National Institutes of Health: all 11,571 studies

Page 2 of 116. Open to participants first (946), then studies with results posted, then the rest; newest registration first within each.

• Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low TrialRecruitingNCT07391774Phase 3
• A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1RecruitingNCT07390955Phase 1
• Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIVRecruitingNCT07390474Phase 1
• Azacitidine and Abatacept in Relapsed or Refractory T-Cell LymphomaRecruitingNCT07388563Phase 1
• Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2 (PD1-PASC I)Not yet recruitingNCT07388550Phase 1
• Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and AdultsNot yet recruitingNCT07388537
• Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC TrialRecruitingNCT07388524Phase 3
• Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)RecruitingNCT07357701
• A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial CancerNot yet recruitingNCT07349641Phase 2
• Dasatinib for HIV-1 Reservoir ReductionRecruitingNCT07342491Phase 1
• Testing the Effect of Teclistamab on Recurrent Plasmablastic LymphomaRecruitingNCT07332507Phase 1
• Natural History Study of Early Life Exposures in Agriculture (ELEA)Enrolling by invitationNCT07328516
• CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic LeukemiaRecruitingNCT07328503Phase 2
• Human Laboratory Study of Apremilast for Alcohol Use DisorderRecruitingNCT07325266Phase 2
• Effects of Meal Macronutrients on Postprandial LipidsNot yet recruitingNCT07313787Phase 2
• Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)RecruitingNCT07308886Phase 2
• Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren DiseaseRecruitingNCT07281456Phase 2
• Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)RecruitingNCT07281430Not applicable
• Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell CarcinomaRecruitingNCT07281417Phase 2
• Study of Oral Food Challenge Biomarkers (SAFER)RecruitingNCT07279467
• THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial ToxinsRecruitingNCT07271381Not applicable
• Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic DermatitisRecruitingNCT07262983Phase 1
• Small Trial of Alendronate Impact on the Reservoir of HIVRecruitingNCT07216794Phase 2
• Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATGRecruitingNCT07216391Phase 2
• Rechallenge With a Low Pathogenicity Avian H10N7 Influenza Virus in Healthy Human Volunteers Previously Challenged With H10N7 InfluenzaEnrolling by invitationNCT07215871Phase 1
• BPL-1357 Against H1N1 Influenza Virus ChallengeRecruitingNCT07215858Phase 2
• Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)RecruitingNCT07204977Phase 1
• Phase 1 Study of Oral MG001Not yet recruitingNCT07204171Phase 1
• Randomized Stepped Wedge Study of Emapalumab in APECED EnteritisRecruitingNCT07202598Phase 2
• Steroid Treatment for Severe Acute Respiratory Infection (STAR) TrialNot yet recruitingNCT07199192Phase 4
• Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial CancerRecruitingNCT07198074Phase 3
• Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck CancerRecruitingNCT07195734Phase 2
• Hepatic Lipid Metabolism-Alcohol Use DisorderRecruitingNCT07191561
• PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)RecruitingNCT07169630Phase 1
• Testing the SurVaxM Vaccine for Lung Cancer PreventionNot yet recruitingNCT07169617Phase 2
• First-in-Human Study of VNT-101: Safety, Tolerability, and PharmacokineticsRecruitingNCT07169318Phase 1
• Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell TransplantationRecruitingNCT07162038Phase 1
• Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell CarcinomaRecruitingNCT07156227Phase 1
• Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy)Not yet recruitingNCT07153497Phase 2
• Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)RecruitingNCT07149428
• Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal CancerRecruitingNCT07147231Phase 1/2
• Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes MellitusRecruitingNCT07142252Phase 2
• EDEN Intracardiac Electrogram Recording and Classifying SystemEnrolling by invitationNCT07137455Not applicable
• Distinguishing Tics and Functional Tics Using Clinical Neurophysiological TechniquesRecruitingNCT07137442
• Platelet Volunteers, Longitudinal and Multi-omic StudyRecruitingNCT07137429
• Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast CancerRecruitingNCT07137416Phase 1
• A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIVRecruitingNCT07124559Phase 1/2
• Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous DiseaseEnrolling by invitationNCT07113743Phase 1/2
• Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and Without ALFQ Adjuvant in Healthy AdultsRecruitingNCT07111078Phase 1
• FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)RecruitingNCT07111065Phase 2
