ClinicalTrials.gg
CompletedNCT03259360POPUpdated Jan 30, 2025

A Facebook Intervention for Young Sexual and Gender Minority Smokers

An interventional study of POP: and TSP: in Tobacco Use, Smoking and Tobacco Dependence, sponsored by University of California, San Francisco. Completed at 1 site in United States. Open to participants aged 18 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-01-30.

Primary conditionCigarette SmokingRegistry: Tobacco UseReclassifiedWhy we changed it
Registry
Tobacco Use — the first condition term the registry derived for this study.
ClinicalTrials.gg
Cigarette Smoking
Why
  1. The study's listed conditions name Cigarette Smoking, a narrower term within Tobacco Use.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by University of California, San Francisco · Not applicable, Interventional, and Treatment

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Phase
Not applicable
Study type
Interventional
Enrollment
165
Allocation
Randomized
Ages
18 Years to 25 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 12 studies in Cigarette Smoking by University of California, San Francisco — 1 open to participants now, 1 under way, none of them phase 3. Cigarette Smoking · University of California, San Francisco.

Enrollment
6th of 12
165 · median 156
Started
2018
with 1 other
No phase
9 of 12
1 open now
Registered
7th of 12
by date

Among the 12 studies in Cigarette Smoking by University of California, San Francisco, this one is the 6th largest by enrollment, is one of 2 that started in 2018, is one of 9 with no phase, and was the 7th registered.

Cigarette Smoking

475 studies on the registry are indexed under Cigarette Smoking; 86 are open to participants now.

Browse Cigarette Smoking studies →

Open to participants now

1 of the 12 studies in Cigarette Smoking by University of California, San Francisco is open now, in 1 country. Recruiting first, the newest first:

By country, each count listing its studies:

Where they have run

Who these studies take

Of the 61 Cigarette Smoking studies recruiting now, 38 (62%) set no upper age limit and 17 (28%) stop at 75 or younger; 1 takes children under 18; 32 take healthy volunteers.

This study: 18 Years to 25 Years · all sexes · healthy volunteers too.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 12 studies in Cigarette Smoking by University of California, San Francisco, or all of them as a file.
02

Study summary

The 2-year research plan will test the Put It Out Project (POP) in a pilot randomized trial (N=120) compared to TSP and two historical control conditions. Participants will be young adults who smoke, identify as sexual or gender minorities, and use Facebook. The primary outcome will be biochemically verified 7-day abstinence from smoking at 3 and 6 months. Secondary outcomes will be a quit attempt (y/n), stage of change, and thoughts about tobacco abstinence at 3 and 6 mos.

Read the detailed description

Participants will be randomized to one of two conditions: (1) a Facebook-delivered intervention addressing tobacco use, tailored to SGM young adults; or (2) a 3-month Facebook intervention targeting tobacco use. Both interventions will include 90 days of Facebook-based messages and activities tailored to participants' readiness to quit smoking.

Assessments will occur at baseline, 3, and 6 months follow-up. Assessments will include measures on smoking, thoughts about abstinence, and SGM identity experiences. All participants who report no past 7-day smoking will be asked to give biochemical verification of smoking status with saliva cotinine test kits that will be mailed to participants.

03

Conditions studied

  • Tobacco Use
  • Smoking
  • Tobacco Dependence
  • Tobacco Use Disorder
  • Tobacco Use Cessation
  • Tobacco Smoking
  • Smoking Cessation
  • Smoking, Cigarette
  • Smoking, Tobacco

Keywords

  • Tobacco
  • Gender Identity Minority
  • Sexual Identity Minority
  • Cessation
  • Intervention
  • Young Adults
  • Social Media
  • Internet
  • Cigarette
04

In context

Cigarette Smoking Reclassified

475 studies on the registry are indexed under Cigarette Smoking; 86 are open to participants now.

This study's enrollment of 165 is above the median of 96 across 406 interventional studies indexed under Cigarette Smoking.

Browse Cigarette Smoking studies →

Lead sponsor

University of California, San Francisco is the lead sponsor of 2,170 studies on the registry; 370 are open to participants now.

Of its 268 completed or terminated interventional studies of FDA-regulated products, 203 (76%) have results posted.

Compared within Cigarette Smoking, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Tobacco Use. The counts are of registry records indexed under each term, refreshed daily. How we classify →

05

Who can participate

Ages eligible
18 Years to 25 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • read English
  • between 18 and 25 years of age
  • indicate they use Facebook "most" (≥ 4) days per week
  • have smoked ≥100 cigarettes in their lives and currently smoke at least 1 cigarette per day on 4 or more days of the week
  • identifies as SGM

Exclusion criteria

Exclusion Criteria:

  • do not read English
  • are not between 18 and 25 years of age
  • indicate they do not use Facebook "most" (≥ 4) days per week
  • have not smoked ≥100 cigarettes in their lives and currently smoke at least 1 cigarette per day on 4 or more days of the week
  • does not identify as SGM
06

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
165 participants (actual)

