An interventional study of oblique sandwich osteotomy augmentation in Atrophic Mandible, sponsored by Ain Shams University. Recruiting at 1 site in Egypt. Open to participants aged 42 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-12.
Sponsored by Ain Shams University · Not applicable, Interventional, and Treatment
Rehabilitation of the partially or totally edentulous mandible with implant supported prosthesis has become a common practice in the last few decades. Local conditions of the edentulous ridges may be unfavorable for dental implant placement, where sufficient bony support in both the horizontal and vertical dimensions is the foundation of any successful oral rehabilitation with dental implants.
Challenges include the resorpative changes of the alveolar ridge after tooth extractions and the hard tissue deficits due to chronic periodontal disease or congenitally missing teeth. Neoplasm, osteomyelitis, cysts or trauma can also compromise the situation. All these factors require the oral implantologist to create using regenerative techniques sufficient hard tissue support at the appropriate site before or during dental implant installation.
Multiple bone grafting materials and techniques have been used to reconstruct the partially dentate and edentulous posterior mandibular ridges with high rates of success, these techniques include block onlay grafting technique, guided bone regeneration using membranes or meshes and distraction osteogenesis. The selection of the optimal technique depends on various factors, including the degree of the defect, the grafted bone substitute available, the medical condition of the patient and also the skill and experience of the operator.
The aim of this study is to evaluate the alveolar bone volume by the CBCT after performing oblique sandwich osteotomy in conjunction with interpositional autogenous bone grafting in the atrophied posterior mandible.
Rehabilitation of the partially or totally edentulous mandible with implant supported prosthesis has become a common practice in the last few decades. Local conditions of the edentulous ridges may be unfavorable for dental implant placement, where sufficient bony support in both the horizontal and vertical dimensions is the foundation of any successful oral rehabilitation with dental implants.
Challenges include the resorpative changes of the alveolar ridge after tooth extractions and the hard tissue deficits due to chronic periodontal disease or congenitally missing teeth. Neoplasm, osteomyelitis, cysts or trauma can also compromise the situation. All these factors require the oral implantologist to create using regenerative techniques sufficient hard tissue support at the appropriate site before or during dental implant installation.
Multiple bone grafting materials and techniques have been used to reconstruct the partially dentate and edentulous posterior mandibular ridges with high rates of success, these techniques include block onlay grafting technique, guided bone regeneration using membranes or meshes and distraction osteogenesis. The selection of the optimal technique depends on various factors, including the degree of the defect, the grafted bone substitute available, the medical condition of the patient and also the skill and experience of the operator.
The aim of this study is to evaluate the alveolar bone volume by the CBCT after performing oblique sandwich osteotomy in conjunction with interpositional autogenous bone grafting in the atrophied posterior mandible.
In this study ten atrophied posterior mandibular regions will be augmented with autogenous interpositional particulate bone harvested from the ipsilateral retromolar area through the oblique sandwich osteotomy procedure. The mobilized segment will be stabilized by using 2.0 manipulates and screws. The graft is then covered by platelet rich fibrin membrane.
Ain Shams University is the lead sponsor of 1,953 studies on the registry; 430 are open to participants now.
Of its 35 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
atrophic posterior mandibular regions wiil be augmented with autogenous interpositional particulate bone harvested from the ipsilateral retromolar area through the oblique sandwich osteotomy procedure. The mobilized segment will be stabilized by using 2.0 manipulates and screws. The graft is then covered by platelet rich fibrin membrane.
Procedure: oblique sandwich osteotomy augmentation
atrophic posterior mandibular regions is augmented with autogenous interpositional particulate bone harvested from the ipsilateral retromolar area through the oblique sandwich osteotomy procedure. The mobilized segment is stabilized by using 2.0 manipulates and screws. The graft is then covered by platelet rich fibrin membrane.
Clinical evaluation
clinical evalauation of the occurrence of any complications after augmentation involving wound dehiscence, infection, neuro-sensory disturbance and for the stability of the augmented alveolar ridges
Time frame: 4 months
Radiographic evaluation
Linear and volumetric Measurements to calculate first the post-operative CBCT bone volume then the volume of the plate is calculated separately and subtracted from the postoperative volume. The preoperative and postoperative CBCTs and the difference in volume is calculated through subtraction of postoperative and preoperative results
Time frame: 4 months
Started Aug 2026 (actual). Primary completion is estimated for Dec 2026, 4 months after the start.
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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