Tobacco Use Cessation clinical trials
The registry lists 276 studies for Tobacco Use Cessation across more than 10 countries. 45 are recruiting or about to start. 149 of them are mainly about Tobacco Use Cessation (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
Get an email when these change. Save the Tobacco Use Cessation studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Mayo Clinic (11) · University of California, San Francisco (11) · M.D. Anderson Cancer Center (10) · University of Minnesota (10) · Yale University (9) · Harvard School of Public Health (HSPH) (7) · Duke University (7) · Washington University School of Medicine (6)
What is being tested here
Drugs under test in Tobacco Use Cessation studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites · University of Chicago
- Dec 2026Oral Cannabidiol for Tobacco Cessation · Johns Hopkins University
- Dec 2026Community-based Mobile-assisted Brief Intervention for Smoking Cessation · National University of Singapore
- Dec 2026Trauma-Informed Care for Smoking Cessation for Pregnancy · University of California, San Francisco
- Dec 2026Adaptation and Evaluation of a Tobacco Cessation Program: An Integrated mHealth Approach · University of Alabama at Birmingham
- Feb 2027Veteran Social Support for Enhancing Use of Smoking Cessation Treatment · VA Office of Research and Development
- Feb 2027Health Warnings and Counseling for Smoking Cessation · Hitotsubashi University
- Mar 2027Automating Tobacco Cessation in Primary Care · University of Pennsylvania
- Mar 2027FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural Smokers · University of Arkansas
- Mar 2027A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities · University of Minnesota
Who these studies take
Of the 23 Tobacco Use Cessation studies recruiting now, 16 (70%) set no upper age limit and 6 (26%) stop at 75 or younger. 1 (4%) take children under 18. 3 (13%) are for women only and 0 (0%) for men only; 9 (39%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (4%) | 1 (4%) |
| 18 | 20 (87%) | 17 (74%) |
| 30 | 20 (87%) | 17 (74%) |
| 40 | 20 (87%) | 17 (74%) |
| 50 | 21 (91%) | 18 (78%) |
| 65 | 21 (91%) | 18 (78%) |
| 75 | 19 (83%) | 16 (70%) |
| 85 | 17 (74%) | 14 (61%) |
Across all 276 studies, recruiting or not: 25% stop at 75 or younger and 20% at 65; 13% take children; 6% are for women only and 2% for men only; 56% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Tobacco Use Cessation studies take
Of 116 interventional studies with no phase under Tobacco Use Cessation, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 24 mo15–40 · 116 studies | — | 26 mo15–40 · 115 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting2
- Adaptation and Testing of a Novel Text-based Tobacco Cessation and Education Intervention in Kenyan Emergency Department PatientsOct 27, 2026NCT07734727
- Automating Tobacco Cessation in Primary CareOct 21, 2026NCT07735286
Results posted3
- Tobacco Cessation at FDNYNov 5, 2026NCT05997225
- Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking CessationOct 21, 2026NCT04969978
- Comparing Smartphone to In-person Training to Scale up a Tobacco Control Program for Teachers in IndiaOct 15, 2026NCT05500235
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 276. Browse all 276 → or search them.
- Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking CessationNot yet recruitingNCT07789496Not applicable1 country
- Adaptation and Testing of a Novel Text-based Tobacco Cessation and Education Intervention in Kenyan Emergency Department PatientsRecruitingNCT07734727Not applicable1 country
- Developing a Scalable Tobacco Cessation Program for Cancer Survivors and CaregiversRecruitingNCT06851936Not applicable1 country
- Flavored Electronic Nicotine Delivery Systems to Lower Smoking and Exposure to Tobacco Toxicants Among Cigarette Smokers Interested in Quitting, REFLECT TrialNot yet recruitingNCT07896330Not applicable1 country
- Automating Tobacco Cessation in Primary CareRecruitingNCT07735286Not applicable1 country
- Multi-Theory Model-Based AI Agent Intervention for Smoking Cessation in Early-Stage Cancer PatientsNot yet recruitingNCT07827066Not applicable
- Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation TreatmentEnrolling by invitationNCT05627674Not applicable1 country
- Trauma-Informed Care for Smoking Cessation for PregnancyRecruitingNCT07129590Not applicable1 country
- Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit SmokingNot yet recruitingNCT07789132Not applicable1 country
- Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette UseNot yet recruitingNCT07786896Phase 41 country