• pH1N1 Blinded Challenge StudyRecruitingNCT07110532Phase 1
• Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell ArteritisRecruitingNCT07108387Phase 2
• Ublituximab in Autoantibody Positive Immune Mediated Necrotizing MyopathyRecruitingNCT07103746Phase 2
• Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research StudyEnrolling by invitationNCT07102849
• Causal Mechanisms of Odor-Guided Behavior in HumansNot yet recruitingNCT07099092Early Phase 1
• Amyloid PET Imaging in the Baltimore Longitudinal Study of AgingRecruitingNCT07099053
• Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC GeneRecruitingNCT07069699Phase 1/2
• Using Smartwatches to Monitor Smoking in Real-life SituationsEnrolling by invitationNCT07067151
• A Synthetic Lethality-Focused Algorithm to Identify Therapeutic Options in Advanced Metastatic Breast Cancer (SYNTHESIS-Breast)RecruitingNCT07067138Not applicable
• Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical CancerRecruitingNCT07061977Phase 3
• Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT TrialRecruitingNCT07061964Phase 2
• Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic LeukemiaRecruitingNCT07061951Phase 2
• Microbiome and Atopy in MaliRecruitingNCT07051902
• Tirzepatide in MetALDRecruitingNCT07046819Phase 2
• Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune SystemRecruitingNCT07042295Phase 2
• Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIVRecruitingNCT07040319Phase 1/2
• Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)RecruitingNCT07027839Phase 1
• The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United StatesRecruitingNCT07027826Not applicable
• Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition VariantsRecruitingNCT07019155
• Efficacy of Tezepelumab in Peanut Oral ImmunotherapyRecruitingNCT07015996Phase 2
• Healing Within: Mindfulness Smoking Cessation InterventionRecruitingNCT07013968Not applicable
• A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid LeukemiaRecruitingNCT07012044Phase 1
• Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C MutationRecruitingNCT07012031Phase 1/2
• Clinical Genetics Branch Eligibility Screening SurveyNot yet recruitingNCT07005297
• Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell TherapyRecruitingNCT07003295Phase 2
• Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young AdultsRecruitingNCT06998134
• The Vanguard Study: Testing a New Way to Screen for CancerRecruitingNCT06995898Not applicable
• Development of an Interview-Informed Timeline Follow-Back (TLFB) for Opioid Use in the Era of FentanylEnrolling by invitationNCT06995885
• Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory NeuroblastomaRecruitingNCT06995872Phase 1
• A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...Not yet recruitingNCT06991751
• 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid CancerNot yet recruitingNCT06991738Phase 1/2
• A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 InfectionNot yet recruitingNCT06987318Phase 1
• Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck CancerRecruitingNCT06980038Phase 2
• Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid LoadRecruitingNCT06974877Phase 1
• Testing the Combination of Anti-cancer Drugs, Tovorafenib Plus Rituximab, in Patients With Hairy Cell LeukemiaRecruitingNCT06965114Phase 1/2
• Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient StudyRecruitingNCT06959771Phase 1/2
• Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)Not yet recruitingNCT06954987Phase 2
• Deciphering the Genetic Architecture of Autoimmune DiseasesRecruitingNCT06948110
• Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific AntibodiesRecruitingNCT06948097Phase 1
• Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First RelapseRecruitingNCT06948084Phase 2
• Study to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell DiseaseRecruitingNCT06944067
• VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) CathetersEnrolling by invitationNCT06940752Not applicable
• Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological InvolvementRecruitingNCT06923072Phase 2
• PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)RecruitingNCT06920628Phase 1
• Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (IMPROVE TRIAL)RecruitingNCT06919003Phase 2
• Treatment of Antibody-Mediated Rejection (ABMR) With CarBelRecruitingNCT06918990Phase 1
• Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)RecruitingNCT06917911Phase 2
• Pediatric NeuroimagingRecruitingNCT06912724
• Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV InfectionRecruitingNCT06908096Phase 1
• Immunologic and Virologic Parameters During Analytical Treatment Interruption Following Combination bNAb Therapy During Suppressive ARTEnrolling by invitationNCT06908083Phase 1

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