Study arms

  • Experimental
    The Put It Out Project (POP):

    a culturally tailored intervention developed for SGM young adults on Facebook

    Behavioral: POP:

  • Experimental
    Tobacco Status Project (TSP):

    the original TSP intervention (non-tailored) delivered to groups of only SGM participants on Facebook

    Behavioral: TSP:

Interventions

  • BehavioralPOP:

    90 days of Facebook messaging, weekly live sessions targeting tobacco use and tailored to sexual and gender minority young adults

  • BehavioralTSP:

    90 days of Facebook messaging, weekly live sessions targeting tobacco use

07

What researchers measure

Primary outcomes

  1. 7-day point prevalence abstinence at 3 months

    Reports of no smoking in the 7 days prior to the 3 month assessment. Biochemical verification of abstinence will also be recorded.

    Time frame: 3 months post baseline

  2. 7-day point prevalence abstinence at 6 months

    Reports of no smoking in the 7 days prior to the 6 month assessment. Biochemical verification of abstinence will also be recorded.

    Time frame: 6 months post baseline

Secondary outcomes

  1. Reduction in cigarettes smoked by at least 50%

    Reduction will be assessed at 3 and 6 month follow-ups.

    Time frame: 3 and 6 months post baseline

  2. Tobacco use quit attempts

    Whether a quit attempt was made during the follow-up period at 3 and 6 months post-baseline.

    Time frame: 3 and 6 months post baseline

  3. Readiness to quit tobacco

    Proportion of participants ready to quit smoking in the next month assessed at 3 and 6 months

    Time frame: 3 and 6 months post baseline

  4. Thoughts About Tobacco Abstinence

    Desire to quit, abstinence self-efficacy, perceived difficulty of quitting and abstinence goal

    Time frame: 3 and 6 months post baseline

08

Study locations

1 site
  • University of California San Francisco Department of Psychiatry
    San Francisco, California 94143, United States
09

References and documents

Publications

  • Ramo DE, Thrul J, Chavez K, Delucchi KL, Prochaska JJ. Feasibility and Quit Rates of the Tobacco Status Project: A Facebook Smoking Cessation Intervention for Young Adults. J Med Internet Res. 2015 Dec 31;17(12):e291. doi: 10.2196/jmir.5209. PubMed 26721211 ↗
  • Thrul J, Klein AB, Ramo DE. Smoking Cessation Intervention on Facebook: Which Content Generates the Best Engagement? J Med Internet Res. 2015 Nov 11;17(11):e244. doi: 10.2196/jmir.4575. PubMed 26561529 ↗
  • Ramo DE, Thrul J, Delucchi KL, Ling PM, Hall SM, Prochaska JJ. The Tobacco Status Project (TSP): Study protocol for a randomized controlled trial of a Facebook smoking cessation intervention for young adults. BMC Public Health. 2015 Sep 15;15:897. doi: 10.1186/s12889-015-2217-0. PubMed 26374203 ↗
  • Ramo DE, Rodriguez TM, Chavez K, Sommer MJ, Prochaska JJ. Facebook Recruitment of Young Adult Smokers for a Cessation Trial: Methods, Metrics, and Lessons Learned. Internet Interv. 2014 Apr;1(2):58-64. doi: 10.1016/j.invent.2014.05.001. PubMed 25045624 ↗
  • Ramo DE, Liu H, Prochaska JJ. A mixed-methods study of young adults' receptivity to using Facebook for smoking cessation: if you build it, will they come? Am J Health Promot. 2015 Mar-Apr;29(4):e126-35. doi: 10.4278/ajhp.130326-QUAL-128. Epub 2014 Feb 27. PubMed 24575728 ↗
  • Vogel EA, Ramo DE, Meacham MC, Prochaska JJ, Delucchi KL, Humfleet GL. The Put It Out Project (POP) Facebook Intervention for Young Sexual and Gender Minority Smokers: Outcomes of a Pilot, Randomized, Controlled Trial. Nicotine Tob Res. 2020 Aug 24;22(9):1614-1621. doi: 10.1093/ntr/ntz184. PubMed 31562765 ↗

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: No

10

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Apr 2018 to primary completion in Apr 2019, 11 months.

Of 184 non-industry interventional studies with no phase under Cigarette Smoking, half reached primary completion within 20 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 33. This study's 11 months is below that.

Counting every sponsor, half of 191 studies reached it within 20 months; a quarter within 9 and three quarters within 32.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 21, 2017
First posted
Aug 23, 2017
StartActual
Apr 23, 2018
Primary completionActual
Apr 20, 2019
CompletionActual
Feb 28, 2020
Last update
Jan 30, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jan 30, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
11

Registry details

Key details

Study ID
NCT03259360
Responsible party
Sponsor
First posted
Aug 23, 2017
Start date
Apr 23, 2018
Primary completion
Apr 20, 2019
Completion
Feb 28, 2020
Last update
Jan 30, 2025

Study contacts

Gary L. Humfleet, PhD
principal investigator · University of California, San Francisco

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.

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