- Effectiveness of Oral Nicotine Pouches as a Cessation Tool Among Adult Tobacco Users in PakistanNot yet recruitingNCT07785479Not applicable1 country
- Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, KenyaNot yet recruitingNCT06790342Phase 31 country
- Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAidNot yet recruitingNCT07694492Not applicable1 country
- VergeRx for Smokers Not Ready to QuitNot yet recruitingNCT07693660Not applicable1 country
- Implementation of Tobacco Cessation Programming at Community Behavioral Health SitesRecruitingNCT06837220Not applicable1 country
- Community Gateway to Health StudyEnrolling by invitationNCT07592793Not applicable1 country
- Comprehensive Tobacco Cessation for Cancer Patients and SurvivorsRecruitingNCT05805722Not applicable1 country
- Tobacco Cessation Texting Intervention for People Living With HIV Who Smoke in VietnamEnrolling by invitationNCT05863923Not applicable2 countries
- Testing ANSOS for Efficacy in Multi-Tribal Urban CommunitiesRecruitingNCT06566703Not applicable1 country
- Adaptation and Evaluation of a Tobacco Cessation Program: An Integrated mHealth ApproachRecruitingNCT04865276Not applicable1 country
- Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary CareRecruitingNCT05415761Not applicable1 country
- Integrating CHWs Into Prenatal Care for Maternal Smoking CessationRecruitingNCT06438549Not applicable1 country
- Neural Mechanisms Connecting Deficient Sleep and Smoking RelapseRecruitingNCT06609369Phase 21 country
- Health Warnings and Counseling for Smoking CessationRecruitingNCT07098065Not applicable1 country
- Cannabis-Tobacco Co-Use Treatment StudyRecruitingNCT06883162Phase 31 country
- Combination Nicotine Replacement Therapy, Cytisine, or Varenicline for Smoking CessationRecruitingNCT06832085Phase 41 country
- A Web-Based Text Messaging for Tobacco Cessation in Rural MississippiNot yet recruitingNCT07431619Not applicable
- Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSDRecruitingNCT05723588Phase 21 country
- Veteran Social Support for Enhancing Use of Smoking Cessation TreatmentRecruitingNCT05868421Not applicable1 country
- Oral Cannabidiol for Tobacco CessationRecruitingNCT05445804Phase 11 country
- An Evaluation of the Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping InterventionEnrolling by invitationNCT06483412Not applicable1 country
- Extended Intervention for Tobacco Use (EXIT) for People Experiencing HomelessnessRecruitingNCT07148232Phase 41 country
- Effectiveness of an Online Quiz in Promoting Tobacco-Related Knowledge, Attitudes, and Behaviours Among Primary StudentsRecruitingNCT06913166Not applicable1 country
- Reach Through Equitable Implementation in UtahRecruitingNCT06881069Not applicable1 country
- Enhancing Equity in Smoke-free HousingEnrolling by invitationNCT06042361Not applicable1 country
- Persistent Poverty Counties Pregnant Women With MedicaidEnrolling by invitationNCT05415371Not applicable1 country
- Evaluation of the Effectiveness of 5A-5R Counselling Services for Tobacco CessationEnrolling by invitationNCT06501209Not applicable1 country
- Development of a Smoking Cessation Video SeriesRecruitingNCT06443294Not applicable1 country
- Comparison of Nicotine Replacement Therapy and Electronic Cigarettes for Smoking Cessation in PakistanNot yet recruitingNCT06063421Not applicable1 country
- Enhanced Multicomponent Proactive Navigator-Assisted Cessation of Tobacco Use in Low-Income PatientsRecruitingNCT05750537Not applicable1 country
- Cancer Screening Smoking Cessation AND Respiratory AssessmentNot yet recruitingNCT06157957Not applicable
- Adapting a Betel Quid Cessation Program for a High-risk Community in Malaysia and Evaluating Its EffectivenessNot yet recruitingNCT05782166Not applicable1 country
- Lung Cancer Screening Implementation Among Employees at Lyon HospitalRecruitingNCT05452200Not applicable1 country
- Feasibility, Adoption and Efficacy of A Virtual Reality Smoking Cessation Program for Patients Undergoing Lung Cancer ScreeningNot yet recruitingNCT06021652Not applicable
- A Stepped Care Approach to Treating Tobacco Use in Rural VeteransNot yet recruitingNCT04501016Phase 2/31 country
- Tobacco Cessation at FDNYCompletedNCT05997225Phase 41 country
- Tobacco Cessation Care for Cancer Patients by Automated Interactive OutreachCompletedNCT05829824Not applicable1 country
- Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking CessationCompletedNCT04969978Not applicable1 country
- Comparing Smartphone to In-person Training to Scale up a Tobacco Control Program for Teachers in IndiaCompletedNCT05500235Not applicable1 country
- Development of UP2UTeacher for High School YouthCompletedNCT05396911Not applicable1 country