National Institutes of Health: all 11,571 studies

Page 3 of 116. Open to participants first (947), then studies with results posted, then the rest; newest registration first within each.

• Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesRecruitingNCT06904066Phase 1
• Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical CancerRecruitingNCT06900595Phase 2
• Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaRecruitingNCT06885697Phase 1
• Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative StudyRecruitingNCT06880991
• Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy VolunteersRecruitingNCT06874205Phase 1
• Phase I Trial of High-Density Theta Burst Stimulation (hdTBS)Not yet recruitingNCT06868914Phase 1
• FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory RhabdomyosarcomaRecruitingNCT06865664Phase 1
• Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy AdultsRecruitingNCT06863142Phase 1
• Environment and Alcohol: A Pilot StudyRecruitingNCT06860607Phase 1
• Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or AstrocytomaRecruitingNCT06860594Phase 1
• Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell TransplantRecruitingNCT06856226
• Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene TherapyEnrolling by invitationNCT06851767Phase 1/2
• Hormone Replacement Therapy in Adolescents With Premature Ovarian InsufficiencyRecruitingNCT06851754Phase 3
• EVR and EPO for Liver Transplant ToleranceRecruitingNCT06832189Phase 1
• Role of Metal Ion Transporter ZIP8 in Alcohol-Related BehaviorsRecruitingNCT06819189Phase 1
• Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral TherapyRecruitingNCT06819176Phase 1
• Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE TrialRecruitingNCT06811116Phase 1/2
• VK4-116 Phase I Study With Food-EffectNot yet recruitingNCT06808932Phase 1
• Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good HealthRecruitingNCT06796686Phase 1
• PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use DisorderRecruitingNCT06795581Phase 1
• Childhood-Onset Essential Hypertension Natural History StudyRecruitingNCT06778239
• Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC TrialRecruitingNCT06770582Phase 2
• Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic SequencingRecruitingNCT06749366
• A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-UpRecruitingNCT06732414
• Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's EsophagusRecruitingNCT06732388Phase 2
• Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS PatientsRecruitingNCT06730126Phase 2
• Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort StudyRecruitingNCT06730113
• Predicting Future Errors During Skill PerformanceRecruitingNCT06707207
• Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal CancerRecruitingNCT06696768Phase 1
• Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and MetabolismNot yet recruitingNCT06690294
• The Impact of Heavy Alcohol Use on Saliva and Oral HealthRecruitingNCT06684483
• Characterization of Human Immune Signatures to Zoonotic Virus Exposure in CambodiaRecruitingNCT06680843
• SMART-r: Substance Monitoring and Active Relapse Tracking RepositoryRecruitingNCT06676059
• Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic ConditionsRecruitingNCT06676046
• Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)RecruitingNCT06672146Phase 2
• Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706RecruitingNCT06665646Phase 1
• An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Podocyte DiseasesRecruitingNCT06664814Phase 2
• A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)RecruitingNCT06661915Phase 2
• Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal CancerRecruitingNCT06654037Phase 1
• Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell LymphomaRecruitingNCT06649812Phase 2
• Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing SyndromeRecruitingNCT06635629Phase 2
• A Prospective Natural History and Outcome Measure Validation Study of Congenital Myasthenic SyndromesRecruitingNCT06630650
• OurSleepKit To Support CPAP AdherenceRecruitingNCT06621511Not applicable
• Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of StrokeRecruitingNCT06615973
• Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding AssaysRecruitingNCT06607003Phase 1
• Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid CancersRecruitingNCT06606990Phase 1
• Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric AnxietyRecruitingNCT06595953Phase 2
• Genetic Analysis of Uncommon Disease Presentations in Non-US PopulationsRecruitingNCT06595940
• Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous TreatmentRecruitingNCT06589804Phase 3
• Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute InfectionRecruitingNCT06577467
• Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)RecruitingNCT06577441Phase 2
• Developing Transcranial Neuromodulation Protocols for Learning and Decision-MakingRecruitingNCT06561828Early Phase 1
• An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous PolyposisRecruitingNCT06557733Phase 2
• Thrombosis and Inflammation in Vessels Initiative (TIVI)RecruitingNCT06552767
• Cybersickness Prevention and Mitigation in Virtual Reality for Healthy VolunteersRecruitingNCT06552754Not applicable
• Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRPRecruitingNCT06552741
• A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial CancerRecruitingNCT06524544Phase 3
• Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1RecruitingNCT06517693Phase 1
• Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant DepressionRecruitingNCT06511908Phase 2
• A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)RecruitingNCT06507748Not applicable
• Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)RecruitingNCT06504160Phase 1
• 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer DetectionRecruitingNCT06503146Phase 2
• Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue SarcomaRecruitingNCT06498648Phase 1/2
• Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT TrialRecruitingNCT06498635Phase 3
• Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.RecruitingNCT06498596
• National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic DiseasesRecruitingNCT06491615
• Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical CarcinomaRecruitingNCT06487481Phase 1
• Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy VolunteersRecruitingNCT06484088Early Phase 1
• Suvorexant for Alcohol Use Disorder (AUD): Neural MechanismsRecruitingNCT06484075Phase 1/2
• Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic SyndromesRecruitingNCT06484062Phase 1
• Modeling Host-Pathogen Interaction Using Lymphoid OrganoidsRecruitingNCT06479837
• [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck CancersRecruitingNCT06479811Phase 1
• Belatacept in Heart TransplantationRecruitingNCT06478017Phase 2
• Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic AgentsRecruitingNCT06477653Phase 2
• Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant RecipientsRecruitingNCT06476132Phase 2
• Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and EffortRecruitingNCT06472622Early Phase 1
• Pregnancy Registry in MaliRecruitingNCT06468319
• Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple MyelomaRecruitingNCT06465316Phase 1
• Natural History of Depression, Bipolar Disorder and Suicide RiskRecruitingNCT06462196
• Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior ImmunotherapyRecruitingNCT06439836Phase 1
• Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand TherapyRecruitingNCT06427798Phase 1/2
• Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated SarcomasRecruitingNCT06422806Phase 3
• A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and ToxicityRecruitingNCT06406465Phase 2
• Natural History Study of Kaposi SarcomaRecruitingNCT06375122
• Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for LeukemiasRecruitingNCT06364423Phase 1/2
• Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid TumorsRecruitingNCT06364410Phase 1
• Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent GlioblastomaRecruitingNCT06344130Phase 1
• Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE StudyRecruitingNCT06339177
• Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular LymphomaRecruitingNCT06337318Phase 3
• Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat ChangeRecruitingNCT06325722Not applicable
• Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous DiseaseRecruitingNCT06325709Phase 1/2
• H01 in Adults With Interstitial Lung Disease (The SOLIS Study)RecruitingNCT06325696Phase 2
• Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged LeukemiaRecruitingNCT06317662Phase 2
• Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)RecruitingNCT06317649Phase 2
• Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin LabelingRecruitingNCT06313398Early Phase 1
• Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)RecruitingNCT06311214Phase 2
• Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative NeoplasmsRecruitingNCT06303193Phase 1/2
• NIDCD Otolaryngology Clinical Protocol Biospecimen BankRecruitingNCT06303180
• Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung CancerRecruitingNCT06287775Phase 1/2
• A Natural History Study of RYR1-Related DisordersRecruitingNCT06287762

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