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CompletedNCT00763464FEMCADUpdated Jul 7, 2011

Coronary Artery Disease (CAD) in Postmenopausal Women

An interventional study of stress-echocardiography and stress-MRI in Postmenopausal Women and Stable Angina Pectoris, sponsored by RWTH Aachen University. Completed at 1 site in Germany. Open to female participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2011-07-07.

Sponsored by RWTH Aachen University · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
100
Allocation
Not applicable
Ages
40 Years and older
Sex
Female
01

Study summary

Aim of this study is the determination of a valid procedure for ischemia diagnositc in postmenopausal women.

Read the detailed description

In order to investigate which ischemia diagnostic presents which sensitivity and specificity for postmenopausal women, 100 consecutive patients presenting to our abmulance with stable angina pectoris and indication for myocardial szintigraphy will be enrolled in this study. An addidional stress-echocardiography and stress-MRI will be performed in this patients before they will reiceve their again routine coronay angiography.

The different methods for ischemia diagnostic will be compared in order to determine the most valid method for this specific population.

02

Conditions studied

  • Postmenopausal Women
  • Stable Angina Pectoris

Keywords

  • Coronary Artery Disease
  • ischemia diagnostic
03

In context

Coronary Artery Disease

5,600 studies on the registry are indexed under Coronary Artery Disease; 958 are open to participants now.

This study's planned enrollment of 100 is below the median of 123 across 3,438 interventional studies indexed under Coronary Artery Disease.

Browse Coronary Artery Disease studies →

Lead sponsor

RWTH Aachen University is the lead sponsor of 228 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years and older
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Postmenopausal women presenting to the hospital with stable Angina pectoris complaints and an indication for myocardial szintigraphy

Exclusion criteria

Exclusion Criteria:

  • CABG
  • Pacemaker or other metal implants
  • Chronic bronchitis
  • Asthma bronchiale
  • Arterial Hypotension
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
100 participants (estimated)

Interventions

  • Procedurestress-echocardiography

    stress-echocardiography will be performed once using Adenosin (140 µg/kg/min over 6 Minutes) and a contrast agent (SonoVue)

  • Procedurestress-MRI

    stress-MRI will be performed once using Adenosin (140 µg/kg/min over 6 Minutes)and a contrast agent (Gadovist)

06

What researchers measure

Primary outcomes

  1. comparision of different ischemia diagnostic methods

    Time frame: before routine coronary angiography

07

Study locations

1 site
  • Department of Cardiology, RWTH Aachen University Hospital
    Aachen, 52057, Germany
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 7, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00763464
Lead sponsor
RWTH Aachen University
First posted
Oct 1, 2008
Start date
Oct 2006
Primary completion
Apr 2011
Completion
Jun 2011
Last update
Jul 7, 2011

Study contacts

Michael Becker, MD
principal investigator · Medical Faculty of the RWTH Aachen University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2011. You cannot join it, but the record below documents what was studied.

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