords

  • Foot Reflexology
  • Laparoscopic Cholecystectomy
  • Postoperative pain
  • Anxiety
  • Nausea
  • Vomiting
04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adult patients aged 18 years and older undergoing laparoscopic surgery.
  • Patients who are conscious, oriented, and able to communicate.
  • Patients who provide to participate in the study.

Exclusion criteria

Exclusion Criteria:

  • Patients with foot lesions, skin infections, fractures, or deep vein thrombosis (DVT) in the lower extremities.
  • Patients with severe neurological deficits or neuropathy affecting the lower limbs.
  • Patients with a history of severe cognitive impairment or psychiatric disorders.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
108 participants (actual)

Study arms

  • No intervention
    Control group

    "Participants receive routine postoperative nursing care and prescribed analgesics/antiemetics per hospital protocol, without receiving foot reflexology

  • Experimental
    Foot Reflexology group

    "Participants receive a 20-minute foot reflexology session (10 minutes per foot) in addition to standard postoperative nursing care

    Procedure: Foot reflexology

Interventions

  • ProcedureFoot reflexology

    "Participants receive a 20-minute foot reflexology session (10 minutes per foot) targeting specific reflex zones in addition to standard postoperative nursing care

06

What researchers measure

Primary outcomes

  1. Post operative pain

    Assess pain intensity by using Numeric Pain Rating Scale

    Time frame: Baseline preintervention and 30,90,120 minutes after intervention

Secondary outcomes

  1. Anxiety

    Burn anxiety inventory using to assess anxiety

    Time frame: Baseline preintervention and after 120 minutes after intervention

  2. Nausea and Vomiting

    Assess nausea and vomiting by using Nausea and vomiting grading scale

    Time frame: Baseline preintervention and 30,90,120 minutes after intervention

07

Study locations

1 site
  • Ain Shams University hospitals
    Cairo, Cairo Governorate, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Oct 2024 to primary completion in Apr 2025, 6 months.

Of 2,094 non-industry interventional studies with no phase under Pain, Postoperative, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 23. This study's 6 months is below that.

Counting every sponsor, half of 2,107 studies reached it within 11 months; a quarter within 6 and three quarters within 23.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 9, 2026
First posted
Aug 18, 2026
StartActual
Oct 15, 2024
Primary completionActual
Apr 30, 2025
CompletionActual
Apr 30, 2025
Last update
Aug 18, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 18, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07770295
Responsible party
Sponsor
First posted
Aug 18, 2026
Start date
Oct 15, 2024
Primary completion
Apr 30, 2025
Completion
Apr 30, 2025
Last update
Aug 18, 2026

Study contacts

Hanan Sayed Ali
study director · Faculty of Nursing Ain Shams University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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